Oğlaklarda Giardiazis Kontrolüne Yönelik Oral Klinoptilolit Uygulaması

Öz

Bu çalışma doğal zeolit olan klinoptilolitin oğlaklarda doğal yolla oluşan giardiazise karşı terapötik etkinliğinin belirlenmesi

amacıyla gerçekleştirildi. Aydın ilinde yer alan bir keçi işletmesinde ishal anamnezi bulunan G. duodenalis ile doğal enfekte

her iki cinsiyetten ve 19-41 günlük yaştaki 16 oğlak çalışma kapsamına alındı. Oğlaklar her grupta n=8 olacak şekilde

randomize olarak 2 ayrı gruba ayrılarak I. gruba 1 g/kg dozda 10 gün oral yolla klinoptilolit uygulanırken, II. gruptaki

olgulara hiçbir ilaç uygulaması yapılmayarak kontrol grubu olarak bırakıldı. Oğlaklarda klinoptilolitin terapötik etkinliği 0. ve

10. günlerde rektumdan direkt olarak toplanan dışkı numunelerinin mikroskobik muayenesiyle değerlendirildi. Gram

dışkıda kist atılımındaki azalma değerlendirildiğinde klinoptilolit giardiazise karşı 10. günde kist atılımında %95 etkinlik

sağladı. Buna karşın kontrol grubunda 0. gün ile (165832) 10. günlerde (162096) kist atılımının geometrik ortalamalarındaki

azalmanın yeterli olmadığı görüldü. Sonuç olarak giardiazisli oğlaklarda oral yolla 10 gün uygulanan klinoptilolitin kist

atılımını etkin şekilde azaltılmasına yardımcı olduğu söylenebilir.

Anahtar Kelimeler

• Giardiazis,Klinoptilolit,Oğlak

Application of Oral Clinoptilolite İntended For Prevention of Giardiasis in Goat Kids

Öz

The present study was established in an attempt to interpret treapeutic efficacy of clinoptilolite against naturally occurring

giardiasis in goat kids. A total of sixteen goat kids naturally infected with G. duodenalis at the age of 19 to 41 days, of both

sexes were enrolled into the study from a goat farm located in Aydin province. Goat kids were randomly assigned into two

groups (n=8), whereas group I received oral clinoptilolite at a dosage of 1 g/kg for 10 days, goat kids in group II were left

as control without receiving any drug. Therapeutic efficacy of clinoptilolite was determined by microscopical

interpretation of faecal samples collected from the rectum directly on days 0 and 10. Interpretation of the percentage

reduction in cyst excretion revealed clinoptilolite efficacy as 95% on day 10. Indeed geometric means of the number of

excreted cysts were not reduced sufficiently in control group between day 0 (165832) and 10 (162096). In conclusion, it

might be suggested that oral administration of clinoptilolite for 10 days may have helped significant reduction the excretion

of cysts in goat kids with giardiasis.

Anahtar Kelimeler

• Giardiasis,Clinoptilolite,Goat kid

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