Anthelmintic Resistance in Farm Animals

Abstract

Anthelmintic resistance means that developing genetically transmitted lack of susceptibility to an anthelmintic which is previously known to be susceptible to a parasite population. Anthelmintic resistance has an increasing importance in recent years. The anthelmintic resistance which is developed especially due to use of unconscious anthelmintics also brings with it economic problems. Investigations have shown that resistance has developed to anthelmintics in a short period of time after launch to the market and even in some countries, several sheep and goat farms have been closed due to anthelmintic resistance. For this reason, especially in livestock breeding; The development of resistance should not be overlooked while planning of treatment and control programs and choosing anthelmintics. In this review, resistance mechanisms which is developed to anthelmentic drugs, resistance detection methods and anthelmentic resistance status of livestock in Turkey were evaluated.

Keywords

• Anthelmintics,Cattle,Goat,Resistance,Sheep

Çiftlik Hayvanlarında Antelmentik Direnç

Öz

Bir parazit populasyonunun daha önce duyarlı olduğu bir antelmentiğe karşı gelişen ve genetik yolla aktarılan duyarlılık kaybı olarak değerlendirilen antelmentik direnç, son yıllarda giderek artan bir öneme sahiptir. Özellikle bilinçsiz ilaç kullanımına bağlı olarak gelişen antelmentik direnç ekonomik problemleri de beraberinde getirmektedir. Yapılan araştırmalar bazı ilaçların piyasaya sürümünü takiben kısa süreler içinde ilaca karşı bir direnç geliştiğini hatta bazı ülkelerde sadece direnç gelişmine bağlı olarak çiftliklerin kapatıldığı göstermektedir. Bu nedenle özellikle çiftlik hayvanları yetişrtiriciliğinde; antelmentik kullanılırken veya helmint enfeksiyonlarının tedavi ve kontrol programları planlanırken direnç gelişimi göz ardı edilmemeilidir. Bu derlemede antelmentik ilaçlara gelişen direnç mekanizmaları ve direnç tespit yöntemleri ile Türkiye’de çiftlik hayvanlarında belirlenen antelmentik direnç hakkında özlü bilgi verilmiştir.

Anahtar Kelimeler

• Koyun,Antelmentikler,Direnç,Keçi,Sığır

Kaynakça

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