Öz
Giriş: Ameloblastoma lokal invazyon yapan,
yavaş büyüyen odontojenik epitel orjinli
benign bir tümördür. Sıklıkla mandibula olmak
üzere çene kemiklerine yerleşirler. Folliküler
Ameloblastoma konvansiyonel
ameloblastomların bir subtipidir. Biz de
mandibulada destrüksiyona neden olmuş bir
olgumuzu sunmak istedik.
Olgu: Kırkdokuz yaşında bir erkek hasta ağız
içinde şişlik şikayetiyle Mustafa Kemal
Üniversitesi (MKÜ) Diş Hekimliği Fakültesi
Polikliniğine başvurmuştur. Panoramik
incelemede mandibulada multilobüle tümöral
lezyon izlenmesi üzerine, yapılan bilgisayarlı
tomografi görüntülemesinde sol mandibula
ramus angulus düzeyinde 5.5x4.5 cm
boyutlarında yer yer kistik alanlar içeren
ekspansiyon ve destrüksiyon yapmış kitle
lezyonu tespit edilmiştir. Lezyondan alınan
insizyonel biopsinin MKÜ Tıp Fakültesi
Patoloji laboratuarında ameloblastoma ile
uyumlu raporlanması üzerine MKÜ Tıp
Fakültesi Hastanesi KBB ekibi tarafından
hastanın radikal eksizyonu gerçekleştirilmiştir.
Materyalin incelenmesinde olgunun
ameloblastoma folliküler varyant tanısı
onaylanarak hastanın lokalrekürrens ihtimali
nedeniyle takibi önerilmiştir.
Sonuç: Ameloblastomalar odontojenik epitel
orjinli en sık rastlanılan gerçek neoplazmlardır.
Ameloblastomalarda tedavi lezyonun
natüründen çok yayılımına ve çevre yapılarla
ilişkisine bağlıdır.
Anahtar Kelimeler
Kaynakça
- Ledesma-Montes C, Mosqueda-Taylor A, Carlos-Bregni R, León ER, Palma-Guzmán JM,
- Paéz-Valencia C, Meneses-García A. Ameloblastomas: a regional Latin-America multicentric
- study. Oral Diseases.2007;13.303–7.
- Sun ZJ, Wu YR, Cheng N, Zwahlen RA, Zhao YF. Desmoplastic ameloblastoma - A
- review. Oral Oncology. 2009;45.752–9.
- Hertog D, van der Waal I. Ameloblastoma of the jaws: A critical reappraisal based on a 40-
- years single institution experience. Oral Oncology. 2010;46.61–4.
- Thompson L. World Health Organization classification of tumours: pathology and genetics
- of head and neck tumours. Ear Nose Throat J. 2006;85:74.
- Jun Li T,Tang Wu Y,Feng Yu S,Yan Yu G. Unicystic ameloblastoma. American Journal of
- Surgical Pathology. 2000;24:1385-92.
- Robinson L,Martinez M. Unicystic Ameloblastoma: A prognostically distinct entity.
- Cancer 1977;40.2278-85.
- Curi M M, Dib L L, Pinto DS. Management of solid ameloblastoma of the jaws with liquid
- nitrogenspray cryosurgery. Oral Surgery Oral Medicine, Oral Pathology, Oral Radiology and
- Endodontics. 1997;84.339-44.
- Jones S P,Ghali G E,Lowe B.Eichstaedt M. Large maxillary mass in a child. Journal of
- Oral and Maxillofacial Surgery. 2001;59.1057-61.
- Lau S K, Tideman H,Wu PsC. Ameloblastic carcinoma of the jaws. Oral Surgery Oral
- Medicine, Oral Pathology, Oral Radiology and Endodontics. 1998;85.78-81.
- Ameloblastoma: biological profile of 3677 cases. Reichart PA, Philipsen HP, Sonner S.
- Europian Journal of Cancer Biology and Oral Oncology. 1995;31.86-99.
Öz
Introduction: Ameloblastoma is a benign
epithelial odontogenic tumor which is locally
invasive and of slow growth. Ameloblastomas
locates on jaw bones preferably mandibula.
Follicular ameloblastoma is a subtype of
conventional ameloblastomas. We present our
case that has caused wide destruction in
mandibula.
Case: A-49-year old male patient referred to
Mustafa Kemal University Dentistry
Department with intra-oral sweeling. On
panoramic view, a multilobular tumoral lesion
has been determined and computed
tomography scan revealed 5.5x4.5 cm sized
mass lesion with cystic areas that has
destructed and expanded left mandibula ramus
angulus. Theincisional biopsy has been
reported as ameloblastoma by MKU Pathology
Laboratory and the patient was sent to
Otorhinology Department for radical surgery.
The final diagnosis has been confirmed as
follicular ameloblastoma after the examination
of the material and follow-up of the patient has
been advised for local recurrence.
Conclusion: Ameloblastomas are the most
frequent neoplasms of real
odontogenicepithelium. The prognosis of the
treatment is basically dependent to the
extension of the lesion and adjacent structures
involvement rather than origin of lesion
Anahtar Kelimeler
Kaynakça
- Ledesma-Montes C, Mosqueda-Taylor A, Carlos-Bregni R, León ER, Palma-Guzmán JM,
- Paéz-Valencia C, Meneses-García A. Ameloblastomas: a regional Latin-America multicentric
- study. Oral Diseases.2007;13.303–7.
- Sun ZJ, Wu YR, Cheng N, Zwahlen RA, Zhao YF. Desmoplastic ameloblastoma - A
- review. Oral Oncology. 2009;45.752–9.
- Hertog D, van der Waal I. Ameloblastoma of the jaws: A critical reappraisal based on a 40-
- years single institution experience. Oral Oncology. 2010;46.61–4.
- Thompson L. World Health Organization classification of tumours: pathology and genetics
- of head and neck tumours. Ear Nose Throat J. 2006;85:74.
- Jun Li T,Tang Wu Y,Feng Yu S,Yan Yu G. Unicystic ameloblastoma. American Journal of
- Surgical Pathology. 2000;24:1385-92.
- Robinson L,Martinez M. Unicystic Ameloblastoma: A prognostically distinct entity.
- Cancer 1977;40.2278-85.
- Curi M M, Dib L L, Pinto DS. Management of solid ameloblastoma of the jaws with liquid
- nitrogenspray cryosurgery. Oral Surgery Oral Medicine, Oral Pathology, Oral Radiology and
- Endodontics. 1997;84.339-44.
- Jones S P,Ghali G E,Lowe B.Eichstaedt M. Large maxillary mass in a child. Journal of
- Oral and Maxillofacial Surgery. 2001;59.1057-61.
- Lau S K, Tideman H,Wu PsC. Ameloblastic carcinoma of the jaws. Oral Surgery Oral
- Medicine, Oral Pathology, Oral Radiology and Endodontics. 1998;85.78-81.
- Ameloblastoma: biological profile of 3677 cases. Reichart PA, Philipsen HP, Sonner S.
- Europian Journal of Cancer Biology and Oral Oncology. 1995;31.86-99.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Case Report |
| Yazarlar | |
| Yayımlanma Tarihi | 3 Mart 2015 |
| Gönderilme Tarihi | 1 Mart 2015 |
| Yayımlandığı Sayı | Yıl 2012 Cilt: 3 Sayı: 12 |
