Olgu Sunumu
BibTex RIS Kaynak Göster

Zorlayıcı ve Nadir Bir Vaka: Karaciğerin Mukoepidermoid Karsinomu

Yıl 2023, , 361 - 364, 31.08.2023
https://doi.org/10.24938/kutfd.1318745

Öz

Mukoepidermoid karsinom tükürük bezinin en sık malign tümörü olup diğer organlarda nadiren görülür. Literatürde karaciğerde yerleşim gösterdiği bildirilen 20’den az vaka vardır. Biz de nadir bulunan karaciğerin primer mukoepidermoid karsinomu vakasını literatür eşliğinde sunduk. Karaciğerde kitle tespit edilen 70 yaşında kadın hastanın karaciğer segmentektomi spesimeni incelendi. Mikroskopik olarak epidermoid, müsinöz ve intermediate olmak üzere üç tip hücrenin karışık popülasyonundan oluşan tümör izlendi. Kapsamlı tarama sonrası karaciğer dışı olası odak tespit edilmeyen hastada tümör, karaciğerin primer mukoepidermoid tümörü olarak tanı aldı.

Mukoepidermoid karsinom karaciğerde nadir görülmesi, skuamöz hücreli karsinom ve adenoskuamöz hücreli karsinom gibi tümörleri taklit etmesi nedeniyle dikkatli ve kapsamlı mikroskopik muayenenin ve ayırıcı tanının önemli olduğu malignitedir.

Kaynakça

  • Dahan LS, Giorgi R, Vergez S, Le Taillandier de Gabory L, Costes-Martineau V, Herman P, et al. Mucoepidermoid carcinoma of salivary glands: A French Network of Rare Head and Neck Tumors (REFCOR) prospective study of 292 cases. Eur J Surg Oncol. 2021;47(6):1376-83.
  • Katabi N, Ghossein R, Ali S, Dogan S, Klimstra D, Ganly I. Prognostic features in mucoepidermoid carcinoma of major salivary glands with emphasis on tumour histologic grading. Histopathology. 2014;65(6):793-804.
  • Hou P, Su X, Cao W, Xu L, Zhang R, Huang Z, et al. Whole-exome sequencing reveals the etiology of the rare primary hepatic mucoepidermoid carcinoma. Diagn Pathol. 2021;16(1):29.
  • Brandwein MS, Ivanov K, Wallace DI, Hille JJ, Wang B, Fahmy A, et al. Mucoepidermoid carcinoma: A clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol. 2001;25(7):835-45.
  • Pianzola LE, Drut R. Mucoepidermoid carcinoma of the liver. Am J Clin Pathol. 1971;56(6):758-61.
  • Koo J, Ho J, Wong J, Ong GB. Mucoepidermoid carcinoma of the bile duct. Ann Surg. 1982;196(2):140-8.
  • Katsuda S, Nakanishi I, Kajikawa K, Takabatake S. Mucoepidermoid carcinoma of the liver. Acta Pathol Jpn. 1984;34(1):153-7.
  • Arakawa Y, Shimada M, Ikegami T, Kubo T, Imura S, Morine Y, et al. Mucoepidermoid carcinoma of the liver: Report of a rare case and review of the literature. Hepatol Res. 2008;8(7):736-42.

MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE

Yıl 2023, , 361 - 364, 31.08.2023
https://doi.org/10.24938/kutfd.1318745

Öz

Mucoepidermoid carcinoma is the most common malignant tumor of the salivary gland. It rarely occurs in other organs. Less than 20 cases of mucoepidermoid carcinoma of liver have been reported in the literature.

A 70-year-old woman with a liver mass is reported in this case report. After liver segmentectomy operation, the specimen was examined microscopically, a tumor consisting of epidermoid, mucinous, and intermediate cells was observed. It was interpreted as mucoepidermoid carcinoma. As no other focus was detected from comprehensive scanning of the patient, it was diagnosed as primary mucoepidermoid carcinoma of liver. Due to mimicking other tumors such as adenosquamous carcinoma and squamous cell carcinoma; cautious examination and differential diagnosis are important.

