Evaluation of Prognostic Factors In Nasopharyngeal Cancers

Yıl 2017, Cilt: 1 Sayı: 2, 72 - 76, 15.07.2017

Rüstem Hasanov Hüseyin Günizi , Kenan Güney

https://doi.org/10.30565/medalanya.314531

Öz

Aim: We aimed to examine
prognostic factors that affect the survival of patients with nasopharyngeal
cancer (NPC) who were diagnosed and treated in our clinic.

Methods: Patients with
nasopharyngeal cancer, who were diagnosed and treated in our clinic between 2009-2013,
were examined retrospectively.

Results: In our study, 33
patients were male (%73.3), 12 patients were female (%26.6), and  male/female ratio was 2.75. Mean age was
50,8; the youngest patient was 14 and the oldest one was 84 years old.  The most common presenting cause was cervical
lymph node metastasis (%66,7). %66,6 of our patients had advanced stage tumor
(Stage 3-4). Longer survival was detected in low T-stage patients, whereas no
relation was determined between N-stage and survival. No statistical relation
was determined between histopathological types and 2-year survival. Longer
survival was observed in young age group and male patients; however, this was
not statistically significant.

Conclusion: Younger age are good
prognostic factors, however, the advanced T and N stages at diagnosis are poor
prognostic factors. Therefore, early diagnosis is important in terms of
treatment and survival.

Anahtar Kelimeler

Nasopharynx, Prognostic factors, Retrospective

Nazofaringeal Kanserlerde Prognostik Faktörlerin Değerlendirilmesi

Öz

 Amaç: Kliniğimizde teşhis
ve tedavi edilen nazofaringeal kanserli (NPC) hastaların hayatta kalmasını
etkileyen prognostik faktörleri incelemektir.

Yöntemler: Kliniğimizde
2009-2013 yılları arasında teşhis ve tedavi edilen nazofaringeal kanserli
hastalar geriye dönük olarak incelendi.

Bulgular: Çalışmamızda 33
hasta erkek (% 73.3), 12 hasta kadın (% 26.6), erkek / kadın oranı 2.75 idi.
Ortalama yaş 50,8; En genç hasta 14 ve en yaşlısı 84 yaşında idi. En sık
görülen neden servikal lenf nodu metastazı (% 66,7) idi. Hastalarımızın%
66,6'sında ileri evre tümör vardı (Evre 3-4). Düşük T evresi hastalarında daha
uzun sağkalım süresi saptanırken, N-evresi ile sağkalım arasında ilişki
saptanmadı. Histopatolojik tiplerle 2 yıllık sağkalım arasında istatistiksel
olarak bir ilişki saptanmadı. Genç yaş grubu ve erkek hastalarda daha uzun
sağkalım süresi gözlemlendi fakat bu istatistiksel olarak anlamlı değildi.

Sonuç: Genç yaş iyi
prognostik faktörlerdir, ancak tanıdaki ilerlemiş T ve N evreleri kötü
prognostik faktörlerdir. Bu nedenle erken teşhis, tedavi ve sağkalım açısından
önemlidir.

Anahtar Kelimeler

nazofarenks, prognostik faktörler, retrospektif

Kaynakça

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