Dermatologic Findings In Adult Obese Patients

Yıl 2016, Cilt: 2 Sayı: 3, 1 - 6, 30.09.2016

Kamile Demirci Nilgün Bilen Aysun Şikar Aktürk , Evren Odyakmaz Demirsoy , Zeynep Cantürk Çiğdem Çağlayan , Dilek Bayramgüler Rebiay Kıran

https://doi.org/10.30934/kusbed.358623

Öz

Objectives: There are only a few studies about the dermatological findings of obese patients in the literature. However, we aimed to investigate the dermatological findings of obese patients and the relationship of these conditions with age, menopause, number of pregnancies, and insulin resistance in our study.

Material and Methods: This study included 119 patients with a body mass index higher than 30 kg/m2 and 122 normal weight individuals as a control group. Also, the insulin resistance was calculated of the patients. The prevalences of dermatoses were compared between the two groups.

Results: The most common dermatologic finding in both groups was striae. But, there was not statistically significant difference between two groups. Plantar hyperkeratosis was found in 47.1% and 7.4% of patients in the study and control groups, respectively and the difference was statistically significant. Also the frequencies of acrochordon, acanthosis nigricans, keratosis pilaris and intertrigo were significantly higher in the obese group. Varicose veins were more common in the control group (36.9%) compared with the obese group (31.9%). There was no statistically significant difference between the patients with and without insulin resistance in terms of frequency of plantar hyperkeratosis, intertrigo, keratosis pilaris, varicose veins, striae, acrochordon and xerosis in the obese group. However, it was striking that there was insulin resistance in 13 of the 14 patients who had acanthosis nigricans.

Conclusions: Our study showed that some dermatological findings were significantly more common in obese patients. So, prevention of obesity is important in terms of prevention of these dermatoses.

Anahtar Kelimeler

Obesity, skin manifestations, insulin resistance

Erişkin Obez Hastalarda Dermatolojik Bulgular

Öz

Amaç: Obez hastalardaki dermatolojik bulgularla ilişkili olarak literatürde çok az sayıda çalışma bulunmaktadır. Bu nedenle çalışmamızda obez hastalardaki deri bulgularını ve bunların yaş, menapoz, gebelik sayısı ve insülin direnci ile ilişkilerinin araştırması amaçlanmıştır.

Gereç ve Yöntemler: Bu çalışma vücut kitle indeksi 30 kg/m2nin üzerinde olan 119 hastayı ve kontrol grubu olarak normal kiloya sahip 122 bireyi kapsamaktadır. Dematozların görülme sıklıkları iki grup arasında karşılaştırılmıştır.

Bulgular: Her iki grupta da en sık rastlanan dermatolojik bulgu stria idi. Ancak iki grup arasında istatistiksel anlamlı bir farklılık yoktu. Plantar hiperkeratoz çalışma ve kontrol gruplarında sırasıyla % 47,1 ve % 7,4 oranlarında bulundu ve farklılık istatistiksel olarak anlamlıydı. Aynı zamanda akrokordon, akantozis nigrikans, keratozis pilaris ve intertrigo sıklığı obez grupta anlamlı olarak yüksekti. Variköz venler kontrol grubunda (% 36,9) obez grup (% 31,9) ile karşılaştırıldığında daha sık gözlendi. Çalışma grubunda insülin direnci olan ve olmayan olgular plantar hiperkeratoz, intertrigo, keratozis pilaris, variköz venler, stria, akrokordon ve kserosis görülme sıklıklarına göre karşılaştırıldığında istatistiksel olarak anlamlı bir farklılık yoktu. Ancak akantozis nigrikans olan 14 olgunun 13’ünde insülin direnci olması çarpıcı bir bulguydu.

Sonuç: Çalışmamız göstermiştir ki bazı dermatolojik bulgular obez hastalarda daha sıktır. Dolayısıyla obezitenin önlenmesi bu dermatozların da önlenmesini sağlayacaktır.

Anahtar Kelimeler

Obezite, deri bulguları, insülin direnci

Kaynakça

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