DNA Protective Assay and Some Biochemical Properties of Galium Species

Yıl 2024, Cilt: 12 Sayı: 1, 24 - 30, 01.07.2024

Yener Tekeli , Ömer Kılıç , Elif Esra Altuner

https://doi.org/10.18586/msufbd.1451599

Öz

Herbal-derived drugs prepared using various extracts obtained from different organs of plants that have been scientifically proven to be “medicinal” or directly from these plants are often used today as a method to prevent or treat diseases in humans and animals. This method, called phytotherapy, is a rational, evidence-based, and allopathic treatment method and deals with which active substance group is responsible for the biological effects. In this context, the phytotherapeutic effectiveness of Galium species, which are also used for medicinal purposes among the public, has been examined and proven in many studies. In this study, the biochemical efficacies of five different Galium species were measured and their antioxidant, antimicrobial, and DNA protective effects were tested. It was found that the tested Galium species showed remarkable biochemical efficacies. The results were also compared with the results of some other studies in the literature.

Anahtar Kelimeler

Antimicrobial, Antioxidant, DNA, Phytotherapy, Protective assay

DNA Koruyucu Testi ve Galium Türlerinin Bazı Biyokimyasal Özellikleri

Öz

Bilimsel olarak “tıbbi” olduğu kanıtlanmış bitkilerin farklı organlarından elde edilen çeşitli ekstraktlar veya doğrudan bu bitkilerden elde edilen çeşitli ekstraktlar kullanılarak hazırlanan bitkisel kökenli ilaçlar, günümüzde insanlarda ve hayvanlarda hastalıkların önlenmesi veya tedavisinde bir yöntem olarak sıklıkla kullanılmaktadır. Fitoterapi adı verilen bu yöntem akılcı, kanıta dayalı, allopatik bir tedavi yöntemi olup, biyolojik etkilerden hangi etken madde grubunun sorumlu olduğunu ele almaktadır. Bu bağlamda halk arasında tıbbi amaçlı da kullanılan Galium türlerinin fitoterapötik etkinliği birçok çalışmada incelenmiş ve kanıtlanmıştır. Bu çalışmada beş farklı Galium türünün biyokimyasal etkinlikleri ölçülmüş, antioksidan, antimikrobiyal ve DNA koruyucu etkileri test edilmiştir. Test edilen Galium türlerinin dikkate değer biyokimyasal etkinlik gösterdiği tespit edildi. Sonuçlar ayrıca literatürdeki diğer bazı çalışmaların sonuçlarıyla da karşılaştırıldı.

Anahtar Kelimeler

Antimikrobiyal, Antioksidan, DNA, Galium türleri, Fitoterapi, Koruyucu tahlil

Kaynakça

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