Sarcoptes scabiei ile Doğal Enfeste olan Tavşanlarda (Oryctolagus cuniculus) Eprinomektin Tedavisinin Etkinliği
Yıl 2017,
Cilt: 10 Sayı: 1, 40 - 43, 01.03.2017
Mustafa Eser
,
Durmuş Fatih Baser
Cenker Cağrı Cıngı
Hatice Çiçek
Öz
Bu çalışma, Afyon Kocatepe Üniversitesi Veteriner Fakültesi Hayvan Hastanesine göz, burun, ağız etrafında ve ayaklarda kaşıntılı yara şikâyetleri ile getirilen on iki beyaz Yeni Zelanda tavşanı (Oryctolagus cuniculus) üzerinde yürütüldü. Tavşanların lezyonlu bölgelerinden bisturi yardımıyla alınan deri kazıntıları %10’luk KOH ile ezildikten sonra ışık mikroskobunda incelendi ve tavşanların Sarcoptes scabiei ile infeste oldukları belirlendi. Tedavide eprinomektin 0.2 mg/kg ve deri altı yolla 14 gün arayla iki kez uygulandı. Eprinomektinin etkinliği; deri kazıntısının parazitolojik muayenesinde Sarcoptes scabiei akarlarının varlığı ve/veya klinik belirtilerin devam edip etmediği durumuna göre değerlendirildi. Sonuçta eprinomektinin tavşanlarda S. scabiei'nin doğal enfestasyonlarına karşı etkili olduğu belirlenmiştir.
Kaynakça
- Aguirre DH, Gaido AB, Cafrune MM, Castelli
ME, Mangold AJ, Guglielmone AA.
Eprinomectin pour-on for control of Boophilus
microplus (Canestrini) ticks (Acari: Ixodidae) on
cattle. Vet Parasitol, 2005; 127: 157-163.
- Baker CF, Tielemans E, Pollmeier MG, McCall
JW, McCall SD, Irwin J, Chester ST,
Carithers DS, Rosentel JK. Efficacy of a
singledose of a novel topical combination
product containing eprinomectin to prevent
heart worm infection in cats. Vet Parasitol,
2014; 202:49-53.
- Baker DG. Natural Pathogens of Laboratory Mice,
Rats, and Rabbits and Their Effects on
Research. Clin Microbiol Rev, 1998; 231-266.
- Baoliang P, Wang M, Xu F, Wang Y, Dong Y,
Pan Z. Efficacy of an injectable formulation
of eprinomectin against Psoroptes cuniculi, the
ear mange mite in rabbits. Vet Parasitol, 2006;
137: 386-390.
- Bilgin Z, Öter K, Tınar R, Tüzer E. Effectiveness
of eprinomectin 0.5% pour-on against
gastrointestinal nematodes in naturally
infected cattle. Turk J Vet Anim Sci, 2010; 34
(6): 541-545.
- Bornstein S, Mörner T, Samuel WM. Sarcoptes
scabiei And Sarcoptik Mange. In, Samuel WM,
Pybus MJ, Kocan AA (Eds): Parasitic
Diseases of Wild Mammals. 2nd Ed., Iowa
State University Press, USA, 2001; 107-120.
- Cringoli G, Rinaldi L, Veneziano V, Capelli G.
Efficacy of eprinomectin pour-on against
gastrointestinal nematode infections in sheep.
Vet Parasitol, 2003; 112: 203-209.
- Geurden T, Vercruysse J. Field efficacy of
eprinomectin against a natural Muellerius
capillaris infection in dairy goats. Vet Parasitol,
2007; 147: 190-193.
- Habela M, Moreno A, Gragera-Slikker A, Gomez
JM, Montes G, Rodriguez P, Alvinerie M.
Efficacy of eprinomectin pour-on in naturally
Oestrus ovis infested merino sheep in
Extremadura, South-West Spain. Parasitol
Res, 2006; 99: 275-280.
- Kettle DS. Medical and Veterinary Entomology. 2nd
Ed., C.A.B International Press, UK, 1995;
440-458.
- Kozan E, Sevimli FK, Birdane FM, Adanır R.
Efficacy of eprinomectin against Toxocara canis
in dogs. Parasitol Res, 2008; 102: 397-400.
- Kurtdede A, Karaer Z, Acar A, Güzel M, Cingi
CC, Ural K, İça A. Use of selamectin for the
treatment of psoroptic and sarcoptic mite
infestation in rabbits. Vet Dermatol. 2007; 18:
18-22.
- Meredith AL. Dermatological conditions of rodents
and rabbits. Proceedings of the 33rd World
Small Animal Veterinary Congress, Dublin-
Ireland, 2008; 250-252.
