Unusual suspects of secondary diabetes and growth retardation: Bartter and Gitelman syndrome

Abstract

Bartter syndrome  and Gitelman syndrome  are rare autosomal recessive syndromes. In extremely rare cases, GS may diagnosed with growth retardation and diabetes mellitus. In this 3-case series, growth retardation was identified at 17-year follow-up of our dizygotic twin patients diagnosed with BS and glucose metabolism disorder was developed.  Whereas, 3^RD. patient diagnosed with GS in adulthood period developed diabetes mellitus after 8 years follow up. Chronic hypopotassemia has been shown to cause diabetes mellitus and growth retardation ın several articles. Potassium plays an important role in insulin, IGF-1 and growth hormone cycle. Herein, we aimed to draw attention to that, the presence of chronic hypopotassemia may precipitate to diseases such as growth retardation and diabetes mellitus over time.

Keywords

• Diabetes Mellitus,Bartter syndrome,Gitelman syndrome

Kaynakça

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