Investigation of immunoglobulin G, lactoferrin and zinc levels in blood sera of calves fed fresh and frozen colostrum

Yıl 2022, Cilt: 7 Sayı: 2, 62 - 66, 31.08.2022

Süleyman Şensoy Şima Şahinduran

https://doi.org/10.24880/maeuvfd.992161

Öz

Colostrum has high nutritional values, is more easily digestible than milk, and has a comparatively higher concentration of dry matter, fat and non-fat dry matter, protein and most importantly, immunoglobulin (Ig). The most important task of immunoglobulins is to neutralize pathogens and toxins through neuttalization. Lactoferrin is a protein product of the transferrin gene family with iron binding ability. Lactoferrin serves as a major component of the secondary granules of polymorphonuclear neutrophils and is produced by epithelial cells, including those in the mammary gland. Zinc acts as a cofactor and activator of more than 300 enzymes in different metabolic pathways and is known as a biologically important trace mineral. The aim of this study is to examine whether the immunoglobulin G, lactoferrin and zinc concentrations in colostrum, which is vital for newborn calves, show a decrease tendency by freezing. Fresh colostrum was given to one group (n=12) and frozen (-20 °C) colostrum (n=12) was given to one group and blood samples were collected after 32 hours. According to the results obtained, there was no statistical difference between the groups in the initial measurements of IgG, lactoferrin and zinc values in group 1 (fresh colostrum) and group 2 (frozen colostrum). The differences between the first and second measurements among themselves in both groups were found to be statistically significant. In the second measurements between the two groups, no statistical difference was found between the values of immunoglobulin G (p= 0.996), lactoferrin (p = 0.513), zinc (p = 0.605).

Anahtar Kelimeler

Colostrum,, freezing, immunoglobulin, lactoferrin, zinc

Destekleyen Kurum

Burdur Mehmet Akif Ersoy Üniversitesi, Bilimsel Araştırma Projeleri Birimi

Proje Numarası

0627-YL-20

Teşekkür

This study was supported by Burdur Mehmet Akif Ersoy University Scientific Research Projects Commission (Project No: 0627-YL-20).

Kaynakça

• 1. Arcagök B, Özdemir N, Yıldız İ, Celkan T. Çocukluk çağında demir eksikliğinin kan çinko düzeyi ile ilişkisi. Türkiye Çocuk Hast Derg. 2013: 56, 63-70.
• 2. Aydoğdu U. Sütçü İneklerde Kolostrum Kompozisyonu ve Kalitesinin Buzağı Pasif İmmunite Etkileri. Doktora Tezi Selçuk Üniversitesi Sağlık Bilimleri Enstitüsü. Konya. 2014.
• 3. Chasapis CT, Loutsidou AC, Spiliopoulou CA, Stefanidou ME. Zinc and human health an update. Arch. Toxicol. 2012; 86, 521–534.
• 4. Costa JFDR, Novo SMF, Baccili CC, Sobreira NM , Hurley DJ , Gomes V. Innate immune response in neonate Holstein heifer calves fed fresh or frozen colostrum. J. Res. Vet. Med., 2017; 115, 54-60.
• 5. Diker KS. Bağışıklığın Yapısal Unsurları Carlı KT (ed). Temel Veteriner Mikrobiyoloji ve İmmunoloji. Anadolu Üniversitesi WebOfset Tesisleri, Eskişehir. 2011. p. 121-137.
• 6. Elmasoğlu İO. Akut ishalli buzağılarda serum demir, bakır ve çinko konsantrasyonlarının değerlendirilmesi. Yüksek Lisans Tezi T.C. Adnan Menderes Üniversitesi Sağlık Bilimleri Enstitüsü, Aydın. 2008.
• 7. Erdem H, Atasever S. Yeni Doğan Buzağılarda Kolostrumun Önemi. OMÜ Zir. Fak. Der., 2005: 20, 79-84.
• 8. Holloway NM, Tyler JW, Lakritz J, Carlson SL, Holle J Serum immunoglobulin G concentrations in calves fed fresh and frozen colostrum. J. Am. Vet. Med., 2001: 219, 357-359.
• 9. Holloway NM, Tyler JW, Lakritz J, Carlson, SL, Tessman RK, Holle J. Serum Immunoglobulin G Concentrations in Calves Fed Fresh Colostrum or a Colostrum Supplement. J. Vet Intern Med., 2002: 16, 187–191.
• 10. Koyuncu M, Karaca M. Buzağılarda Yaşam Güçünün Anahtarı ‘Kolostrum’. J. Anim. Prod., 2018: 59, 67-78.
• 11. Lakritz J, Tyler JW, Hostetler DE, Bataklık AE , DM Dokumacı DM , JM Holle et al. Effects of pasteurization of colostrum on subsequent serum lactoferrin concentration and neutrophil superoxide production in calves. Am. J. Vet. Res., 2000: 61, 1021-1025.
• 12. Legrand D, Elass E, Marangoz M, Mazurier J. Lactoferrin: a modulator of immune and inflammatory responses. Cellular and Molecular Life Sciences 2005: 62, 2549–2559.
• 13. Leyton WG, David EJC, Don EO, Indyk HE. Analysis of bovine immunoglobulin G in milk, colostrum and dietary supplements: a review. Anal. Bioanal. Chem., 2007: 389, 93–109.
• 14. Lönnerdal B, Iyer S. Lactoferrin: molecular structure and biological function. Ann. Rev. Nutr., 1995; 15, 93-110.
• 15. Önder F, Yıldız S. Çinko ve bakır yetersizliğinin bağışıklık sistemine etkileri. Kafkas Üniv. Vet. Med. J., 2002: 8, 183-187.
• 16. Pavlata L, Pechova A, Dvorak R. Microelements in Colostrum and Blood of Cows and their Calves during Colostral Nutr. Acta Vet. Brno, 2004: 73, 421-429.
• 17. Tsuji S, Hirata Y, Mukai F Ohtagaki S. Comparison of lactoferrin content in colostrum between different cattle breeds. J. Dairy. Sci., 1990: 73, 125-128.
• 18. Yıldırım Z, Tokatlı M, Öncül N, Yıldırım M. Laktoferrinin Biyolojik Aktivitesi. Akademik Gıda, 2011: 9, 52-63