KLARİTROMİSİNE BAĞLI GELİŞEN AKUT PANKREATİT

Yıl 2012, Cilt: 3 Sayı: 11, 38 - 42, 03.03.2015

M. Çelik Mehmet Demir Melda Bulgurcu Ali Karakuş Gamze Kavvasoğlu

Öz

Most cases of acute pancreatitis develop due to biliary tract diseases or alcohol intake. Other factors of may lead to acute pancreatitis include abdominal trauma, endoscopic retrograde cholangio pancreatography, hyperparathyroidism, hyperlipideamia, viral infections and drugs. It is estimated that 2% of cases of acute pancreatitis are related to drugs. A 33 year-old male patient who had peptic ulcer was receiving claritromicin, amoxicillin and lansoprazole admitted to the hospital with acute pancreatitis symptoms in the third day of his treatment. Except for the usage of clarithromycin, the patient did not take any other drugs and there was no other obvious cause for his acute pancreatitis. There were a few reports of acute pancreatitis associated
with other macrolide antibiotics in the literature. In this article, we present a case of acute pancreatitis after a course of clarithromycin.

Anahtar Kelimeler

Clarithromycin, acute pancreatitis, macrolid

KLARİTROMİSİNE BAĞLI GELİŞEN AKUT PANKREATİT

Öz

Akut pankreatit vakalarının çoğu safra yolu hastalıkları ve alkol kullanımı nedeniyle gelişir. Akut pankreatite yol açabilecek diğer faktörler abdominal travma, endoskopik retrograd kolanjiyo pankreatografi, hiperparatiroidi, hiperlipidemi, viral enfeksiyonlar ve ilaçları içerir. Akut pankreatitlerin %2’sinin ilaçlarla ilişkili olduğu düşünülmektedir. Otuz üç yaşında erkek hasta peptik ülser nedeniyle kendisine başlanmış olan klaritromisin, amoksisilin ve lansoprazol tedavisinin üçüncü günü kliniğimize pankreatit bulgularıyla başvurdu. Hastada klaritromisin kullanımı dışında pankreatit nedeni olabilecek herhangi bir ilaç kullanımı bulunmamaktaydı. Literatürde makrolid grubu antibiyotik kullanımına bağlı olarak geliştiği bildirilmiş olan birkaç akut pankreatit olgusu mevcuttur. Bu makalede de klaritromisin kullanımı sonrası gelişen akut pankreatitli bir olgu sunulmak istenmiştir.

Anahtar Kelimeler

Klaritromisin, akut pankreatit, makrolid

Kaynakça

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