Kaynakça

  • Dahan LS, Giorgi R, Vergez S, Le Taillandier de Gabory L, Costes-Martineau V, Herman P, et al. Mucoepidermoid carcinoma of salivary glands: A French Network of Rare Head and Neck Tumors (REFCOR) prospective study of 292 cases. Eur J Surg Oncol. 2021;47(6):1376-83.
  • Katabi N, Ghossein R, Ali S, Dogan S, Klimstra D, Ganly I. Prognostic features in mucoepidermoid carcinoma of major salivary glands with emphasis on tumour histologic grading. Histopathology. 2014;65(6):793-804.
  • Hou P, Su X, Cao W, Xu L, Zhang R, Huang Z, et al. Whole-exome sequencing reveals the etiology of the rare primary hepatic mucoepidermoid carcinoma. Diagn Pathol. 2021;16(1):29.
  • Brandwein MS, Ivanov K, Wallace DI, Hille JJ, Wang B, Fahmy A, et al. Mucoepidermoid carcinoma: A clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol. 2001;25(7):835-45.
  • Pianzola LE, Drut R. Mucoepidermoid carcinoma of the liver. Am J Clin Pathol. 1971;56(6):758-61.
  • Koo J, Ho J, Wong J, Ong GB. Mucoepidermoid carcinoma of the bile duct. Ann Surg. 1982;196(2):140-8.
  • Katsuda S, Nakanishi I, Kajikawa K, Takabatake S. Mucoepidermoid carcinoma of the liver. Acta Pathol Jpn. 1984;34(1):153-7.
  • Arakawa Y, Shimada M, Ikegami T, Kubo T, Imura S, Morine Y, et al. Mucoepidermoid carcinoma of the liver: Report of a rare case and review of the literature. Hepatol Res. 2008;8(7):736-42.
Toplam 8 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Hizmetleri ve Sistemleri (Diğer)
Bölüm Olgu Sunumu
Yazarlar

Arzu Hazal Aydın 0000-0003-2591-7037

Seda Yamak 0000-0001-6609-2428

Göktürk Gürsoy 0000-0003-1449-9060

İkbal Ovalı Erdoğdu 0000-0002-7944-0310

Yusuf Bayram Özoğul 0000-0002-9953-2343

Yayımlanma Tarihi 31 Ağustos 2023
Gönderilme Tarihi 26 Haziran 2023
Yayımlandığı Sayı Yıl 2023

Kaynak Göster

APA Aydın, A. H., Yamak, S., Gürsoy, G., Ovalı Erdoğdu, İ., vd. (2023). MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE. The Journal of Kırıkkale University Faculty of Medicine, 25(2), 361-364. https://doi.org/10.24938/kutfd.1318745
AMA Aydın AH, Yamak S, Gürsoy G, Ovalı Erdoğdu İ, Özoğul YB. MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE. Kırıkkale Üni Tıp Derg. Ağustos 2023;25(2):361-364. doi:10.24938/kutfd.1318745
Chicago Aydın, Arzu Hazal, Seda Yamak, Göktürk Gürsoy, İkbal Ovalı Erdoğdu, ve Yusuf Bayram Özoğul. “MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE”. The Journal of Kırıkkale University Faculty of Medicine 25, sy. 2 (Ağustos 2023): 361-64. https://doi.org/10.24938/kutfd.1318745.
EndNote Aydın AH, Yamak S, Gürsoy G, Ovalı Erdoğdu İ, Özoğul YB (01 Ağustos 2023) MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE. The Journal of Kırıkkale University Faculty of Medicine 25 2 361–364.
IEEE A. H. Aydın, S. Yamak, G. Gürsoy, İ. Ovalı Erdoğdu, ve Y. B. Özoğul, “MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE”, Kırıkkale Üni Tıp Derg, c. 25, sy. 2, ss. 361–364, 2023, doi: 10.24938/kutfd.1318745.
ISNAD Aydın, Arzu Hazal vd. “MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE”. The Journal of Kırıkkale University Faculty of Medicine 25/2 (Ağustos 2023), 361-364. https://doi.org/10.24938/kutfd.1318745.
JAMA Aydın AH, Yamak S, Gürsoy G, Ovalı Erdoğdu İ, Özoğul YB. MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE. Kırıkkale Üni Tıp Derg. 2023;25:361–364.
MLA Aydın, Arzu Hazal vd. “MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE”. The Journal of Kırıkkale University Faculty of Medicine, c. 25, sy. 2, 2023, ss. 361-4, doi:10.24938/kutfd.1318745.
Vancouver Aydın AH, Yamak S, Gürsoy G, Ovalı Erdoğdu İ, Özoğul YB. MUCOEPIDERMOID CARCINOMA OF THE LIVER: A RARE, DIAGNOSTICALLY CHALLENGING CASE. Kırıkkale Üni Tıp Derg. 2023;25(2):361-4.

Bu Dergi, Kırıkkale Üniversitesi Tıp Fakültesi Yayınıdır.