Investigation of Mean Platelet Volume/Platelet, Neutrophil/Leucocyte Ratio And Troponin Values in Geriatric Patients Admitted to Hospital with Ischaemic Stroke

Yıl 2024, , 130 - 136, 30.08.2024

Gül Şahika Gökdemir

https://doi.org/10.30565/medalanya.1493400

Öz

Aim: The aim of this study was to investigate the mean MPV/PLT ratio, NLR and troponin I levels in geriatric patients admitted to hospital with acute ischaemic stroke (AIS) and to evaluate the prognostic value of these parameters. In this way, a better clinical decision can be provided in the evaluation and treatment processes of AIS patients.

Methods: Using a retrospective design, the data of geriatric patients admitted to hospital with a diagnosis of AIS were analyzed. Demographic characteristics, clinical findings, laboratory results and radiological findings were obtained from electronic medical records. Platelet volume, platelet count, neutrophil count, leukocyte count and troponin I levels were recorded as primary data and other demographic, clinical and laboratory parameters were recorded as secondary data.

Results: MPV/PLT ratio was significantly higher in AIS patients (0.04±0.02) compared to non-ischemic stroke patients (0.03±0.02) (p<0.001). Similarly, NLR (5.29±5.09) was significantly higher in AIS patients compared to the other group (1.93±0.87) (p<0.001). In addition, Troponin I level was significantly higher in AIS patients (10.48±7.88 ng/mL) than the other group (2.18±1.11 ng/mL) (p<0.001).

Conclusion: This study demonstrates the predictive value of mean MPV/PLT ratio, NLR, and troponin I levels in geriatric patients admitted to hospital with AIS. Using these parameters in clinical evaluations may be helpful in the follow-up of AIS patients and in determining treatment strategies.

Anahtar Kelimeler

Ischaemic stroke, Mean Platelet Volume/Platelet ratio, Neutrophil/Leukocyte ratio, Troponin I

Etik Beyan

This study was approved by the scientific research ethics committee of Mardin Artuklu University (Date: 10.07.2023, decision no 2023/7-12).

Destekleyen Kurum

None

Teşekkür

I would like to thank the data processing and documentation staff of our hospital for their devoted contributions

Hastaneye İskemik inme ile Başvuran Geriatrik Hastalarda Ortalama Trombosit Hacmi/Trombosit, Nötrofil/Lökosit Oranı Ve Troponin Değerlerinin Araştırılması

Öz

Amaç: Bu çalışmanın amacı, iskemik inme ile hastaneye başvuran geriatrik hastalarda ortalama MPV/PLT oranı, NLR ve troponin I düzeylerini araştırmak ve bu parametrelerin prognostik değerlerini değerlendirmektir. Bu şekilde, iskemik inme hastalarının değerlendirme ve tedavi süreçlerinde daha iyi bir klinik karar verme sağlanabilir.

Yöntem: Geriye dönük bir tasarım kullanılarak, iskemik inme tanısıyla hastaneye başvuran geriatrik hastaların verileri retrospektif olarak incelendi. Hastaların demografik özellikleri, klinik bulguları, laboratuvar sonuçları ve radyolojik bulguları elektronik tıbbi kayıtlardan elde edildi. Trombosit hacmi, platelet sayısı, nötrofil sayısı, lökosit sayısı ve troponin I düzeyleri primer veriler, diğer demografik, klinik ve laboratuvar parametreleri de ikincil veriler olarak kaydedildi.

Bulgular: MPV/PLT oranı, iskemik inme hastalarında (0,04±0,02) iskemik inme olmayan hastalara (0,03±0,02) göre anlamlı oranda daha yüksek olarak gözlemlendi (p<0,001). Benzer olarak iskemik inme hastalarında NLR (5,29±5,09), diğer gruba oranla (1,93±0,87) anlamlı oranda daha yüksek idi (p<0,001). Buna ek olarak Troponin I düzeyi, iskemik inme hastalarında (10,48±7,88 ng/mL) diğer gruptan (2,18±1,11 ng/mL) bariz olarak yüksek idi (p<0,001).

Sonuç: Bu çalışma, iskemik inme ile hastaneye başvuran geriatrik hastalarda ortalama MPV/PLT oranı, NLR ve troponin I düzeylerinin prognostik değerlerini ortaya koymaktadır. Bu parametrelerin klinik değerlendirmelerde kullanılması, iskemik inme hastalarının takibinde ve tedavi stratejilerinin belirlenmesinde yardımcı olabilir.

Anahtar Kelimeler

İskemik inme, Ortalama Trombosit Hacmi /Platelet oranı, Nötrofil/Lökosit oranı, Troponin I

Kaynakça

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