Management of the heparin induced thrombocytopenia in the course of acute myocardial infarction
Yıl 2020,
, 193 - 196, 12.07.2020
Ali Çoner
,
Sinan Akıncı
,
Ertan Akbay
Öz
Heparin-induced thrombocytopenia (HIT) is a difficult clinical presentation to deal with and we know little about the management of these patients. Stopping of heparin is essential in treatment but some patients may need anticoagulation in the follow-up; however, we do not have enough data about the patients with a need of anticoagulant usage. We want to present a myocardial infarction patient who developed type I HIT after exposure to unfractionated heparin with a need of anticoagulation at the same time.
Kaynakça
- 1. Smythe MA, Koerber JM, Mattson JC. The incidence of recognized heparin-induced thrombocytopenia in a large, tertiary care teaching hospital. Chest. 2007;131:1644-9. PMID: 17400685.
- 2. Greinacher A. Heparin-induced thrombocytopenia. N Engl J Med. 2015;373:252-61. PMID: 26535525.
- 3. Çelebi H, Duran C, Çatakoğlu AB, Gülbaran M, Demiroğlu C, Aytekin V. Thrombosed giant right coronary artery aneurysm. Anadolu Kardiyol Derg. 2007;7:350-1. PMID: 17785248.
- 4. Gerbaud E, Cailliez H, Montaudon M. Giant thrombosed aneurysm of the right coronary artery. Arch Cardiovasc Dis. 2014;107:69-71. PMID: 23791586.
- 5. Gülcü E, Sağlam E, Gülcü E, Emiroğlu MY. Giant coronary artery aneurysm in a patient with rheumatoid arthritis. Türk Kardiyol Dern Arş. 2011;39:701-3. PMID: 22257812.
- 6. Salter BS, Weiner MM, Trinh MA, Heller J, Evans AS, Adams DH, et al. Heparin-induced thrombocytopenia: a comprehensive clinical review. J Am Coll Cardiol. 2016;67:2519-32. PMID: 27230048.
- 7. Eichler P, Raschke R, Lubenow N, Meyer O, Schwind P, Greinacher A. The new ID-heparin/PF4 antibody test for rapid detection of heparin-induced antibodies in comparison with functional and antigenic assays. Br J Haematol. 2002;116:887-91. PMID: 11886396.
- 8. Linkins LA, Warkentin TE, Pai M, Shivakumar S, Manji RA, Wells PS, et al. Rivaroxaban for treatment of suspected or confirmed heparin-induced thrombocytopenia study. J Thromb Haemost. 2016;14:1206-10. PMID: 27061271.
- 9. Vavlukis M, Kotlar I, Taravari H, Poposka L, Kedev S. Can rivaroxaban be a drug of choice for treating heparin-induced thrombocytopenia in a patient with pulmonary thromboembolism? Anadolu Kardiyol Derg. 2017;18:77-80. PMID: 28680014.
- 10. Warkentin TE, Pai M, Linkins LA. Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review. Blood. 2017;130:1104-13. PMID: 28646118.
Akut inferior miyokart enfarktüsü seyrinde gelişen heparin ilişkili trombositopeninin yönetimi
Yıl 2020,
, 193 - 196, 12.07.2020
Ali Çoner
,
Sinan Akıncı
,
Ertan Akbay
Öz
Heparin ilişkili trombositopeni (HİT) başa çıkılması zor bir klinik tablodur ve bu hastaların yönetimiyle ilgili bilgimiz sınırlıdır. Heparin’in kesilmesi tedavinin esasıdır ancak bu hastaların bir kısmında antikoagülan kullanım ihtiyacı doğabilir ve takibinde antikoagülan ihtiyacı olan hastalarla ilgili net bir veri bulunmamaktadır. Bu yazımızda anfraksiyone heparin sonrasında tip I HİT gelişen ve aynı zamanda antikoagülan kullanım ihtiyacı bulunan miyokart enfarktüsü hastamızın sunumunu yapmayı amaçladık.
Kaynakça
- 1. Smythe MA, Koerber JM, Mattson JC. The incidence of recognized heparin-induced thrombocytopenia in a large, tertiary care teaching hospital. Chest. 2007;131:1644-9. PMID: 17400685.
- 2. Greinacher A. Heparin-induced thrombocytopenia. N Engl J Med. 2015;373:252-61. PMID: 26535525.
- 3. Çelebi H, Duran C, Çatakoğlu AB, Gülbaran M, Demiroğlu C, Aytekin V. Thrombosed giant right coronary artery aneurysm. Anadolu Kardiyol Derg. 2007;7:350-1. PMID: 17785248.
- 4. Gerbaud E, Cailliez H, Montaudon M. Giant thrombosed aneurysm of the right coronary artery. Arch Cardiovasc Dis. 2014;107:69-71. PMID: 23791586.
- 5. Gülcü E, Sağlam E, Gülcü E, Emiroğlu MY. Giant coronary artery aneurysm in a patient with rheumatoid arthritis. Türk Kardiyol Dern Arş. 2011;39:701-3. PMID: 22257812.
- 6. Salter BS, Weiner MM, Trinh MA, Heller J, Evans AS, Adams DH, et al. Heparin-induced thrombocytopenia: a comprehensive clinical review. J Am Coll Cardiol. 2016;67:2519-32. PMID: 27230048.
- 7. Eichler P, Raschke R, Lubenow N, Meyer O, Schwind P, Greinacher A. The new ID-heparin/PF4 antibody test for rapid detection of heparin-induced antibodies in comparison with functional and antigenic assays. Br J Haematol. 2002;116:887-91. PMID: 11886396.
- 8. Linkins LA, Warkentin TE, Pai M, Shivakumar S, Manji RA, Wells PS, et al. Rivaroxaban for treatment of suspected or confirmed heparin-induced thrombocytopenia study. J Thromb Haemost. 2016;14:1206-10. PMID: 27061271.
- 9. Vavlukis M, Kotlar I, Taravari H, Poposka L, Kedev S. Can rivaroxaban be a drug of choice for treating heparin-induced thrombocytopenia in a patient with pulmonary thromboembolism? Anadolu Kardiyol Derg. 2017;18:77-80. PMID: 28680014.
- 10. Warkentin TE, Pai M, Linkins LA. Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review. Blood. 2017;130:1104-13. PMID: 28646118.