- Rambozzi L, Rossi L, MolinarMin AR, Osella
L, Bellardi S, Marchetti R, Pollicino P.
Efficacy and safety of topical eprinomectin to
control Myocoptes musculinus infestation in mice.
Braz J Vet Parasitol, 2014; 23(1): 244-247.
- Rehbein S, Winter R, Visser M, Maciel AE,
Marley SE. Chorioptic mange in dairycattle:
treatment with eprinomectin pour-on.
Parasitol Res, 2005; 98: 21-25.
- Schoeb TR, Cartner SC, Baker RA, Gerrity LW.
Parasites of Rabbits. In, Baker DG (Ed)
Flynn's Parasites of Laboratory Animals. 2nd
Ed., Blackwell Publishing, Iowa. USA, 2007;
479-480.
- Sevimli FK, Kozan E, Sevimli A, Doğan N,
Bulbul A. The acute effects of single-dose
orally administered doramectin, eprinomectin
and selamectin on natural infections of
Syphacia muris in rats. Exp Parasitol, 2009; 122:
177-181.
- Shoop W, Michael B, Egerton J, Mrozik H,
Fisher M. Titration of Subcutaneously
Administered Eprinomectin against Mature
and Immature Nematodes in Cattle. J
Parasitol, 2001; 87(6): 1466-1469.
- Shoop WL, Egerton JR, Eary CH, Haines HW,
Michael BF, Mrozik H, Eskola P, Fisher
MH, Slayton L, Ostlind DA, Skelly BJ,
Fulton RK, Barth D, Costa D, Gregory
LM, Campbell WC, Seward RL, Turner
MJ. Eprinomectin: A Novel Avermectin for
Use as a Topical Endectocide for Cattle. Int J
Parasitol, 1996; 26(11):1237-1242.
- Soulsby EJL: Helmints, Arthropods and Protozoa
of Domesticated Animals. 8th Ed., Baillere
Tindall, London, 1982, 452-475.
- Ulutas B, Voyvoda H, Bayramlı G, Karagenc T.
Efficacy of topical administration of
eprinomectin for treatment of ear mite
infestation in six rabbits. Vet Dermatol, 2005;
16:334-337.
- Visser M, Lowenstein M, Yoon S, Rehbein S.
The treatment of bovine sarcoptic mange
(Sarcoptes scabiei var. bovis) using eprinomectin
extended-release injection. Vet Parasitol, 2013;
192: 359-364.
Efficiency of Eprinomectin for the Treatment of Naturally Infested with Sarcoptes scabiei in Rabbits (Oryctolagus cuniculus)#
Yıl 2017,
Cilt: 10 Sayı: 1, 40 - 43, 01.03.2017
Mustafa Eser
,
Durmuş Fatih Baser
Cenker Cağrı Cıngı
Hatice Çiçek
Öz
This study was carried out on twelve white New Zealand rabbits (Oryctolagus cuniculus) which brought with itchy wounds symptoms around eye, nose, mouth and feet to Afyon Kocatepe University, Veterinary Faculty, Animal Hospital. The skin scrapings that taken from the lesion areas of rabbits with a scalpel, were examined in the light microscope then crushed with 10% KOH and it was determined the rabbits infested with Sarcoptes scabiei. At treatment, Eprinomectin was administered 0.2 mg/kg subcutaneously twice with 14 days interval. The efficacy of eprinomectin was assessed either clinically or parasitologically examination by the absence of Sarcoptes scabiei mites due to skin scraping. The results of the present study determine that eprinomectin is effective against naturally infestations of S. scabiei in rabbits.
Kaynakça
- Aguirre DH, Gaido AB, Cafrune MM, Castelli
ME, Mangold AJ, Guglielmone AA.
Eprinomectin pour-on for control of Boophilus
microplus (Canestrini) ticks (Acari: Ixodidae) on
cattle. Vet Parasitol, 2005; 127: 157-163.
- Baker CF, Tielemans E, Pollmeier MG, McCall
JW, McCall SD, Irwin J, Chester ST,
Carithers DS, Rosentel JK. Efficacy of a
singledose of a novel topical combination
product containing eprinomectin to prevent
heart worm infection in cats. Vet Parasitol,
2014; 202:49-53.
- Baker DG. Natural Pathogens of Laboratory Mice,
Rats, and Rabbits and Their Effects on
Research. Clin Microbiol Rev, 1998; 231-266.
- Baoliang P, Wang M, Xu F, Wang Y, Dong Y,
Pan Z. Efficacy of an injectable formulation
of eprinomectin against Psoroptes cuniculi, the
ear mange mite in rabbits. Vet Parasitol, 2006;
137: 386-390.
