Öz
Apitherapy is a popular therapy method of the field of alternative medicine that is used to prevent and treat diseases with honey bee products. Particularly the therapy method via honey bee venom (apitoxin) is used for treatment of rhumatic, tumoral and skin diseases. The therapeutic effect of apitoxin is considered that its composition which includes peptides, enzymes and active amines are cause to biochemical and pharmacological changes in vivo. Diabetes, described as the disease of the age, is an endocrine system disease that have various types, affecting the quality of humans' and animals' life negatively or even causing death. Various precautions are taken for prevention and a variety of drugs are used for therapy of this disease which is causing damage to the world economy abundantly. However, this endocrine system disease can not be treated literally but patients are tried to back to their healthy life via protective measures and symptomatic treatment of the disease. At this point, if the effects of apitoxin on pancreas that is responsible for the endocrine aspect of diabetes are supported by adequate scientific research and if positive results can be improved, a new era will be opened in the field of diabetes treatment.