Araştırma Makalesi
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21 ve 22 G EBUS TBNA İğnelerinin Mediastinal ve Hiler LENF nodları Tanısal Değerinin karşılaştırması

Yıl 2020, , 226 - 229, 29.10.2020
https://doi.org/10.30565/medalanya.728239

Öz

Amaç: EBUS TBNA intratorasik lenf nodları için önemli bir tanısal işlemdir. Örnekleme için 21, 22 ve 25 G iğneler kullanılır. 21 G iğnenin iç çapı daha geniş olduğu için daha iyi örneklerin alınması beklenir. Halbu ki, 21 ve 22 G iğneleri kıyaslayan çalışmaların sonuçları çelişkilidir.

Yöntem: Çalışma grubu, 21 G (Grup 1; n=40) ve 22 G (Grup 2; n=40) iğne kullanılarak EBUS TBNA yapılmış hastalardan oluşmuştur. Hasta verileri retrospektif olarak analiz edilmiştir. Tüm örneklemlerde ROSE uygulanmıştır.

Bulgular: 21 G iğnenin sensitivite, spesifite ve tanısal doğruluğu sırasıyla %95, %85 %93 idi. 21 G iğnenin tanısal doğruluğu 22 G iğneye göre daha yüksek idi (93% karşı %80). 22 G göre 21 G iğne ile yapılan işlemde, tanı için daha az örnek yeterli oldu (r=0.03, p<0.05).

Sonuç: 21 G iğnenin tanısal doğruluk oranı, 22 G iğneden daha yüksekti. Bu sonuca göre, 21 G iğneyi tercih etmek daha iyidir. 21 G iğne ile 22 G iğneye göre, daha az sayıda örnek tanı için yeterlidir. 21 G iğne ile elde edilen daha az örnekle teşhis imkanı, ROSE yapan sitopatoloğa zaman avantajı sağlayabilir. Bu avantajdan dolayı ROSE yapılan EBUS TBNA'da 21 G iğneye öncelik verilebilir.

Kaynakça

  • 1. Vaidya PJ, Kate AH, Chhajed PN. Endobronchial ultrasound-guided transbronchial needle aspiration: The standard of care for evaluation of mediastinal and hilar lymphadenopathy. J Cancer Res Ther 2013; 9:549-51. doi: 10.4103/0973- 1482.126430.
  • 2. Herth F, Becker HD, Ernst A. Conventional vs endobronchial ultrasound-guided transbronchial needle aspiration: a randomized trial. Chest 2004;(125):322-5. PMID: 14718460
  • 3. Yasufuku K, Chiyo M, Sekine Y, et al. Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. Chest. 2004; 126:122–128. PMID: 15249452
  • 4. Alsharif M, Andrade RS, Groth SS, Stelow EB, Pambuccian SE. Endobronchial ultrasound-guided transbronchial fine-needle aspiration: The University of Minnesota experience, with emphasis on usefulness, adequacy assessment, and diagnostic difficulties. Am J Clin Pathol. 2008; 130:434–443. doi: 10.1309/BLLQF8KDHWW6MJNQ.
  • 5. Feller-Kopman D, Yung RC, Burroughs F, Li QK. Cytology of endobronchial ultrasound-guided transbronchial needle aspiration: a retrospective study with histology correlation. Cancer Cytopathol. 2009; 117:482–490. doi: 10.1002/cncy.20049.
  • 6. Sun W, Song K, Zervos M, et al. The diagnostic value of endobronchial ultrasound- guided needle biopsy in lung cancer and mediastinal adenopathy. Diagn Cytopathol. 2010; 38:337–342. doi: 10.1002/dc.21195.
  • 7. Minai OA, Dasgupta A, Mehta AC. Transbronchial needle aspiration of central and peripheral lesions; in Bolliger CT, Mathur PN (eds): Interventional Bronchoscopy. Prog Respir. Basel, Karger,2000 pp 66-79.
  • 8. Dasgupta A, Mehta AC.Transbronchial needle aspiration.Clinics in Chest Medicine.1999;20:39-51. PMID: 10205716
  • 9. Schenk DA, Chambers SL, Derdak S, et al. Comparison of the Wang 19 gauge and 22 gauge needles in the mediastinal staging of lung cancer. Am Rev Respir Dis 1993;147: 1251–1258. PMID: 8484639
  • 10. Wang KP, Brower R, Haponik EF, Siegelman S. Flexible transbronchial needle aspiration for staging of bronchogenic carcinoma. Chest 1983; 84:571–576. PMID: 6313305
  • 11. Goldstraw P, Chansky K, Crowley J, Rami-Porta R, Asamura H, Eberhardt WE et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM classification for lung cancer. J Thorac Oncol. 2015;11(1):39–51. doi: 10.1016/j.jtho.2015.09.009.
  • 12. Oki M, Saka H, Kitagawa C, et al. Randomized study of 21-gauge versus 22-gauge endobronchial ultrasound-guided transbronchial needle aspiration needles for sampling histology specimens. J Bronchol Intervent Pulmonology. 2011; 18 (4): 306 – 310. doi: 10.1097/LBR.0b013e318233016c.
  • 13. Saji J, Kurimoto N, Morita K, et al. Comparison of 21-gauge and 22-gauge needles for endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. J Bronchol Intervent Pulmonology. 2011; 18 (3): 239 - 246. doi: 10.1097/LBR.0b013e3182273b41.
  • 14. Lonny B. Y, Jason A, Noah L. et al. Comparison of 21-Gauge and 22-Gauge Aspiration Needle in Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration. Chest 2013; 143(4):1036–1043. doi: 10.1378/chest.12-1205.
  • 15. Griffin AC, Schwartz LE, Baloch ZW. Utility of on-site evaluation of endobronchial ultrasound-guided transbronchial needle aspiration specimens. Cytojournal. 2011; 8:20. doi: 10.4103/1742-6413.90081.
  • 16. Guarize J. Endobronchial ultrasound: From lung cancer diagnosis and staging to translational research. J Bras Pneumol. 2013; 39:119–20. PMID: 23670495

