Zoonotic Potential of Aeromonas veronii Isolated from Wild Leuciscus cephalus and Cyprinus carpio: A Public Health Perspective

Öz

Aeromonas veronii is an emerging zoonotic pathogen implicated in septicemia and ulcerative diseases in freshwater fish. Increasing reports of its presence in aquatic environments and its pathogenic potential in both humans and animals highlight the need for active surveillance. This study aimed to determine the prevalence bacteriological tissue tropism, and antimicrobial resistance of A. veronii in two commonly consumed freshwater fish species Cyprinus carpio and Leuciscus cephalus from natural habitats. A total of 75 fish samples were collected from the Tigris River in December 2024. Tissue tropism was assessed bacteriologically by isolating the bacterium from liver, kidney, gills, and fins. A. veronii was detected in 61.3% of fish, predominantly in liver and kidney tissues. Isolates exhibited high resistance to ampicillin (90.9%) and oxytetracycline (97%), while remaining moderately susceptible to enrofloxacin and streptomycin (72.7%). These findings indicate a high prevalence of multidrug-resistant A. veronii in wild freshwater fish, emphasizing potential public health risks and the need for improved monitoring and responsible antibiotic use.

Anahtar Kelimeler

• Aquatic zoonotic agent
• Cyprinus carpio
• Leuciscus cephalus
• MALDI-TOF

Destekleyen Kurum

This study has received no financial resources or support from any institution.

Etik Beyan

The authors declare that all ethical rules were followed throughout the research.

Yabani Leuciscus cephalus ve Cyprinus carpio'dan İzole Edilen Aeromonas veronii'nin Zoonotik Potansiyeli: Bir Halk Sağlığı Perspektifi

Öz

Aeromonas veronii, tatlı su balıklarında septisemi ve ülseratif hastalıklara neden olan yeni ortaya çıkan bir zoonotik patojendir. Sucul ortamlardaki varlığına ve hem insanlarda hem de hayvanlarda patojenik potansiyeline dair artan raporlar, aktif gözetim ihtiyacını vurgulamaktadır. Bu çalışma, doğal yaşam alanlarında yaygın olarak tüketilen iki tatlı su balığı türü olan Cyprinus carpio ve Leuciscus cephalus'ta A. veronii'nin yaygınlığını, doku tropizmini ve antimikrobiyal direncini araştırmayı amaçlamaktadır. Aralık 2024'te Dicle Nehri'nden toplam 75 balık örneği toplanmıştır. Bakteriyel tanımlama, kültür tabanlı yöntemler ve MALDI-TOF kütle spektrometrisi kullanılarak gerçekleştirilmiştir. A. veronii, 46 örnekten (%61,3) izole edilmiş olup, en yüksek tespit oranları karaciğer ve böbrek dokularında elde edilmiştir. İzolatlar ampisiline (%90,9), amoksisiline (%90,9), eritromisine (%97) ve oksitetrasikline (%97) karşı güçlü dirençliydi; ancak enrofloksasine (%72,7), streptomisine (%72,7), siprofloksasine (%59) ve gentamisine (%59) karşı duyarlı kaldılar. Bu bulgular, tatlı su yabani balıklarında çoklu ilaca dirençli A. veronii'nin yüksek yaygınlığına işaret etmekte olup, kirlenmiş su organizmalarının tüketimi yoluyla olası halk sağlığı sonuçlarını göstermektedir. Bu tehditlerle mücadele etmek için su ekosistemlerinde antibiyotiklerin daha iyi izlenmesi ve akıllıca kullanılması esastır.

Anahtar Kelimeler

• Sucul zoonotik ajan
• Cyprinus carpio
• Leuciscus cephalus
• MALDI-TOF

Destekleyen Kurum

Bu çalışma herhangi bir kurumdan maddi destek veya kaynak almamıştır.

Etik Beyan

Yazarlar araştırma boyunca tüm etik kurallara uyulduğunu beyan ederler.

Kaynakça

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