Evaluation of Knowledge, Attitude and Practices of Nurses Working in a University Hospital About Pharmacovigilance

Yıl 2019, , 285 - 293, 25.09.2019

Nalan Tiftik , İbrahim Duman İsmail Ün

https://doi.org/10.31020/mutftd.581540

Cited By: 1

Öz

Aim:
Although detection and monitoring of adverse drug
reactions is mandatory for drug safety, the reporting of adverse drug reactions
are insufficient in our country. On the other hand, raising awareness of the
importance of pharmacovigilance among nurses is important for reporting adverse
drug reactions. The main purpose of this study is to evaluate the knowledge,
attitudes and practices about pharmacovigilance of nurses working in a
university hospital.

Methods:
In this cross-sectional and descriptive study, a
25-question questionnaire was applied to evaluate their knowledge, attitudes
and practices on pharmacovigilance to nurses working in Mersin University
Hospital.

Results:
83.9% of the nurses defined the pharmacovigilance
correctly and 40.7% knew that there was a pharmacovigilance contact point in
the hospital. 81.7% of nurses are aware that reporting adverse drug reactions
is a professional obligation. While 48.8% of the nurses reported that they had
experienced an adverse drug reaction but only 0.2% of them had reported an
adverse drug reaction. 75.1% of the nurses reported that it was difficult to
decide on an adverse drug reaction
and 36.6% of the nurses showed that there was not enough time to report an
adverse drug reaction.

Conclusions:
In this study, it was observed that nurses
participating in the study had deficiencies in knowledge, attitude and
practices related to pharmacovigilance. The rate of adverse drug reaction
reporting among nurses is very low. Pharmacovigilance training should be
organized for nurses in hospitals and nurses should be involved in this
process. In this way, it could be ensured that nurses make the necessary
contribution to the reporting of adverse drug reactions.

Anahtar Kelimeler

Adverse drug reaction, pharmacovigilance, nurse

Bir Üniversite Hastanesinde Görev Yapan Hemşirelerin Farmakovijilans Hakkında Bilgi, Tutum ve Uygulamalarının Değerlendirmesi

Öz

Amaç: Advers ilaç reaksiyonlarının tespit edilmesi ve izlenmesi ilaç
güvenliği açısından zorunlu olmasına rağmen, ülkemizde advers ilaç reaksiyonu
bildirimi yetersizdir. Öte yandan hemşirelerde farmakovijilansın önemi hakkında
farkındalık yaratmak advers ilaç reaksiyonu bildirimi için önem arz etmektedir.
Bu çalışmanın temel amacı bir üniversite hastanesinde çalışan hemşirelerin
farmakovijilans konusundaki bilgi, tutum ve uygulamalarını değerlendirmektir.

Yöntem: Kesitsel ve tanımlayıcı tipte yapılan bu çalışmada, Mersin
Üniversitesi Hastanesinde çalışan hemşirelerin farmakovijilans konusunda bilgi,
tutum ve uygulamalarını değerlendirmek için 25 soruluk anket uygulanmıştır.

Bulgular: Hemşirelerin %83,9’u farmakovijilansı doğru tanımlamış ve %40,7’si
hastanede bir farmakovijilans irtibat noktasının olduğunu bilmiştir.
Hemşirelerin %81,7’si advers ilaç reaksiyonu bildiriminin profesyonel bir
yükümlülük olduğunun farkındadır. Hemşirelerin %48,8’i yaşanan bir advers ilaç
reaksiyonu gördüğünü bildirmekle birlikte sadece %0,2’si advers ilaç reaksiyonu
bildirimi yaptığını ifade etmiştir. Yaşanan bir advers ilaç reaksiyonunu
tanımlamada hemşirelerin %75,1’i karar vermenin zor olduğunu bildirmiş ve
advers ilaç reaksiyonunu bildirmek için hemşirelerin %36,6’sı yeterli
zamanlarının olmadığını sebep olarak göstermişlerdir.

Sonuç: Bu çalışmada araştırmaya katılan hemşirelerin farmakovijilans ile
ilgili bilgi, tutum ve uygulamalarında eksiklikleri olduğu görülmüştür.
Hemşireler arasında advers ilaç reaksiyonu bildirimi oranı çok düşüktür.
Hastanelerde hemşireler için farmakovijilans ile ilgili eğitimler düzenlenmeli
ve hemşirelerin bu süreçte yer almaları sağlanmalıdır. Bu şekilde advers ilaç
reaksiyonlarının bidiriminde hemşirelerin gerekli katkıyı sunması sağlanabilir.

