Evaluation of Inflammatory Biomarkers in Predicting Strangulation in Incarcerated Inguinal Hernias in Adult Patients Admitted to the Emergency Department; Cross-Sectional Study

Öz

Aim: It is very important to determine the diagnosis of strangulation quickly and with high accuracy in patients presenting with incarcerated hernia. Early diagnosis of strangulation reduces the rate of bowel resection. The objective of our study was to assess the effectiveness and consistency of recently established indices, namely neutrophil lymphocyte ratio (NLR), the systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune-inflammation value (PIV) in predicting the occurrence of strangulation in incarcerated hernias. Material and Methods: Our study included patients over the age of 18 who presented to the emergency department with abdominal pain between 01.01.2020 and 01.01.2023 and were diagnosed with incarcerated inguinal hernia according to the examination results. There were two groups of patients with strangulated inguinal hernia (SIH) and non-strangulated inguinal hernia (NSIH). Receiver Operating Characteristic (ROC) analysis was used to define the cut-off in diagnostic value values. Results: A total of 128 patients (39 SIH and 89 NSIH) were enrolled. Neutrophil lymphocyte ratio, There was determined to be acceptable diagnostic power for SIH detection using SII, SIRI, and PIV (AUC:0.738-0.765). Conclusion: Biomarkers such as SII, SIRI, PIV and NLR can be utilized for prediction SIH in incarcerated hernias.

Anahtar Kelimeler

• Pan-immune-inflammation value
• incarcerated hernia
• neutrophil lymphocyte ratio
• systemic immune-inflammation index
• strangulated inguinal hernia
• systemic inflammation response index

Acil Servise Başvuran Erişkin Hastalarda İnkarsere İnguinal Hernilerde Strangülasyonun Öngörülmesinde İnflamatuar Biyobelirteçlerin Değerlendirilmesi; Kesitsel Çalışma

Öz

Amaç: İnkarsere herni ile başvuran hastalarda strangulasyon tanısının hızlı ve yüksek doğrulukla belirlenmesi oldukça önemlidir. Strangulasyonun erken tanısı bağırsak rezeksiyonu azalmaktadır. Çalışmamızda nötrofil lenfosit oranı (NLR) ile birlikte sistemik immüninflamasyon indeks (SII), sistemik inflamasyon yanıt indeksi (SIRI), pan-immün- inflamasyon değeri (PIV) gibi yeni tanımlanan indekslerin inkarsere hernilerde stangulasyonu öngörmedeki gücü ve güvenirliliği değerlendirme amaçlandı. Gereç ve Yöntemler: Çalışmamız acil servise 01.01.2020 ile 01.01.2023 tarihleri arasında karın ağrısı ile başvuran ve tetkik sonucuna göre inkarsere inguinal herni tanısı konulan 18 yaş üstü hastalar dahil edildi. Boğulmuş kasık fıtığı (SIH) ve boğulmamış kasık fıtığı (NSIH) olmak üzere iki grup hasta vardı. Tanısal değer ölçümlerindeki kesme noktası, Alıcı İşletim Karakteristiği (ROC) analizi kullanılarak belirlendi. Bulgular: Toplam 128 hasta (SIH:39 ve NSIH:89) kaydedildi. Nötrofil lenfosit oranı, SII, SIRI ve PIV'in SIH tespitinde kabul edilebilir tanısal güce sahip olduğu bulundu (AUC:0,738-0,765). Sonuç: İnkarsere hernilerde SIH’ı öngörmede SII, SIRI, PIV ve NLR gibi biyomarkırlar kullanılabilir

Anahtar Kelimeler

• Pan-immün-inflamatuar değeri
• inkarsere herni
• nötrofil lenfosit oranı
• strangule inguinal herni
• sistemik immüninflamatuar indeks
• sistemik inflamasyon yanıt indeksi

Kaynakça

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