Alıç (Crataegus): Sağlık İçin Doğanın Küçük Mucizesi!

Öz

Alıç bitkisinden elde edilen meyve, yapraklar ve çiçekler, içerdiği biyoaktif bileşenlerinin sağlık üzerine olumlu etkileri sayesinde geleneksel tıp uygulamalarında yüzyıllardır kullanılmaktadır. Alıç; Asya, Avrupa, Afrika ve Amerika’da yetişebilen, tür çeşitliliği açısından zengin bir bitkidir. Alıcın türü ve yetiştiği coğrafi bölge, kimyasal bileşiminde etkili olmaktadır. Bu bitkinin meyve, yaprak ve çiçek kısmından elde edilen ekstraktlar çeşitli biyoaktif bileşenler içermektedir. Alıç bitkisinden 300’den fazla kimyasal bileşen izole edilmiştir. Bitkinin temel kimyasal bileşenleri flavonoidler ve organik asitlerdir. İçeriğinde bulunan bu biyoaktif bileşenlerin, hastalıklardan korunmada ve tedavide faydalı olabileceği düşünülmektedir. Dünyadaki ölüm nedenlerinin başında gelen kardiyovasküler hastalıkların tedavisinde ve önlenmesinde alıç ekstraktının yararlı etkileri gösterilmiştir. Yapılan çalışmalarda, alıç ekstraktının GLUT4 ekspresyonu ile hücreye glukoz girişini arttırdığı belirtilmiştir. Dolayısıyla Diabetes mellitus (DM)’ün tedavisinde ve komplikasyonlarının azaltılmasında kullanılabileceği öne sürülmüştür. Yapılan in-vitro ve in-vivo çalışmalarda alıcın; anti-oksidan, anti-mikrobiyal, anti-hipertansif, anti-kanserojenik vb. etkileri gösterilmiştir. Alıç tüketiminin, ilaçların etkisini güçlendirebileceği ya da engelleyebileceği göz önünde bulundurularak, ilaç kullanan kişilerin, alıcı hekim kontrolünde tüketmesi önerilmektedir. Bu derlemede amaç alıç bitkisinin kimyasal bileşenleri ile potansiyel faydaları hakkında bilgi vermek, terapötik formülasyonların ve gıda uygulamalarının geliştirilmesine katkı sunmaktır.

Anahtar Kelimeler

• Alıç
• Antioksidan
• Fonksiyonel besin
• Sağlık

Howthorn (Crataegus): Nature’s Little Miracle for Health!

Öz

The fruit, leaves and flowers obtained from the hawthorn plant have been used in traditional medicine practices for centuries, thanks to the positive health effects of the bioactive components it contains. Hawthorn; It is a plant rich in species diversity that can grow in Asia, Europe, Africa and America. The type of wheat and the geographical region where it grows affect its chemical composition. Extracts obtained from the fruit, leaves and flowers of this plant contain various bioactive components. More than 300 chemical compounds have been isolated from the hawthorn plant. The main chemical components of the plant are flavonoids and organic acids. It is thought that these bioactive components contained in it may be useful in the prevention and treatment of diseases. The beneficial effects of hawthorn extract have been shown in the treatment and prevention of cardiovascular diseases, which are the leading causes of death in the world. Studies have shown that hawthorn extract increases glucose entry into the cell through GLUT4 expression. Therefore, it has been suggested that it can be used in the treatment of Diabetes mellitus (DM) and reducing its complications. In in-vitro and in-vivo studies, the recipient; anti-oxidant, anti-microbial, anti-hypertensive, anti-carcinogenic, etc. effects have been shown. Considering that hawthorn consumption can strengthen or inhibit illumination, the person using the drug should consume it under the supervision of a physician. The aim of this review is to provide information about the chemical components and potential benefits of hawthorn plant and to contribute to the development of therapeutic formulations and food applications.

Anahtar Kelimeler

• Hawthorn
• Antioxidant
• Functional food
• Health

Kaynakça

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