- Bilgin Z, Öter K, Tınar R, Tüzer E. Effectiveness
of eprinomectin 0.5% pour-on against
gastrointestinal nematodes in naturally
infected cattle. Turk J Vet Anim Sci, 2010; 34
(6): 541-545.
- Bornstein S, Mörner T, Samuel WM. Sarcoptes
scabiei And Sarcoptik Mange. In, Samuel WM,
Pybus MJ, Kocan AA (Eds): Parasitic
Diseases of Wild Mammals. 2nd Ed., Iowa
State University Press, USA, 2001; 107-120.
- Cringoli G, Rinaldi L, Veneziano V, Capelli G.
Efficacy of eprinomectin pour-on against
gastrointestinal nematode infections in sheep.
Vet Parasitol, 2003; 112: 203-209.
- Geurden T, Vercruysse J. Field efficacy of
eprinomectin against a natural Muellerius
capillaris infection in dairy goats. Vet Parasitol,
2007; 147: 190-193.
- Habela M, Moreno A, Gragera-Slikker A, Gomez
JM, Montes G, Rodriguez P, Alvinerie M.
Efficacy of eprinomectin pour-on in naturally
Oestrus ovis infested merino sheep in
Extremadura, South-West Spain. Parasitol
Res, 2006; 99: 275-280.
- Kettle DS. Medical and Veterinary Entomology. 2nd
Ed., C.A.B International Press, UK, 1995;
440-458.
- Kozan E, Sevimli FK, Birdane FM, Adanır R.
Efficacy of eprinomectin against Toxocara canis
in dogs. Parasitol Res, 2008; 102: 397-400.
- Kurtdede A, Karaer Z, Acar A, Güzel M, Cingi
CC, Ural K, İça A. Use of selamectin for the
treatment of psoroptic and sarcoptic mite
infestation in rabbits. Vet Dermatol. 2007; 18:
18-22.
- Meredith AL. Dermatological conditions of rodents
and rabbits. Proceedings of the 33rd World
Small Animal Veterinary Congress, Dublin-
Ireland, 2008; 250-252.
- Rambozzi L, Rossi L, MolinarMin AR, Osella
L, Bellardi S, Marchetti R, Pollicino P.
Efficacy and safety of topical eprinomectin to
control Myocoptes musculinus infestation in mice.
Braz J Vet Parasitol, 2014; 23(1): 244-247.
- Rehbein S, Winter R, Visser M, Maciel AE,
Marley SE. Chorioptic mange in dairycattle:
treatment with eprinomectin pour-on.
Parasitol Res, 2005; 98: 21-25.
- Schoeb TR, Cartner SC, Baker RA, Gerrity LW.
Parasites of Rabbits. In, Baker DG (Ed)
Flynn's Parasites of Laboratory Animals. 2nd
Ed., Blackwell Publishing, Iowa. USA, 2007;
479-480.
- Sevimli FK, Kozan E, Sevimli A, Doğan N,
Bulbul A. The acute effects of single-dose
orally administered doramectin, eprinomectin
and selamectin on natural infections of
Syphacia muris in rats. Exp Parasitol, 2009; 122:
177-181.
- Shoop W, Michael B, Egerton J, Mrozik H,
Fisher M. Titration of Subcutaneously
Administered Eprinomectin against Mature
and Immature Nematodes in Cattle. J
Parasitol, 2001; 87(6): 1466-1469.
- Shoop WL, Egerton JR, Eary CH, Haines HW,
Michael BF, Mrozik H, Eskola P, Fisher
MH, Slayton L, Ostlind DA, Skelly BJ,
Fulton RK, Barth D, Costa D, Gregory
LM, Campbell WC, Seward RL, Turner
MJ. Eprinomectin: A Novel Avermectin for
Use as a Topical Endectocide for Cattle. Int J
Parasitol, 1996; 26(11):1237-1242.
- Soulsby EJL: Helmints, Arthropods and Protozoa
of Domesticated Animals. 8th Ed., Baillere
Tindall, London, 1982, 452-475.
- Ulutas B, Voyvoda H, Bayramlı G, Karagenc T.
Efficacy of topical administration of
eprinomectin for treatment of ear mite
infestation in six rabbits. Vet Dermatol, 2005;
16:334-337.
- Visser M, Lowenstein M, Yoon S, Rehbein S.
The treatment of bovine sarcoptic mange
(Sarcoptes scabiei var. bovis) using eprinomectin
extended-release injection. Vet Parasitol, 2013;
192: 359-364.