KUZU VE OĞLAKLARDA KRİPTOSPORİDİOZİSTE PATOLOJİK VE İMMUNOHİSTOKİMYASAL BULGULAR

Öz

Özet: Kriptosporidiozis Cryptosporidium spp. tarafından oluşturulan zoonotik bir protozoon hastalığıdır. Neonatal dönemdeki ruminantlarda ishal ve yüksek morbidite ile seyreder. Bu çalışmanın materyalini ishal, iştahsızlık, depresyon, gelişim geriliği ve ölüm şikayetiyle getirilen ve yaşları 1-14 gün arasında değişim gösteren 10 kuzu ile 17 oğlak, toplam 27 hayvan oluşturdu. Bu araştırmada kriptosporidiozis saptanan kuzu ve oğlaklardaki makro ve mikro patolojik lezyonlar ile immunohistokimyasal bulgular değerlendirildi.

Anahtar Kelimeler

• Kuzu, Kriptosporidiozis, oğlak, patoloji

Kaynakça

1. Kaynaklar
2. Dumanlı N, Karaer Z. Veteriner Protozooloji, p. 155, Ankara: Medisan; 2010.
3. Tzanidakis N, Sotiraki S, Claerebout E, Ehsan A, Voutzourakis N, Kostopoulou D, Stijn C, Vercruysse J, Geurden T. Occurrence and molecular characterization of Giardia duodenalis and Cryptosporidium spp. in sheep and goats reared under dairy husbandry systems in Greece. Parasite. 2014;21:45.
4. Wilhelm CL, Yarovinsky F. Apicomplexan infections in the gut. Parasite Immunol. 2014; 36:409–20.
5. Bouzid M, Hunter PR, Chalmers RM, Tyler KM. Cryptosporidium pathogenicity and virulence. Clin Microb Rev. 2013; 26(1):115-34.
6. Wang R, Li G, Cui B, Huang J, Cui Z, Zhang S, Dong H, Yue D, Zhang L, Ning C, Wang M. Prevalence, molecular characterization and zoonotic potential of Cryptosporidium spp. in goats in Henan and Chongqing, China. Exp Parasitol. 2014; 142:11–6.
7. Romero-Salas D, Alvarado-Esquivel C, Cruz-Romero A, Aguilar-Domínguez M, Ibarra-Priego N, Merino-Charrez JO, Pérez de León AA, Hernández-Tinoco J. Prevalence of Cryptosporidium in small ruminants from Veracruz, Mexico. BMC Vet Res. 2016; 12 (14): 1-6.
8. Van Kruiningen HJ. Gastrointestinal system. In: Carlton WW, McGavin DV, editor. Thomson’s Special Veterinary Pathology. p.44-45. Missouri:Mosby Publishing;1995.

9. Jones TC, Hunt RD, King NW. Diseases due to protozoa. In: Jones TC, Hunt RD, King NW, editors. Veterinary Pathology, p.575-581. Pennsylvania:Williams & Wilkins Company;1997.
10. Fayer R. Cryptosporidium: a water-borne zoonotic parasite. Vet Parasitol 2004; 126(1-2): 37-56.
11. Hunter PR, Nichols G. Epidemiology and clinical features of Cryptosporidium infections in immunocomprimised patients. Clin Microbiol Rev 2002; 15(1): 145-54
12. Rossle NF, Latif B. Cryptosporidiosis as threatening health problem : a review. Asian Pac J Trop Biomed. 2013; 3:916–24.
13. Milli ÜH, Hazıroğlu R..Veteriner Patoloji, p.137. Ankara:Medipres;2000.
14. Thompson RC, Olson ME, Zhu G, Enomoto S, Abrahamsen MS, Hijjawi NS. Cryptosporidium and cryptosporidiosis. Adv Parasitol. 2005;59:77–158
15. Fahey T. Cryptosporidiosis. Primary Care Update for OB/GYNS 2003; 10(2): 75-80
16. Morgan U, Weber R, Xiao L, Sulaiman I, Thompson RC, Ndiritu W, Lal A, Moore A, Deplazes P. Molecular characterization of Cryptosporidium isolates obtained from human immunodeficiency virus-infected individuals living in Switzerland, Kenya, and the United States. J Clin Microbiol. 2000; 38:1180–3.
17. Current WL, Garcia LS. Cryptosporidiosis. Clin Microbiol Rev. 1991; 4:325–58.
18. Santín M. Clinical and subclinical infections with Cryptosporidium in animals. N Z Vet J. 2013; 61: 1–10.
19. Angus KW, Appleyard WT, Menzies JD, Campbell I, Sherwood D. An outbreak of diarrhoea associated with cryptosporidiosis in naturally reared lambs. Vet. Rec. 1982; 110:129-130.
20. Graaf DC, de Vanopdenbosch E, Ortega-Mora LM, Abbasi H, Peeters JE. A review of the importance of cyrptosporidiosis in farm animals. Int J Parasit. 1999; 29:1269-87.
21. Li P, Caib J, Caia M, Wua W, Li C, Lei M, Xua H, Fenga L, Maa J, Fenga Y, Xiaoc L. Distribution of Cryptosporidium species in Tibetan sheep and yaks in Qinghai, China. Vet Parasitol. 2016; 215:58–62.
22. Ye J, Xiao L, Wang Y, Wang L, Amer S, Roellig DM, Guo Y, Feng Y. Periparturient transmission of Cryptosporidium xiaoi from ewes to lambs. Vet Parasitol. 2013;197: 627–633.
23. Naylor JM. Diarrhea in neonatal ruminants. In: Smith BP, editor. Large Animal Internal Disease. p. 348-353. Missouri:Mosby Publishing; 1990.
24. Xiao L, Herd RP. Infection patterns of Cryptosporidium and Giardia in calves. Vet Parasitol. 1994;55: 257-62.
25. O’Handley RM, Cockwill C, McAllister TA, Jelinski M, Morck DW, Olson ME. Duration of naturally acquired giardiosis and cryptosporidiosis in dairy calves and their association with diarrhoe. JAVMA. 1999; 214: 391-6.
26. Collinet-Adler S, Babji S, Francis M, Kattula D, Premkumar PS, Sarkar R, Mohan VR, Ward H, Kang G, Balraj V, Naumova EN. Environmental factors associated with high fly densities and diarrhea in Vellore, India. Appl Environ Microbiol. 2015; 81(17):6053–8.
27. Maurya PS, Rakesh RL, Pradeep B, Kumar S, Kundu K, Garg R, Ram H, Kumar A, Banerjee PS. Prevalence and risk factors associated with Cryptosporidium spp. infection in young domestic livestock in India. Trop Anim Health Prod. 2013; 45:941–6.