Araştırma Makalesi

Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures

Cilt: 10 Sayı: 1 29 Nisan 2026
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Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures

Öz

Aim: Vertebral compression fractures are a common cause of pain and disability in the elderly population. Percutaneous vertebroplasty is an established minimally invasive intervention, yet the optimal approach (unilateral or bilateral) remains controversial. This study focused on comparing the clinical and radiological outcomes of unilateral versus bilateral percutaneous vertebroplasty in patients with painful osteoporotic vertebral compression fractures. Material and Methods: A retrospective review was conducted on 203 patients (73 males, 130 females; mean age 65.3 ± 8.9 years) with 309 treated vertebral levels from 2014 to 2024. Patients underwent either unilateral (n = 104) or bilateral (n = 99) PVP. Pain and disability were assessed using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI), while radiological outcomes included anterior vertebral height restoration and segmental Cobb angle correction. Results: Both approaches provided significant pain relief and functional improvement. Bilateral PVP achieved lower postoperative VAS (1.9 vs 2.1, p = 0.040) and ODI scores (23.1% vs 26.3%, p = 0.020) compared to unilateral PVP. Radiologically, bilateral procedures resulted in superior anterior height restoration (25.8% vs 19.2%, p = 0.001) and greater Cobb angle correction (9.1° vs 6.4°, p = 0.001). Cement leakage rates were similar in both groups (≈4%), with no symptomatic complications. Conclusion: Unilateral and bilateral PVP are both safe and effective for osteoporotic VCFs. Bilateral PVP demonstrated superior radiological correction, whereas unilateral PVP remains advantageous due to reduced operative burden. Treatment decisions should be individualized based on patient anatomy and procedural goals.

Anahtar Kelimeler

Kaynakça

  1. Ateş A, Gemalmaz HC, Deveci MA, Şimşek SA, Çetin E, Şenköylü A. Comparison of effectiveness of kyphoplasty and vertebroplasty in patients with osteoporotic vertebra fractures. Acta Orthop Traumatol Turc 2016;50(6):619-622. http://doi.org/10.1016/j.aott.2016.10.001
  2. Qiao Y, Wang X, Liu Y, Hu J, Yuan FH, Zhao ZG. Comparison of unilateral and bilateral percutaneous kyphoplasty for osteoporotic vertebral compression fractures. J Pain Res 2023;16:1813-1823. http://doi.org/10.2147/JPR.S413048
  3. Chen JF, Lee ST, Lui TN, Wu CT, Liao CC. Percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures: A preliminary report. Chang Gung Med J 2002;25(5):306-314
  4. McKiernan F, Faciszewski T, Jensen R. Quality of life following vertebroplasty. J Bone Joint Surg Am 2004;86(12):2600-2606. http://doi.org/10.2106/00004623-200412000-00007
  5. Zhang LG, Gu X, Zhang HL, Zhang QG, Cai XB, Tao K. Unilateral or Bilateral Percutaneous Vertebroplasty for Acute Osteoporotic Vertebral Fracture: A Prospective Study. J Spinal Disord Tech 2015;28(2):E85-E88. http://doi.org/10.1097/BSD.0000000000000064
  6. Galibert P, Deramnd H, Rosat P, Le Gars D. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie 1987;33:166-168
  7. Kobayashi K, Shimoyama K, Nakamura K, Murata K. Percutaneous vertebroplasty immediately relieves pain of osteoporotic vertebral compression fractures and prevents prolonged immobilization of patients. Eur Radiol 2005;15(2):360-367. http://doi.org/10.1007/s00330-004-2536-8
  8. Purkayastha S, Gupta AK, Kapilamoorthy TR, Kesavadas C, Thomas B, Krishnamoorthy T, et al. Percutaneous vertebroplasty in the management of vertebral lesions. Neurol India 2005;53(2):167-173

Ayrıntılar

Birincil Dil

İngilizce

Konular

Beyin ve Sinir Cerrahisi (Nöroşirurji)

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

29 Nisan 2026

Gönderilme Tarihi

30 Eylül 2025

Kabul Tarihi

12 Mart 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 10 Sayı: 1

Kaynak Göster

APA
Aydın, L., Sarıgül, B., Kartum, T. A., Öndüç, G. G., Şahin, S. A., & Ramazanoğlu, A. F. (2026). Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures. Medical Journal of Western Black Sea, 10(1), 157-163. https://doi.org/10.29058/mjwbs.1793536
AMA
1.Aydın L, Sarıgül B, Kartum TA, Öndüç GG, Şahin SA, Ramazanoğlu AF. Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures. Med J West Black Sea. 2026;10(1):157-163. doi:10.29058/mjwbs.1793536
Chicago
Aydın, Levent, Buse Sarıgül, Tufan Agah Kartum, Gonca Gül Öndüç, Saime Ayça Şahin, ve Ali Fatih Ramazanoğlu. 2026. “Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures”. Medical Journal of Western Black Sea 10 (1): 157-63. https://doi.org/10.29058/mjwbs.1793536.
EndNote
Aydın L, Sarıgül B, Kartum TA, Öndüç GG, Şahin SA, Ramazanoğlu AF (01 Nisan 2026) Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures. Medical Journal of Western Black Sea 10 1 157–163.
IEEE
[1]L. Aydın, B. Sarıgül, T. A. Kartum, G. G. Öndüç, S. A. Şahin, ve A. F. Ramazanoğlu, “Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures”, Med J West Black Sea, c. 10, sy 1, ss. 157–163, Nis. 2026, doi: 10.29058/mjwbs.1793536.
ISNAD
Aydın, Levent - Sarıgül, Buse - Kartum, Tufan Agah - Öndüç, Gonca Gül - Şahin, Saime Ayça - Ramazanoğlu, Ali Fatih. “Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures”. Medical Journal of Western Black Sea 10/1 (01 Nisan 2026): 157-163. https://doi.org/10.29058/mjwbs.1793536.
JAMA
1.Aydın L, Sarıgül B, Kartum TA, Öndüç GG, Şahin SA, Ramazanoğlu AF. Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures. Med J West Black Sea. 2026;10:157–163.
MLA
Aydın, Levent, vd. “Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures”. Medical Journal of Western Black Sea, c. 10, sy 1, Nisan 2026, ss. 157-63, doi:10.29058/mjwbs.1793536.
Vancouver
1.Levent Aydın, Buse Sarıgül, Tufan Agah Kartum, Gonca Gül Öndüç, Saime Ayça Şahin, Ali Fatih Ramazanoğlu. Clinical and radiological outcome comparison of unilateral vs. bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures. Med J West Black Sea. 01 Nisan 2026;10(1):157-63. doi:10.29058/mjwbs.1793536

Batı Karadeniz Tıp Dergisi, Zonguldak Bülent Ecevit Üniversitesi tarafından yayımlanan, uluslararası, hakemli ve açık erişimli bir dergidir. İlk sayısı 2017 yılında yayımlanan dergi, yılda üç kez (Nisan, Ağustos ve Aralık aylarında) yayımlanmakta olup Türkçe ve İngilizce makalelere yer verir.