Comparison of 21 G and 22 G EBUS TBNA Needles Diagnostic Value in Mediastinal and Hilar Lymph Nodes

Yıl 2020, , 226 - 229, 29.10.2020
https://doi.org/10.30565/medalanya.728239

Öz

Aim: EBUS TBNA is an important diagnostic procedure for the intrathoracic lymph nodes. 21 G, 22 G and 25 G needles are used for sampling. Better samples can be expected to be taken via 21 G needle, as the inner diameter of 21 G needle is larger. However, the results of the studies comparing 21 G and 22 G needles are controversial.


Methods:
The study population consists of patients with EBUS TBNA performed via 21 G needles (Group 1; n=40) and the patients for whom 22 G needles used (Group 2; n=40). The data of patients were retrospectively analyzed. ROSE was performed for all samples.

Results: The sensitivity, specificity and diagnostic accuracy of the procedure with 21 G needle was 95%, 85%, 93%, respectively. The diagnostic accuracy of 21 G needle was found to be higher than that of 22 G needle (93% versus 80%). In the procedure performed with 21 G needle, fewer samples were sufficient for the diagnosis than 22 G needle (r = 0.03, p <0.05).

Conclusion: The diagnostic accuracy rate of 21 G needle was higher than 22 G needle. According to that result, it is better to prefer 21 G needle. With a 21 G needle, a smaller number of sample was sufficient for diagnosis than a 22 G needle. Diagnostic opportunity with less sample obtained with 21 G needle may provide time advantage to the cytopathologist who performs ROSE. Due to this advantage, in EBUS TBNA with ROSE, 21 G needles can be prioritized.

