Tip 2 diyabetli hastalar arasında hepatosteatoz, safra taşı ve tiroid hastalıkları insidansı

Yıl 2019, Cilt: 11 Sayı: 3, 71 - 76, 30.12.2019

Yasemin Gül Aydemir , Mehmet Yamak

Öz

ÖZET
GİRİŞ VE AMAÇ
Tip 2 diyabetli hastalarda hemoglobin A1C düzeyi, lipid profili, serum ALT, GGT ve hemoglobin düzeyinin ultrasound bulguları eşliğinde inceleyerek hepatosteatoz, safra taşı ve tiroid hastalıkları sıklığını incelemeyi amaçladık.

GEREÇ VE YÖNTEM
Tekirdağ Malkara devlet hastanesi iç hastalıkları polikliniğine 01.08.2016-01.09.2017 tarihleri arasında gelen 136 tip 2 diyabetik hasta çalışmaya dahil edildi. Tip 2 diyabetli hastalarda hemoglobin A1C düzeyi, lipid profili, serum ALT, GGT ve hemoglobin düzeyinin ultrasound bulguları eşliğinde inceleyerek hepatosteatoz, safra taşı ve tiroid hastalıkları taşı sıklığı değerlendirildi.
BULGULAR
Safra taşı olan olgularda hepatosteatoz görülme oranı (%87.9), safra taşı olmayan olgulardan (%69.4) daha yüksek olmakla birlikte bu farklılık anlamlılığa yakın ancak istatistiksel olarak anlamlı bulunmamıştır (p>0.05).

SONUÇ
Ultrasound ve laboratuar bulguları eşliğinde metabolik sendromlu hastalarda safra taşı, hepatosteatoz, lipid profilinde hdl düşüklüğü, trigliserit yüksekliği ve tiroid hastalıklarının (tiroidit ve tiroid nodülü) birlikte sık tespiti ile birbirleri arasında bir ilişki olduğunu ortaya koymuştur.

ABSTRACT
AİM: The aim of this study was to investigate the frequency of hepatosteatosis, gallstones and thyroid disorders in patients with type 2 diabetes by examining lipid profile, hemoglobin a1c, serum ALT, GGT and hemoglobin levels together with findings in ultrasound.

METHODS: 136 type 2 diabetic patients who were admitted to Ministry of Health, Malkara State Hospital internal medicine outpatient clinic between 01.08.2016-01.09.2017 were included. The incidence of nonalcoholic fatty liver disease (NAFLD), renal cyst, and gallstones were evaluated in all patients with type 2 diabetes by examining lipid profile, hemoglobin A1C, serum ALT, GGT and hemoglobin levels together with ultrasound findings.


RESULTS: Although the rate of hepatosteatosis was higher in patients with gallstones (87.9%) than the cases without gallstones (69.4%), this difference was close to significance but not statistically significant (p> 0.05).

CONCLUSION:
In the presence of ultrasound and laboratory findings, it was found that there was a correlation between gallstones, hepatosteatosis, decrease in hdl,increase in triglyceride and thyroid diseases (thyroiditis and thyroid nodule) in patients with metabolic syndrome

Anahtar Kelimeler

Tip 2 diyabet, hepatosteatoz, safra kesesi taşı

Kaynakça

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