Ağır metal maruziyetinde disbiyozis ve probiyotikler

Yıl 2021, Cilt: 14 Sayı: 1, 146 - 158, 30.04.2021

Kevser Başoğlu Aylin Ayaz

https://doi.org/10.26559/mersinsbd.709342

Öz

Modern yaşamda ağır metallerin artan kullanımı, ağır metal maruziyetinde önemli ölçüde artışa sebep olmuştur. Ağır metallerin doğada yüksek kalıcılıkları ve yaygın maruziyet sebebiyle bu durum ağır metal maruziyetini önemli bir halk sağlığı problemi haline getirmiştir. Ağır metaller intestinal mikrobiyotanın yapısını ve çeşitliliğini etkileyerek disbiyozise sebep olmaktadır. Ağır metal maruziyetinin sebep olduğu disbiyozisin; oksidatif stres, karaciğer hasarı ve obezite gibi çeşitli sağlık sorunları ile ilişkili olabileceği bildirilmiştir. Probiyotiklerin ağır metallerin neden olduğu hasarı azaltmada, mikrobiyotanın yeniden dengelenmesinde ve sağlığının sürdürülmesinde umut verici olduğu belirtilmektedir. Bu derlemenin amacı, ağır metal maruziyetinin intestinal mikrobiyotaya olası etkilerini, bu etkilerin metabolik sonuçlarını ve probiyotik takviyesinin ağır metal toksisitesini iyileştirme potansiyelini değerlendirmektir

Anahtar Kelimeler

ağır metaller, halk sağlığı, probiyotikler, disbiyozis

Dysbiosis in heavy metal exposure and the probiotics

Öz

The increasing use of heavy metals in modern life has led to a significant increase in heavy metal exposure. Heavy metals have become an important public health problem due to their high persistence and widespread exposure in nature. Heavy metals cause dysbiosis by affecting the structure and diversity of the intestinal microbiota. Exposure to heavy metals is an important public health problem due to their high persistence and widespread exposure in nature. Dysbiosis in microbiota caused by heavy metal exposure has been reported that it may be associated with various health problems such as oxidative stress, liver damage, and obesity. It is stated that probiotics are promising in reducing the damage caused by heavy metals, rebalancing microbiota and maintaining their health. The purpose of this review is to evaluate the potential effects of heavy metal exposure to the intestinal microbiota, the metabolic results of these effects and the potential of the probiotic supplement to improve heavy metal toxicity.

Anahtar Kelimeler

Heavy metals, public health, probiotics, dysbiosis

Kaynakça

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