Kaynakça

  • 1. Vaidya PJ, Kate AH, Chhajed PN. Endobronchial ultrasound-guided transbronchial needle aspiration: The standard of care for evaluation of mediastinal and hilar lymphadenopathy. J Cancer Res Ther 2013; 9:549-51. doi: 10.4103/0973- 1482.126430.
  • 2. Herth F, Becker HD, Ernst A. Conventional vs endobronchial ultrasound-guided transbronchial needle aspiration: a randomized trial. Chest 2004;(125):322-5. PMID: 14718460
  • 3. Yasufuku K, Chiyo M, Sekine Y, et al. Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. Chest. 2004; 126:122–128. PMID: 15249452
  • 4. Alsharif M, Andrade RS, Groth SS, Stelow EB, Pambuccian SE. Endobronchial ultrasound-guided transbronchial fine-needle aspiration: The University of Minnesota experience, with emphasis on usefulness, adequacy assessment, and diagnostic difficulties. Am J Clin Pathol. 2008; 130:434–443. doi: 10.1309/BLLQF8KDHWW6MJNQ.
  • 5. Feller-Kopman D, Yung RC, Burroughs F, Li QK. Cytology of endobronchial ultrasound-guided transbronchial needle aspiration: a retrospective study with histology correlation. Cancer Cytopathol. 2009; 117:482–490. doi: 10.1002/cncy.20049.
  • 6. Sun W, Song K, Zervos M, et al. The diagnostic value of endobronchial ultrasound- guided needle biopsy in lung cancer and mediastinal adenopathy. Diagn Cytopathol. 2010; 38:337–342. doi: 10.1002/dc.21195.
  • 7. Minai OA, Dasgupta A, Mehta AC. Transbronchial needle aspiration of central and peripheral lesions; in Bolliger CT, Mathur PN (eds): Interventional Bronchoscopy. Prog Respir. Basel, Karger,2000 pp 66-79.
  • 8. Dasgupta A, Mehta AC.Transbronchial needle aspiration.Clinics in Chest Medicine.1999;20:39-51. PMID: 10205716
  • 9. Schenk DA, Chambers SL, Derdak S, et al. Comparison of the Wang 19 gauge and 22 gauge needles in the mediastinal staging of lung cancer. Am Rev Respir Dis 1993;147: 1251–1258. PMID: 8484639
  • 10. Wang KP, Brower R, Haponik EF, Siegelman S. Flexible transbronchial needle aspiration for staging of bronchogenic carcinoma. Chest 1983; 84:571–576. PMID: 6313305
  • 11. Goldstraw P, Chansky K, Crowley J, Rami-Porta R, Asamura H, Eberhardt WE et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM classification for lung cancer. J Thorac Oncol. 2015;11(1):39–51. doi: 10.1016/j.jtho.2015.09.009.
  • 12. Oki M, Saka H, Kitagawa C, et al. Randomized study of 21-gauge versus 22-gauge endobronchial ultrasound-guided transbronchial needle aspiration needles for sampling histology specimens. J Bronchol Intervent Pulmonology. 2011; 18 (4): 306 – 310. doi: 10.1097/LBR.0b013e318233016c.
  • 13. Saji J, Kurimoto N, Morita K, et al. Comparison of 21-gauge and 22-gauge needles for endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. J Bronchol Intervent Pulmonology. 2011; 18 (3): 239 - 246. doi: 10.1097/LBR.0b013e3182273b41.
  • 14. Lonny B. Y, Jason A, Noah L. et al. Comparison of 21-Gauge and 22-Gauge Aspiration Needle in Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration. Chest 2013; 143(4):1036–1043. doi: 10.1378/chest.12-1205.
  • 15. Griffin AC, Schwartz LE, Baloch ZW. Utility of on-site evaluation of endobronchial ultrasound-guided transbronchial needle aspiration specimens. Cytojournal. 2011; 8:20. doi: 10.4103/1742-6413.90081.
  • 16. Guarize J. Endobronchial ultrasound: From lung cancer diagnosis and staging to translational research. J Bras Pneumol. 2013; 39:119–20. PMID: 23670495
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular İç Hastalıkları
Bölüm Araştırma Makalesi
Yazarlar

Hulya Dirol 0000-0002-7712-6467

Ruşen Uzun 0000-0001-6575-5066

Canan Sadullahoğlu 0000-0001-8532-0289

Yayımlanma Tarihi 29 Ekim 2020
Gönderilme Tarihi 28 Nisan 2020
Kabul Tarihi 13 Temmuz 2020
Yayımlandığı Sayı Yıl 2020

Kaynak Göster

Vancouver Dirol H, Uzun R, Sadullahoğlu C. Comparison of 21 G and 22 G EBUS TBNA Needles Diagnostic Value in Mediastinal and Hilar Lymph Nodes. Acta Med. Alanya. 2020;4(3):226-9.

9705 

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