Prostat Radyofrekans Termoterapinin Alfa Bloker Tedaviye Dirençli Noktürisi Olan BPO' lu Yaşlı Hastalarda Etkinliği ve Güvenliği: Gözlemsel Çalışma

Öz

Amaç: Bu çalışmanın amacı yaşlı hastalarda bipolar radyofrekans prostat termoterapi yönteminin nokturi şikayeti üzerine etkinliğini ve güvenliğini incelemektir. Gereç ve Yöntemler: Altmış beş yaş üstü ve dirençli nokturi şikayeti olan 100 hastanın işlem sonrası sonuçları incelendi. Hastaların, işlem öncesi Qmax, prostat volümleri, işeme sonrası rezidü miktarı, IPSS skorları, nokturi frekansı ve Nocturia Quality of Life sorgulama formu kaydedilip işlem sonrası 3. ay sonuçları ile karşılaştırıldı. Bulgular: Nokturi sıklığı ortalama 4,1 (2-13) kez görülürken işlem sonrası bu sayı 2,1 (0-10)’ya geriledi (p=0,002). N-QOL yaşam kalitesi formunda 1,70±0,7 oranında ve gece idrara çıkmanın vermiş olduğu rahatsızlıklarda anlamlı iyileşme görüldü (p<0,001). Hastaların işlem öncesinde yaşam kalitesi indeksi skoru ortalama 4,2 (1-4) iken üçüncü ayda 2,5 (1-5) olarak hesaplandı. Sonuç: Bu tedavi yönteminin 65 yaş üzeri hastalarda nokturi açısından anlamlı derecede iyileşme, hastaların yaşam kalitelerine pozitif yönde etki sağladığı görüldü. Yaşlı hastalarda yan etkisi olabilen veya kullanımı uygun olmayan tedavilere göre daha etkili ve güvenilir bir yöntem olabileceği düşünülmektedir

Anahtar Kelimeler

• Noktüri
• yaşlı
• radyofrekans
• termoterapi
• prostat

Efficacy and Safety of Prostate Radiofrequency Thermotherapy in Elderly Patients with BPO and Nocturia Resistant to Alpha-Blocker Therapy: An Observational Study

Öz

Aim: The purpose of this study is to investigate the effectiveness of the prostate bipolar radiofrequency thermotherapy method on the complaint of nocturia and its safety in elderly patients. Material and Methods: The post-procedural results of 100 patients over the age of 65 with complaints of refractory nocturia were examined. The patients' pre-procedural Qmax values, prostate volumes, postvoid residual amounts, IPSS scores, frequency of nocturia, and associated quality of life questionnaire scores were recorded and compared with the results at the 3rd month after the procedure. Results: The pre-procedural and post-procedural nocturia frequencies of the patients were consecutively 4.1 (2-13) times and 2.1 (0-10)times (p=0.002). There were significant improvements in the N-QOL scores of the patients by 1.70±0.7 and in their discomfort caused by voiding at night (p<0.001). The mean QOL score of the patients before the procedure was 4.2 (1-4), whereas it was calculated as 2.5 (1-5) 3 months after the procedure. Conclusion: It was observed that this treatment method provided a significant improvement in terms of nocturia in patients over the age of 65 and a positive effect on their quality of life. It is thought that it can be a more effective and safer method in comparison to treatments that can have side effects or are not suitable for elderly patients.

Anahtar Kelimeler

• Nocturia
• elderly
• radiofrequency
• thermotherapy
• prostate

Kaynakça

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