Öz
Granuloma annulare is a necrobiotic disorder of undisclosed etiology. The clinical variants include localized, generalized, perforating and subcutaneous types. Generalized granuloma annulare is characterized by derma- colored or erythematous papules in an annular configuration, with pruritus as a chief complaint.Here, we report a rare case of generalized granuloma annulare who presented with unusual symptoms and had a delay in getting the correct diagnosis and treatment
Anahtar Kelimeler
Generalized granuloma gnnulare histopathology differential diagnosis
Kaynakça
- Burns DA. Necrobiotic disorders. In: Burns T, Breathnach S, Cox NH, Griffiths C, editors. Rook’s text book of dermatology. 8th ed. Oxford: Wiley-Blackwell; 2010. p. 60.1.p. 60.12.
- Piette EW, Rosenbach M. Granuloma annulare: clinical and histologic variants, epidemiology, and genetics. J AmAcadDermatol. 2016;75:457–465.
- Mempel M, Musette P, Flageul B, Schnopp C, Remling R, Gachelin G, et al. T-cell receptor repertoire and cytokine pattern in granuloma annulare: defining a particular type of cutaneous granulomatous inflammation. J InvestDermatol. 2002;118:957–966.
- Ragunatha S, Anitha B, Inamadar AC, Palit A, Devarmani SS. Cutaneous disorders in 500 diabetic patients attending diabetic clinic. Indian J Dermatol. 2011;56:160–164.
- Wu W, Robinson-Bostom L, Kokkotou E, Jung HY, Kroumpouzos G. Dyslipidemia in granuloma annulare: a case-control study. ArchDermatol. 2012;148:1131– 1136.
- Sahin MT, TürelErmertcan A, Öztürkcan S, Türkdoğan P. Generalized granuloma annulare in a patient with type II diabetes mellitus: successful treatment with isotretinoin. J EurAcad Dermatol Venereol 2006;20(1): 111-114
- Friedman-Birnbaum R, Haim S, Gideone O, Barzilai A. Histocompatibility antigens in granuloma annulare. Comparative study of the generalized and localized types. Br J Dermatol. 1978;98:425-428.
- Tak CP. Granuloma annulare: review of cases in the Social Hygiene Service and a case-control study of its association with diabetes mellitus [dissertation]. Hong Kong: Hong Kong College of Physicians; 2003
- Yun JH, Lee JY, Kim MK, et al. Clinical and pathological features of generalized granuloma annulare with their correlation: a retrospective multicenter study in Korea. Ann Dermatol. 2009;21:113-119.
- Dabski K, Winkelmann RK. Generalized granuloma annulare: histopathology and immunopathology. Systematic review of 100 cases and comparison with localized granuloma annulare. J Am Acad Dermatol. 1989;20:28-39 .
- Calonje JE, Brenn T, Lazar A, Mckee P. McKee’s Pathology of the Skin. In: McKee’s Pathology of the Skin. 4th ed. Saunders; 2011:288-295.
Öz
Granüloma Annulare etiyolojisı net olarak bilinmeyen nekrobiyotik bir hastalıktır. Lokalize, jeneralize, perforan ve subkutanöz formları bulunmaktadır. Jeneralize granuloma anulare, anuler şekilli, cilt renginde yada eritematöz görünümlü papullerle karakterize olup ana yakınma kaşıntıdır. Atipik semptomlarından dolay tanı ve tedavide gecikme yaşamış olan nadir jeneralize granüloma anulare olgusunu sunduk
Anahtar Kelimeler
Kaynakça
- Burns DA. Necrobiotic disorders. In: Burns T, Breathnach S, Cox NH, Griffiths C, editors. Rook’s text book of dermatology. 8th ed. Oxford: Wiley-Blackwell; 2010. p. 60.1.p. 60.12.
- Piette EW, Rosenbach M. Granuloma annulare: clinical and histologic variants, epidemiology, and genetics. J AmAcadDermatol. 2016;75:457–465.
- Mempel M, Musette P, Flageul B, Schnopp C, Remling R, Gachelin G, et al. T-cell receptor repertoire and cytokine pattern in granuloma annulare: defining a particular type of cutaneous granulomatous inflammation. J InvestDermatol. 2002;118:957–966.
- Ragunatha S, Anitha B, Inamadar AC, Palit A, Devarmani SS. Cutaneous disorders in 500 diabetic patients attending diabetic clinic. Indian J Dermatol. 2011;56:160–164.
- Wu W, Robinson-Bostom L, Kokkotou E, Jung HY, Kroumpouzos G. Dyslipidemia in granuloma annulare: a case-control study. ArchDermatol. 2012;148:1131– 1136.
- Sahin MT, TürelErmertcan A, Öztürkcan S, Türkdoğan P. Generalized granuloma annulare in a patient with type II diabetes mellitus: successful treatment with isotretinoin. J EurAcad Dermatol Venereol 2006;20(1): 111-114
- Friedman-Birnbaum R, Haim S, Gideone O, Barzilai A. Histocompatibility antigens in granuloma annulare. Comparative study of the generalized and localized types. Br J Dermatol. 1978;98:425-428.
- Tak CP. Granuloma annulare: review of cases in the Social Hygiene Service and a case-control study of its association with diabetes mellitus [dissertation]. Hong Kong: Hong Kong College of Physicians; 2003
- Yun JH, Lee JY, Kim MK, et al. Clinical and pathological features of generalized granuloma annulare with their correlation: a retrospective multicenter study in Korea. Ann Dermatol. 2009;21:113-119.
- Dabski K, Winkelmann RK. Generalized granuloma annulare: histopathology and immunopathology. Systematic review of 100 cases and comparison with localized granuloma annulare. J Am Acad Dermatol. 1989;20:28-39 .
- Calonje JE, Brenn T, Lazar A, Mckee P. McKee’s Pathology of the Skin. In: McKee’s Pathology of the Skin. 4th ed. Saunders; 2011:288-295.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Case Report |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Nisan 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 11 Sayı: 1 |