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ACUTE FACIAL PARALYSIS DUE TO EBV INFECTION

Yıl 2020, Cilt 8, Sayı 1, 79 - 83, 20.04.2020
https://doi.org/10.37696/nkmj.569544

Öz

Ebstein Barr virus (EBV) is a member of Herpes-viridae. Altough elevations of liver enzymes and upper respiratory tract infection findings is commonly seen during the EBV infection, acute facial paralysis is rare complication. Here, we report acute facial paralysis associated with EBV infection in an eight years old girl. With symptomatic treatment, the patient recovered without cure with corticosteroids and antiviral therapy and no complications developed. Physicians should keep in mind that neurological complications, such as facial paralysis, other than upper respiratory tract infections, may develop during infectious mononucleosis due to EBV and that patients should be followed closely.

Kaynakça

  • Gershon AA, Hotez PJ, Katz SL. Epstein-Barr virus infections. Krugman's infectious diseases of children. 11th. edit. London: Mosby, 2003: 98-115.
  • Fidan I, Yüksel S, İmir T. Değişik yaş gruplarında Epstein-Barr virus antikorlarının araştırılması. J Infect 2005; 19: 453-456.
  • Vouloumanou EK, Rafailidis PI, Falagas ME. Current diagnosis and management of infectious mononucleosis. Curr opin Hematol 2012; 19: 14-20
  • Coddington CT, Isaacs JD, Siddiqui AQ, Andrews TC. Neurological picture. Bilateral facial nerve palsy associated with Epstein-Barr virus infection. JNeurol Neurosurg Psychiatr. 2010; 81: 1155–1156.
  • Diedler J, Rieger S, Koch A, Parthe-Peterhans S, Schwaninger M. Bilateral facial palsy: Epstein-Barr virus, not Lyme disease. Eur JNeurol. 2006; 13: 1029–1030.Ha¨usler M, Ramaekers VT, Doenges M, et al. Neurological complications of acute and persistent Epstein–Barr virus infection in paediatric patients. J Med Virol 2002;68: 253–63.
  • Lennon P, Saunders J, Fenton JE. A longer stay for fort he kissing disease: epidemiology of bacterial tonsillitis and infectious mononucleosis over a 20 year period. J Laryngol Otol 2013; 7: 1-5.
  • González Saldaña N, Monroy Colín VA, Piña Ruiz G, Juárez Olguín H. Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Res Notes. 2012; 6: 361.
  • Medović R, Igrutinović Z, Radojević-Marjanović R, Marković S, Rasković Z, Simović A, Tanasković-Nestorović J, Radovanović M, VuIetić B. Clinical and laboratory differences between Epstein-Barr and cytomegalovirus infectious mononucleosis in children. Srp Arh Celok Lek. 2016; 1-2: 56-62.
  • 10.Chan CW, Chiang AK, Chan KH, Lau AS. Ebstein-Barr virus associated infectious mononucleosis in Chinese children. Pediatr Infect Dis J 2003; 22: 974-978.Sumaya CV, Ench Y. Epstein-Barr virus infectious mononucleosis in children. Pediatrics 1985; 75: 1003-10.
  • Yanagihara N, Hinohira Y, Honda N. Pathogenesis of facial nerve paralysis associated with infectious mononucleosis: rationale based on a review of 2 cases. Facial N Res Jpn 2000; 20:61-63.
  • Stahl N, Ferit T. Recurrent bilateral peripheral facial palsy J Laryngol Otol 1989; 103: 117-119.
  • Terada K, Niizuma T, Kosaka Y, Inoue M, Ogita S, Kataoka N. Bilateral facial nerve palsy associated with Epstein-Barr virus infection with a review of the literature. Scand J Infect Dis. 2004; 36(1): 75-77.
  • De Paschale M, Clerici P. Serological diagnosis of Epstein-Barr virus infection: Problems and solutions. World JVirol. 2012; 1: 31–43.
  • Luderer R, Kok M, Niesters HGM, Schuurman R, deWeerdt O, Thijsen SFT. Real-time Epstein-Barr virus PCR for the diagnosis of primary EBV infections and EBV reactivation.MolDiagn. 2005; 9: 195–200.
  • Yabuki S, Kazahaya Y, Kubonishi I. Epstein-Barr virus antibodies in neurological diseases. FoliaPsychiatrNeurol Jpn. 1985; 39: 85–93.
  • Cengiz AB, Cultu Kantaroğlu O, Secmeer G, Ceyhan M, Kara A, Gurgey A. Infectious mononucleosis in Turkish children. Turk J Pediatr 2010; 52: 245-254.
  • Wilson C, Grant CC. Picture of the month. Facial nevre palsy secondary to Epstein-Barr virus infection. Arch Pediatr Adolesc Med. 1997; 151: 739–740.
  • Grose C, Henle W, Henle G, Feorino PM. Primary Epstein–Barr-Virus Infections in Acute Neurologic Diseases. NEnglJMed. 1975; 292: 392–395.
  • Andersson J, SternerG. A 16-month-old boy with infectious mononucleosis, parotitis and Bell’s palsy. Acta Paediatr Scand. 1985; 74: 629–632.
  • Vogelnik K, Matos A. Facial nerve palsy secondary to Epstein-Barr virus infection of the middle ear in pediatric population may be more common than we think. Wien Klin Wochenschr. 2017; 9: 18.

EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU

Yıl 2020, Cilt 8, Sayı 1, 79 - 83, 20.04.2020
https://doi.org/10.37696/nkmj.569544

Öz

Ebstein Barr virüs (EBV) Herpes-viridae ailesinin bir üyesidir. EBV enfeksiyonu seyrinde üst solunum yolu enfeksiyonu bulguları ile birlikte asemptomatik karaciğer enzimlerinde yükselme sıklıkla izlenmekle birlikte akut fasiyal paralizi oldukça nadir görülmektedir. Burada sekiz yaşında EBV enfeksiyonuna bağlı akut fasiyal paralizi olgusu sunulmuştur. Semptomatik tedavi ile birlikte hasta kortikosteroid ve antiviral tedavi ile sekelsiz iyileşmiş ve herhangi bir komplikasyon gelişmemiştir. Hekimler EBV’ye bağlı gelişen enfeksiyöz mononükleoz seyri sırasında üst solunum yolu enfeksiyonları dışında fasiyal paralizi gibi nörolojik komplikasyonların da gelişebileceğini ve hastaların yakından takip edilmesi gerektiğini akılda bulundurmalıdır.

Kaynakça

  • Gershon AA, Hotez PJ, Katz SL. Epstein-Barr virus infections. Krugman's infectious diseases of children. 11th. edit. London: Mosby, 2003: 98-115.
  • Fidan I, Yüksel S, İmir T. Değişik yaş gruplarında Epstein-Barr virus antikorlarının araştırılması. J Infect 2005; 19: 453-456.
  • Vouloumanou EK, Rafailidis PI, Falagas ME. Current diagnosis and management of infectious mononucleosis. Curr opin Hematol 2012; 19: 14-20
  • Coddington CT, Isaacs JD, Siddiqui AQ, Andrews TC. Neurological picture. Bilateral facial nerve palsy associated with Epstein-Barr virus infection. JNeurol Neurosurg Psychiatr. 2010; 81: 1155–1156.
  • Diedler J, Rieger S, Koch A, Parthe-Peterhans S, Schwaninger M. Bilateral facial palsy: Epstein-Barr virus, not Lyme disease. Eur JNeurol. 2006; 13: 1029–1030.Ha¨usler M, Ramaekers VT, Doenges M, et al. Neurological complications of acute and persistent Epstein–Barr virus infection in paediatric patients. J Med Virol 2002;68: 253–63.
  • Lennon P, Saunders J, Fenton JE. A longer stay for fort he kissing disease: epidemiology of bacterial tonsillitis and infectious mononucleosis over a 20 year period. J Laryngol Otol 2013; 7: 1-5.
  • González Saldaña N, Monroy Colín VA, Piña Ruiz G, Juárez Olguín H. Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Res Notes. 2012; 6: 361.
  • Medović R, Igrutinović Z, Radojević-Marjanović R, Marković S, Rasković Z, Simović A, Tanasković-Nestorović J, Radovanović M, VuIetić B. Clinical and laboratory differences between Epstein-Barr and cytomegalovirus infectious mononucleosis in children. Srp Arh Celok Lek. 2016; 1-2: 56-62.
