Clinical and Neuroimaging Findings of Pseudotumor Cerebri in Chıildren

Öz

Objective: Pseudotumor cerebri is characterized by symptoms and signs of elevated intracranial pressure with normal cerebrospinal fluid composition in the absence of intracranial mass, structural lesion, hydrocephalus, or meningeal enhancement on neuroimaging. Although this syndrome most commonly affects female patients at childbearing age, it is also not rare in men and children. We aimed to review the clinical and neuroimaging findings in children in the present study.

Material and Methods: The records of the patients who were diagnosed with pseudotumor cerebri in our pediatric neurology department between June 2014- November 217 were retrospectively analyzed.

Results: A total of 14 patients diagnosed with pseudotumor cerebri (7 female, 7 male) were included in the study. The most common symptom was headache and it was recorded in all of the patients. Two of the patients had dural venous sinus thrombosis. Brain MRI was performed in 11 patients. Two of these 11 patients had normal imaging findings. Enlargement of subarachnoid space around the optic nerves was most common imaging findings (64%). All patients were treated medically. Only one patient in the series required endoscopic optic sheath fenestration.

Conclusion: It is shown that the prognosis of pseudotumor cerebri is good provided that early diagnosis is made and appropriate treatment and follow-up are accomplished.

Anahtar Kelimeler

• Pseudotumor cerebri,papilledema,magnetic resonance imaging,headache

ÇOCUKLARDA PSÖDOTÜMÖR SEREBRİNİN KLİNİK VE NÖROGÖRÜNTÜLEME BULGULARI

Öz

Amaç: Psödotümör serebri; kitle, yapısal lezyon, hidrosefali veya meningial kontrastlanma olmaksızın, normal beyin omurilik sıvısı içeriği ile birlikte, intrakranial basınç artışının belirti ve bulgularının olması ile karakterizedir. En sık doğurganlık çağındaki kadınları etkilemesine rağmen, çocuklar ve erkeklerde de nadir değildir. Bu çalışmanın amacı, çocuklarda psödotümör serebrinin klinik ve nörogörüntüleme bulgularını gözden geçirmektir.

Gereç ve Yöntem: Haziran 2014- Kasım 2017 yılları arasında, çocuk nöroloji kliniğimizde psödotümör serebri tanısı almış hastalar geriye dönük olarak analiz edilmiştir.

Bulgular: Toplam 14 hasta (7 kız, 7 erkek) çalışmaya dahil edildi. En sık görülen belirti başağrısı olup, hastaların tamamında kaydedildi. İki hastada dural venöz sinüs trombozu vardı. On bir olguya beyin MRG yapıldı. Bu 11 olgunun ikisinde görüntüleme bulguları normal idi. Optik sinirlerin çevresindeki subraaknoid mesafe genişlemesi en sık görüntüleme bulgusu idi (%64). Bütün hastalara medikal tedavi verildi. Olgulardan sadece birisinde endoskopik optik kılıf fenestrasyonu ihtiyacı doğmuştur.

Sonuç: Mevcut çalışmamızda, erken tanı konulup uygun tedavi ve takip edildiği taktirde, psödotümör serebrinin prognozunun iyi olduğu gösterilmiştir.

Anahtar Kelimeler

• psödotümör serebri,papilödem,manyetik rezonans görüntüleme,başağrısı

Kaynakça

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