Transcranial Magnetic stimulation in Psychiatry: Past, Current and Future

Yıl 2021, Cilt: 5 Sayı: 2, 107 - 108, 30.08.2021

Burak Yuluğ Ahmet Aslan

https://doi.org/10.30565/medalanya.985758

Öz

Transcranial Magnetic Stimulation (rTMS) is a novel non-invasive neuromodulation method applied via a coil to the skull surface of the patient stimulating relevant brain regions. Replicating data suggest the therapeutic role of repetitive transcranial magnetic stimulation (rTMS) in many psychiatric diseases though there are limited human neuroprotective data. Here we aimed to evaluate the therapeutic role of rTMS from a multifaceted perspective, including its effects on the neuroplasticity and neuroprotection processes. As a conclusion, rTMS seems to offer a potential for neuroprotective therapy.

Anahtar Kelimeler

Transcranial Magnetic Stimulation;, Neuroprotection;, Psychiatric Diseases;, Neuroplasticity, Neuroplasticity;

Psikiyatride Transkraniyal Manyetik Uyarım: Geçmiş, Şimdi ve Gelecek

Öz

Transkraniyal Manyetik Uyarım (TMU), hastanın kafatası yüzeyine bir bobin aracılığıyla uygulanarak ilgili beyin bölgelerini uyaran yeni bir non-invaziv nöromodülasyon yöntemidir.insan çalışmalarında nöroprotektif etkisine dair kanıtlar sınırlı olsa da, yinelenen veriler, birçok psikiyatrik bozuklukta TMU’ nın terapötik rol oynadığını düşündürmektedir. Bu yazıda nöroplastisite ve nöroproteksiyonun süreçler üzerindeki etkileri de dahil olmak üzere, çok yönlü bir bakış açısıyla TMU'nın terapötik etkisini araştırdık. Sonuç olarak, TMU, nöroprotektif tedavi için bir potansiyel sunuyor gibi görünmektedir.

Anahtar Kelimeler

Transkraniyal Manyetik Uyarım;, Nöroproteksiyon;, Psikiyatrik Hastalıklar;, Nöroplastisite

Kaynakça

• 1. Eschweiler G.W. (2003) Entwicklung der transkraniellen Magnetstimulation (TMS). In: Eschweiler G.W., Wild B., Bartels M. (eds) Elektromagnetische Therapien in der Psychiatrie. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57370-5_16
• 2. Facharztwissen Psychiatrie, Psychosomatik und Psychotherapie (2017). Frank Schneider. Springer-Verlag GmbH Deutschland. https://doi.org/10.1007/978-3-662-50345-4
• 3. Yulug B. Neuroprotective treatment strategies for poststroke mood disorders: A minireview on atypical neuroleptic drugs and selective serotonin re-uptake inhibitors. Brain Res Bull. 2009 Sep 28;80(3):95-9. doi: 10.1016/j.brainresbull.2009.06.013. Epub 2009 Jul 1. PMID: 19576272
• 4. Caglayan B, Kilic E, Dalay A, et al. Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury in mice. Mol Biol Rep. 2019;46(1):241-250. doi:10.1007/s11033-018-4465-4
• 5. Lapchak, Paul A., and John H. Zhang, eds. Neuroprotective therapy for stroke and ischemic disease. Switzerland: Springer International Publishing, 2017. doi:10.1007/978-3-319-45345-3
• 6. Yulug B, Hanoglu L, Tavli AM, Yılmaz NH, Kılıc E. The Brain Protective Effect of rTMS (Repetitive Transcranial Magnetic Stimulation) in Depression: A Mini-Review in Animal Studies. Med Chem. 2016;12(6):500-505. doi:10.2174/1573406411666151005110321
• 7. Yuluğ B, Ozan E, Kilic E. Brain-derived neurotrophic factor polymorphism as a genetic risk for depression? A short review of the literature. J Neuropsychiatry Clin Neurosci. 2010 Winter;22(1):123.E5-6. doi: 10.1176/jnp.2010.22.1.123.e5
• 8. Yulug B, Hanoglu L, Khanmammadov E, et al. Beyond The Therapeutic Effect of rTMS in Alzheimer's Disease: A Possible Neuroprotective Role of Hippocampal BDNF? : A Minireview. Mini Rev Med Chem. 2018;18(17):1479-1485. doi:10.2174/1389557517666170927162537