A retrospective study of molar pregnancy cases submitted to our clinic: 5 years clinical experience

Abstract

Aim: In this study, we aimed to determine the incidence of gestational trophoblastic disease by using data of patients who were treated for molar pregnancies. Material and methods: . The patients diagnosed as gestational trophoblastic disease between January 2009- January 2014 was evaluated retrospectively. Patients’ age, gravidity, parity and aborts were noted. Patients’ history, ultrasonographic findings, β HCG and laboratory results, hystopathology findings, treatment modalities and β HCG for following-up were recorded. Results: The incidence of molar pregnancy was found as 8 per 1000 deliveries. The mean age of patients was 28.72 ±7,5 and mean gestastional week was 10±2,4. β HCG values was found between 240 and 145100. Out of all patients, 20 (33.3%) had ultrasonographic signs of molar pregnancy. Pathology results revealed partial mole in 45 (75%), complete mole in 12 (20%) patients and choriocarcinoma in 3 (5%) patients. No mortality related to disease and complications was observed

Keywords

• Gestational Trophoblastic Disease
• incidence
• retrospective

KLİNİĞİMİZE BAŞVURAN MOL GEBELİK OLGULARININ RETROSPEKTİF İNCELENMESİ: 5 YILLIK KLİNİK DENEYİM

Öz

Amaç: Bu çalışmada kliniğimizde molar gebelik
tanısıyla tedavi edilen hastaların verileri
kullanılarak gestasyonel trofoblastik hastalıkların
insidansını belirlemeyi amaçladık.
Gereç ve yöntem: Ocak 2009 ve Ocak 2014 yılları
arasında kliniğimizde molar gebelik tanısı almış
hastaların dosyaları retrospektif olarak incelendi.
Hastaların yaş, gravida, parite ve abortus bilgileri
kaydedildi. Olguların hikayesi, ultrasonografi
bulguları, β HCG ile birlikte laboratuar değerleri,
histopatoloji sonuçları, tedavi yöntemleri ve takipte
β HCG değerleri kayıt edildi.

Bulgular: Kliniğimizdeki molar gebelik insidansı
1000 doğumda 5 olarak bulundu. Hastaların
ortalama yaşı 28.72 ±7,5 olup ortalama gestasyonel
yaş 10±2,4 haftaydı. β HCG değerleri 240 ile
145100 arasında değişmekteydi. Hastaların
20’sinde (%33.3) ultrason bulgusu molar gebelik ile
uyumlu izlenmişti. Patoloji sonuçları 45 (%75)
hastada parsiyel mol, 12 (%20) hastada komplet
mol ve 3 (%5) hastada koryokarsinom gelmiştir.
Olgularda hastalık ve komplikasyonlarına ait ölüm
olgusuna rastlanmamıştır.
Sonuç: Kliniğimizde gestasyonel trofoblastik
hastalık insidansı 1000 doğumda 5 olup daha kesin
bir insidansa ulaşmak için ileri düzeyde araştırmalar
yapılması gerekmektedir.

Anahtar Kelimeler

• Gestasyonel trofoblastik hastalık
• insidans
• MOL

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