Anahtar Kelimeler

Advers ilaç reaksiyonu, farmakovijilans, hemşire

Kaynakça

• World Health Organization (2002) Safety of medicines: A guide to detecting and reporting adverse drug reactions:why health professionals need to take action. Geneva: World Health Organization; 2002.
• Campbell JE, Gossell-Williams M, Lee MG. A Review of Pharmacovigilance. West Indian Med J 2014; 63 (7): 771.
• Lindquist M, Edwards IR. The WHO Programme for International Drug Monitoring, its database, and the technical support of the Uppsala Monitoring Center. J Rheumatol 2001;28:1180-7.
• Ithnin M, et al. Mobile App Design, Development, and Publication for Adverse Drug Reaction Assessments of Causality, Severity, and Preventability. JMIR Mhealth Uhealth 2017;5(5):e78.
• Ergün Y, et al. Knowledge attitude and practice of Turkish health professionals towards pharmacovigilance in a university hospital. Int Health. 2019 May 1;11(3):177-184.
• Bhagavathula AS, at al. Health Professionals' Knowledge, Attitudes and Practices about Pharmacovigilance in India: A Systematic Review and Meta-Analysis. PLoS One. 2016 Mar 24;11(3):e0152221.
• Ozcan G, et al. Adverse drug reaction reporting pattern in Turkey: analysis of the national database in the context of the first pharmacovigilance legislation. Drugs Real World Outcomes 2016;3:33–43.
• Toklu HZ, Uysal MK. The knowledge and attitude of the Turkish community pharmacists toward pharmacovigilance in the Kadikoy district of Istanbul. Pharm World Sci (2008) 30:556–562.
• Taylan S, Alan S, Kadıoğlu S. Hemşirelik Rolleri ve Özerklik. Hemşirelikte Araştırma Geliştirme Dergisi 2012 -2.
• Alan S, et al. An evaluation of knowledge of pharmacovigilance among nurses and midwives in Turkey. Indian J Pharmacol 2013;45:616–18.
• Conforti A, et al. Adverse drug reaction reporting by nurses: analysis of Italian pharmacovigilance database. Pharmacoepidemiology and drug safety 2012; 21: 597–602.
• Ranganathan SS, et al. The involvement of nurses in reporting suspected adverse drug reactions: experience with the meningococcal vaccination scheme. Br J Clin Pharmacol 2003; 56: 658–63.
• Ulfvarson J, Mejyr S, Bergman U. Nurses are increasingly involved in pharmacovigilancein Sweden. Pharmacoepidemiol Drug Saf 2007; 16: 532–7.
• Hall M, et al. The spontaneous reporting of adverse drug reactions by nurses. Br J Clin Pharmacol 1995; 40: 173–5
• Opri S, et al. Venus study: a research and education project on nurses and drug surveillance. Assist Inferm Ric 2011; 30: 6–15.
• Vural F, Çiftçi S, Vural B. The knowledge, attitude and behaviours of nurses about pharmacovigilance, adverse drug reaction and adverse event reporting in a state hospital. North Clin İstanb 2014;1:147–52.
• Toklu HZ, et al. The knowledge and attitude of the healthcare professionals towards pharmacovigilance and adverse drug reaction reporting in northern Cyprus. J Pharmacovigil 2016;4:1–7.
• Şavlı E, Şavlı E. The Importance of Pharmacovigilance and Ecopharmacovigilance in Nursing Education. Ordu University Journal of Nursing Studies 2019;2(1),70-8.
• Vural F, Çiftçi S, Vural B. Sık karşılan ilaç uygulama hataları ve ilaç güvenliği. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2014;5(4):271-5.
• Uzuntarla Y, Cihangiroğlu N. The analysis of relationship between nurses’ rational use of drugs and their personal characteristic. TAF Preventive Medicine Bulletin; 2016, Cilt 15, sayı 1. DOI: 10.5455/pmb.1-1428420168.
• Kaya D, Sürmelioğlu N, Karataş Y. Past, Present and Future of Pharmacovigilance. Archives Medical Review Journal, 2016;25 (1):129-39.