  • 10.Chan CW, Chiang AK, Chan KH, Lau AS. Ebstein-Barr virus associated infectious mononucleosis in Chinese children. Pediatr Infect Dis J 2003; 22: 974-978.Sumaya CV, Ench Y. Epstein-Barr virus infectious mononucleosis in children. Pediatrics 1985; 75: 1003-10.
  • Yanagihara N, Hinohira Y, Honda N. Pathogenesis of facial nerve paralysis associated with infectious mononucleosis: rationale based on a review of 2 cases. Facial N Res Jpn 2000; 20:61-63.
  • Stahl N, Ferit T. Recurrent bilateral peripheral facial palsy J Laryngol Otol 1989; 103: 117-119.
  • Terada K, Niizuma T, Kosaka Y, Inoue M, Ogita S, Kataoka N. Bilateral facial nerve palsy associated with Epstein-Barr virus infection with a review of the literature. Scand J Infect Dis. 2004; 36(1): 75-77.
  • De Paschale M, Clerici P. Serological diagnosis of Epstein-Barr virus infection: Problems and solutions. World JVirol. 2012; 1: 31–43.
  • Luderer R, Kok M, Niesters HGM, Schuurman R, deWeerdt O, Thijsen SFT. Real-time Epstein-Barr virus PCR for the diagnosis of primary EBV infections and EBV reactivation.MolDiagn. 2005; 9: 195–200.
  • Yabuki S, Kazahaya Y, Kubonishi I. Epstein-Barr virus antibodies in neurological diseases. FoliaPsychiatrNeurol Jpn. 1985; 39: 85–93.
  • Cengiz AB, Cultu Kantaroğlu O, Secmeer G, Ceyhan M, Kara A, Gurgey A. Infectious mononucleosis in Turkish children. Turk J Pediatr 2010; 52: 245-254.
  • Wilson C, Grant CC. Picture of the month. Facial nevre palsy secondary to Epstein-Barr virus infection. Arch Pediatr Adolesc Med. 1997; 151: 739–740.
  • Grose C, Henle W, Henle G, Feorino PM. Primary Epstein–Barr-Virus Infections in Acute Neurologic Diseases. NEnglJMed. 1975; 292: 392–395.
  • Andersson J, SternerG. A 16-month-old boy with infectious mononucleosis, parotitis and Bell’s palsy. Acta Paediatr Scand. 1985; 74: 629–632.
  • Vogelnik K, Matos A. Facial nerve palsy secondary to Epstein-Barr virus infection of the middle ear in pediatric population may be more common than we think. Wien Klin Wochenschr. 2017; 9: 18.

Ayrıntılar

Birincil Dil Türkçe
Konular Tıp
Bölüm Vaka Sunumu
Yazarlar

Hülya BAYKIZ
NAMIK KEMAL ÜNİVERSİTESİ, TIP FAKÜLTESİ
Türkiye


Ayşin NALBANTOĞLU Bu kişi benim (Sorumlu Yazar)
NAMIK KEMAL ÜNİVERSİTESİ, TIP FAKÜLTESİ
0000-0002-5757-4051
Türkiye


Burçin NALBANTOĞLU
NAMIK KEMAL ÜNİVERSİTESİ, TIP FAKÜLTESİ
Türkiye


Nedim SAMANCI Bu kişi benim
NAMIK KEMAL ÜNİVERSİTESİ, TIP FAKÜLTESİ
Türkiye


Şule Güler KAÇMAZ
NAMIK KEMAL ÜNİVERSİTESİ, TIP FAKÜLTESİ
0000-0001-7044-8837
Türkiye

