Removal of amoxicillin in aqueous media by hybrid adsorption/oxidation

Abstract

The most consumed penicillin group, an antibiotic active ingredient in Europe and Turkey, is Amoxicillin (AMX). Due to its lipophilic structure and low biodegradability, it is discharged into the receiving environment from conventional wastewater treatment plants without treatment. It is detected at the micro and nano concentration in receiving environments. But it is thought that their presence will increase in environment parallel to their increasing use. It is essential to prevent the contamination of natural water resources with antibiotic drug active ingredients for Turkey, a country with the 6th highest global antibiotic resistance. In this study, it was aimed to remove AMX from the aquatic media with the synthesized a new adsorbent (Fe3O4&Tween-85@PEI and HOCI) and a strong oxidant hypochlorous acid (HOCI). While AMX was removed 25% by adsorption at room temperature in 30 minutes at pH: 2, was degraded 80% by HOCI at the same pH and 500C with 0.025 mM concentration. According to obtained results, the adsorption process is physical, and the advanced oxidation is chemical. The adsorption and the oxidation processes were fitted to the Freundlich isotherm and the pseudo-second order kinetic respectively.

Keywords

• Amoxicillin
• Adsorption
• Oxidation

Sucul ortamdan amoksisilin gideriminde hibrit adsorpsiyon/oksidasyon performansının değerlendirilmesi

Öz

Avrupa ve Türkiye genelinde en çok tüketilen penisilin grubu antibiyotik ilaç etken maddesi, Amoksisilin (AMX) dir. Lipofilik yapısı ve biyobozunurluğunun çok düşük olması sebebiyle AMX konvansiyonel atıksu arıtma tesislerinde arıtılamadan alıcı ortama verilmektedir. Alıcı ortamlarda mikro ve nano konsantrasyonlarda tespit edilmektedir. Ancak kullanım miktarlarına paralel olarak çevresel ortamlardaki varlıklarının artacağı düşünül mektedir. Küresel antibiyotik direnci en yüksek 6. ülke olan Türkiye için, doğal su kaynaklarının antibiyotik türü etken madde kirliliğine karşın kaynakta engellenmesi oldukça önemlidir. Bu çalışmada, AMX’in, sentezlenen yeni bir adsorban (Fe3O4&Tween-85@PEI) ve kuvvetli bir oksidant hipokloröz asit (HOCI), ile sucul ortamdan giderilmesi amaçlanmıştır. AMX adsorpsiyon ile oda sıcaklığında 30 dakikada pH: 2’de %25 giderilirken, HOCI ile 50 0C’de 0.025 mM konsantrasyonda, aynı pH’da %80 oranında giderilmiştir. Elde edilen sonuçlara göre, adsorpsiyon prosesi fiziksel, oksidasyon işlemi ise kimyasaldır. Adsorpsiyon ve oksidasyon prosesleri sırasıyla Freundlich izotermine ve ikinci derece kinetiğe uyum göstermiştir.

Anahtar Kelimeler

• Amoksisilin
• Adsorpsiyon
• İleri Oksidasyon

Kaynakça

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