Diffuse lamella keratitis: diagnosis and treatment methods

Yıl 2019, Cilt: 12 Sayı: 1, 126 - 135, 28.04.2019

Cüneyt Karaarslan

https://doi.org/10.26559/mersinsbd.513300

Öz

Developing after refractive surgery, Diffuse Lamellar
Keratitis is a complication that appears as small gray-white corneal spots in
the periphery. It is mostly unilateral (one-eye) and distant to the visual
axis. If it goes unnoticed at initial stages, and if appropriate treatment is
not applied, it may cause severe visual impairment. Refractive surgery is
especially preferred by active and young population to be released of glasses
and lens dependence, and is becoming widely applied with each passing day. In
this paper, the purpose is to determine the early diagnosis and treatment
modalities for Diffuse Lamellar Keratitis, and to examine current approaches
for the prevention of permanent visual impairment, which may lead to
progressive and irreversible corneal and visual damage.

Anahtar Kelimeler

Refractive Surgery, Diffus Lamellar Keratit, Permanent Corneal Necrosis, loss of vision

Diffüz lamellar kretatit: Tanı ve tedavi yöntemleri

Öz

Refraktif
cerrahi sonrası gelişen diffüz lameller keratit, çoğunlukla unilateral (tek
gözde), görme ekseninden uzak, periferal yerleşimli küçük gri-beyaz korneal
noktacıklar şeklinde ortaya çıkan bir komplikasyon tablosudur. Başlangıç
evrelerde farkına varılmaz ve uygun tedavi ile önlem alınmazsa, ileride ciddi
görme kaybına neden olabilmektedir. Özellikle aktif ve genç nüfusun, gözlük ve
lens bağımlılığından kurtulmak için tercih ettiği refraktif cerrahi gün
geçtikçe daha yoğun bir şekilde uygulanmaktadır. Bu yazıda; ilerleyici ve geri
dönüşümsüz kornea ve görme hasarına neden olabilecek, diffüz lameller
keratitin, erken tanısı ve tedavisi ile ileride gelişebilecek kalıcı görme
kaybının önlenmesi için güncel yaklaşımların ortaya konulması amaçlanmıştır.

Anahtar Kelimeler

Refraktif Cerrahi, Diffüz Lameller Keratit, Korneanın Kalıcı Nekrozu

Kaynakça

• 1. Kymionis GD ve ark. Diffuse lamellar keratitis after corneal crosslinking in a patient with post-laser in situ keratomileusis corneal ectasia - Elsevier Journal of Cataract & …, 2007 – 2135-2137
• 2. Schallhorn SC ve ark, Avoidance, Recognition, and Management of LASIK Complications - Elsevier American journal of …, 2006 - 733-739
• 3. Stulting RD ve ark, The epidemiology of diffuse lamellar keratitis - Cornea, 2004, - 680-688
• 4. Steck Rp ve ark, Diffuse lamellar keratitis 14 years after laser in situ keratomileusis induced by an eyelash in the flap interface - Elsevier JCRS Online Case Reports, 2018 – 69-70
• 5..Dawson DG ve ark, Interface fluid syndrome in human eye bank corneas after LASIK : causes and pathogenesis – Ophtalmology, 2007 – Elsevier - 1848-1859.
• 6. Iovieno A ve ark, Diffuse lamellar keratitis 8 years after LASIK caused by corneal epithelial defect - Journal of Cataract & …, 2011 - 418-419
• 7. Reinstein DZ ve ark, Incidence and Outcomes of Sterile Multifocal Inflammatory Keratitis and Diffuse Lamellar Keratitis After SMILE - Journal of Refractive, 2018- 751-759
• 8. Mimouni M ve ark, , Incidence, Indications, and Outcomes of Eyes Needing Early Flap Lifting After LASIK - Cornea -1118-1123
• 9. Noda-Tsuruya T ve ark, Risk factors for development of diffuse lamellar keratitis after laser in situ keratomileusis - Journal of refractive, 2004 - 72-75. 10. Castoro CJ, Causes of diffuse lamellar keratitis - Ophthalmology, 2003 - aaojournal.org – 873-874
• 10. Castoro CJ, Causes of diffuse lamellar keratitis - Ophthalmology, 2003 - aaojournal.org – 873-874
• 11. Zhao J, Diffuse lamellar keratitis after small-incision lenticule extraction, Journal Cataract refract surg, 2015 – 400-407
• 12. Shovlin JP, A corneal conundrum: are these post-LASIK complications clinically distinct entities, or a continuum? - Review of Optometry, 2014 - 68
• 13. Mah FS ve ark, Role of topical fluoroquinolones on the pathogenesis of diffuse lamellar keratitis in experimental in vivo studies - Journal of Cataract & …, 2006 - 264-268.
• 14, Gritz DC, LASIK interface keratitis: epidemiology, diagnosis and care - Current opinion in ophthalmology, 2011 - 251-255.
• 15. Alió JL, Azar DT, Management of complications in refractive surgery, 2nd ed, Springer 2018
• 16 Linebarger EJ ve ark, Diffuse lamellar keratitis: diagnosis and management- Journal of Cataract & …, 2000 – Elsevier- 1072-1077
• 17. Buxey K, Delayed onset diffuse lamellar keratitis following enhancement LASIK surgery- Clinical and Experimental Optometry, 2004 - 102-106
• 18.Jeng BH, Relapsing Diffuse Lamellar Keratitis After Laser In Situ KeratomileusisAssociated With Recurrent Erosion Syndrome - Archives of …, 2004- 396-398.
• 19. Murueta-Goyena Ane, Visual outcomes and management after corneal refractive surgery : A review – Journal of Optometry, 2018 – 121-129
• 20. Gritz DC, LASIK interface keratitis: epidemiology, diagnosis and care- Current opinion in ophthalmology, 2011 – 251-255
• 21. Cheung AY ve ark, Late-onset diffuse lamellar keratitis following laser in situ keratomileusis- Canadian Journal of, 2018- 435-437
• 22. Gris O ve ark, Diffuse lamellar keratitis and corneal edema associated with viral keratoconjunctivitis 2 years after laser in situ keratomileusis - Journal of Cataract & Refractive …, 2004- 1366-1370