Yayımlanma Tarihi 20 Nisan 2020
Yayınlandığı Sayı Yıl 2020, Cilt 8, Sayı 1

Kaynak Göster

Bibtex @olgu sunumu { nkmj569544, journal = {Namık Kemal Tıp Dergisi}, issn = {}, eissn = {2587-0262}, address = {Namık Kemal Üniversitesi Tıp Fakültesi Dekanlığı, Namık Kemal Mahallesi Kampüs Caddesi No:1 59100-Süleymanpaşa-TEKİRDAĞ}, publisher = {Namık Kemal Üniversitesi}, year = {2020}, volume = {8}, pages = {79 - 83}, doi = {10.37696/nkmj.569544}, title = {EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU}, key = {cite}, author = {Baykız, Hülya and Nalbantoğlu, Ayşin and Nalbantoğlu, Burçin and Samancı, Nedim and Kaçmaz, Şule Güler} }
APA Baykız, H. , Nalbantoğlu, A. , Nalbantoğlu, B. , Samancı, N. & Kaçmaz, Ş. G. (2020). EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU . Namık Kemal Tıp Dergisi , 8 (1) , 79-83 . DOI: 10.37696/nkmj.569544
MLA Baykız, H. , Nalbantoğlu, A. , Nalbantoğlu, B. , Samancı, N. , Kaçmaz, Ş. G. "EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU" . Namık Kemal Tıp Dergisi 8 (2020 ): 79-83 <https://dergipark.org.tr/tr/pub/nkmj/issue/53521/569544>
Chicago Baykız, H. , Nalbantoğlu, A. , Nalbantoğlu, B. , Samancı, N. , Kaçmaz, Ş. G. "EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU". Namık Kemal Tıp Dergisi 8 (2020 ): 79-83
RIS TY - JOUR T1 - EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU AU - Hülya Baykız , Ayşin Nalbantoğlu , Burçin Nalbantoğlu , Nedim Samancı , Şule Güler Kaçmaz Y1 - 2020 PY - 2020 N1 - doi: 10.37696/nkmj.569544 DO - 10.37696/nkmj.569544 T2 - Namık Kemal Tıp Dergisi JF - Journal JO - JOR SP - 79 EP - 83 VL - 8 IS - 1 SN - -2587-0262 M3 - doi: 10.37696/nkmj.569544 UR - https://doi.org/10.37696/nkmj.569544 Y2 - 2020 ER -
EndNote %0 Namık Kemal Tıp Dergisi EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU %A Hülya Baykız , Ayşin Nalbantoğlu , Burçin Nalbantoğlu , Nedim Samancı , Şule Güler Kaçmaz %T EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU %D 2020 %J Namık Kemal Tıp Dergisi %P -2587-0262 %V 8 %N 1 %R doi: 10.37696/nkmj.569544 %U 10.37696/nkmj.569544
ISNAD Baykız, Hülya , Nalbantoğlu, Ayşin , Nalbantoğlu, Burçin , Samancı, Nedim , Kaçmaz, Şule Güler . "EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU". Namık Kemal Tıp Dergisi 8 / 1 (Nisan 2020): 79-83 . https://doi.org/10.37696/nkmj.569544
AMA Baykız H. , Nalbantoğlu A. , Nalbantoğlu B. , Samancı N. , Kaçmaz Ş. G. EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU. NKMJ. 2020; 8(1): 79-83.
Vancouver Baykız H. , Nalbantoğlu A. , Nalbantoğlu B. , Samancı N. , Kaçmaz Ş. G. EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU. Namık Kemal Tıp Dergisi. 2020; 8(1): 79-83.
IEEE H. Baykız , A. Nalbantoğlu , B. Nalbantoğlu , N. Samancı ve Ş. G. Kaçmaz , "EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU", Namık Kemal Tıp Dergisi, c. 8, sayı. 1, ss. 79-83, Nis. 2020, doi:10.37696/nkmj.569544