The relation between serum 25-hydroxy vitamin D levels and recurrent wheezing in preschool children

Yıl 2019, Cilt: 12 Sayı: 1, 88 - 95, 28.04.2019

Feryal Karahan , Cem Hasan Razi Ayşe Derya Buluş , Nesibe Andıra

https://doi.org/10.26559/mersinsbd.438568

Öz

Aim: To
investigate the effect of 25-hidroxy D vitamin, one of the environmental
factors, on recurrent wheezing episodes in pre-school children. Methods: This
research was conducted on77 patients who had recurrent wheezing attacks and were
followed by the pediatric allergy department of Keçiören Training and Research
Hospital, and other 74 healthy children attending the pediatric clinic with the
same age range as the control group. 

Medical
charts of the patients and control group were reviewed to determine the weight, height, delivery method, their mother’s age, duration of vitamin D usage, nutrition history and
the time of the first wheezing attacks of the patient group, number of wheezing
attacks and the number of hospitalization due to the recurrent wheezing. Serum calcium, phosphorus, and 25-hidroxy
vitamin D and levels were evaluated in both groups. Results: Fifty-four
(70%) of the patient group were male and 23 (29.9%) of them were female. The
mean age was 29.5±17.9 months. Forty-four (59.5%) of the control group were
male and 30 (40.5%) of them were female. The mean age was 31.7±18.1
months. There was no relation between serum vitamin D levels, the date of first
wheezing attack, total number of wheezing attacks and number of
hospitalizations in the patient group. It was found that the number of wheezing
attacks of the patients with positive predictive index for asthma was
significantly higher than those with negative asthma predictive index but there
was no relation with serum 25-hydroxy vitamin D levels. Conclusions: In this research, no relation was found between serum
vitamin D levels and the date of first wheezing attack, total amount of
wheezing attacks and the number of hospitalizations due to these attacks. 

Anahtar Kelimeler

Preschool Child, Recurrent Wheezing, Vitamin D

Okul öncesi çocuklarda serum 25-hidroksi D vitamin düzeyleri ile tekrarlayan hışıltı arasındaki ilişki

Öz

Amaç: Çevresel faktörlerden biri olan 25-hidroksi D
vitamininin okul öncesi çocuklarda tekrarlayan hışıltı ataklarına etkisini
araştırmak. Yöntem: Çalışmaya
Keçiören Eğitim ve Araştırma Hastanesi Çocuk Alerji Polikliniği’nde tekrarlayan
vizing atağı nedeni ile takipli 77 hasta, kontrol grubuna benzer yaş grubunda
olan çocuk sağlığı polikliniğine başvuran 74 sağlıklı çocuk alındı. Hasta ve
kontrol grubunun dosyaları incelenerek çocukların ağırlık, boy, doğum şekli,
anne yaşı, D vitamini kullanma süresi, beslenme öyküsü ve ayrıca hasta
grubundakilerin ilk vizing atak zamanı, vizing atak sayısı ve vizing nedeniyle
hastaneye yatış sayısı belirlendi. Her iki grupta serum kalsiyum, fosfor ve
25-Hidroksi D vitamini düzeyleri çalışıldı. Bulgular: Hasta grubunun 54’ü (%70.1) erkek, 23’ü
(%29.9) kız, ortalama yaşları 29.5±1.9 ay olup kontrol grubunun 44’ü
(%59.5) erkek, 30’u (%40.5) kız ve ortalama
yaşları 31.7±18.1 aydı. Hasta grubunda serum D vitamini düzeyi ile ilk
vizing atak zamanı, vizing atak sayısı ve hastaneye yatış sayıları arasında bir
ilişki bulunmadı. Hasta grupta astım prediktif indeksi pozitif olanların vizing
atak sayısının negatif olan gruptan anlamlı olarak daha fazla olduğu ancak serum 25
hidroksi vitamin D vitamini düzeyi ile arasında
ilişki olmadığı saptandı. Sonuç: Çalışmamızda serum D vitamini düzeyi ile ilk vizing atak zamanı,
vizing atak sayısı ve hastaneye yatış sayısı arasında ilişki saptanmamıştır. 

Anahtar Kelimeler

Okul Öncesi Çocuklar, Tekrarlayan Vizing, Vitamin D

Kaynakça

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