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Atık Yakma Fırını Çalışanlarında Gözlemlenen Toksik Metallerin Biyoizlenmesi

Yıl 2021, Cilt: 4 Sayı: 2, 65 - 78, 31.08.2021
https://doi.org/10.38213/ohsacademy.977889

Öz

Atıkların bertarafı ve arıtılması sırasında açığa çıkan kimyasallara maruz kalma, giderek artan bir şekilde potansiyel iş sağlığı sorunu olarak kabul edilmektedir. Atık yakma fırını çeşitli toksik maddeleri yayması ve yakma fırını çalışanların bunlara maruz kalmaları nedeniyle çalışanların sağlığı için tehlike arz etmektedir. Bu nedenle maruziyet seviyeleri dikkatlice ölçülmelidir. Bu durumlarda biyolojik izleme, personellerin gerçek mesleki maruziyetinin tanımlanması ve ilgili sağlık etkilerinin önlenmesi için temel bir tamamlayıcı araç olabilir. Çalışanlarda, çok düşük maruziyet seviyelerinde, sağlık riski değerlendirmesi için hassas ve spesifik biyolojik belirteçlerin geliştirilmesi ve kullanılması konusunda artan bir ilgi vardır. Metale maruz kalan personellerin biyo-izlenmesi üzerine literatürde çok sayıda makale bulunmasına rağmen, atık arıtma faaliyetlerinde kullanılan makalelerde sonuçlar bazen tutarsızdır. Sonuçlar, atık yakma tesislerinin personellerinde ölçülen metal seviyelerinin, Kadmiyum ve Kurşun için bazı önemli istisnalar dışında, genellikle düşük olduğunu göstermektedir. Gelecekteki çalışmalar hem biyolojik hem de çevresel izlemeyi kullanan bir yaklaşıma odaklanması önem arz etmektedir. Metal içeren tozların farklı granülometrik fraksiyonlarının, yani solunabilir, torasik, solunabilir ve ultra ince fraksiyonların ölçümüne özel bir vurgu yapılmalıdır. Ayrıca, iş görevlerinin ve mesleki olmayan maruziyetin özellikleri ve seviyelerinin doğru bir açıklaması her zaman gereklidir.

Destekleyen Kurum

Çanakkale Onsekiz Mart Üniversitesi Bilimsel Araştırmalar Proje Birimi

Proje Numarası

FYL-2020-3180

Kaynakça

  • Agramunt, MC., Domingo, A., Domingo, JL., & Corbella, J., (2003), “Monitoring internal exposure to metals and organ-ic substances in workers at a hazardous waste incinerator after 3 years of operation”, Toxicology Letters, 146(1), 83-91.
  • Akerstrom, M., Barregard, L., Lundh, T., & Sallsten, G., (2012), “Variability of urinary cadmium excretion in spot urine samples, first morning voids, and 24 h urine in a healthy non-smoking population: implications for study design”, Journal of Exposure Science & Environmental Epidemiology, 24(2), 171-179.
  • Bresnitz, EA., Roseman, J., Becker, D., & Gracely, E., (1992), “Morbidity among municipal waste incinerator workers”, American Journal of Industrial Medicine, 22(3), 363-378. Chao, CL., & Hwang, KC., (2005), “Arsenic burden survey among refuse incinerator workers”, Journal of Postgraduate Medicine, 51(2), 98-103.
  • Chen, Y., Graziano, JH., Liu, M., Slavkovich, V., Kalra, T., Argos, M., Islam, T., Ahmed, A., Rakibuz-Zaman, M., Ha-san, R., Sarwar, G., Levy, D., Van Geen, A., & Ahsan, H., (2011), “Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort study”, BMJ, 342, 1 – 11.
  • Chung, CJ., Huang, YL., Huang, YK., Wu, MM., Chen, SY., Hsueh, YM., Chen, CJ., (2013), “Urinary arsenic profiles, and the risks of cancer mortality: a population-based 20-year follow-up study in arseniasis-endemic areas in Taiwan”, Environmental Research, 122, 25 – 30.
  • Domingo, JL., Schuhmacher, M., Agramunt, MC., Muller, L., & Neugebauer, F., (2001), “Levels of metals and organic substances in blood and urine of workers at a new hazardous waste incinerator”, International Archives Occupational and Environmental Health, 74(4), 263-269.
  • Fletcher, AM., & Gelberg, KH.. (2013), “An analysis of mercury exposures among the adult population in New York State”, Journal of Community Health, 38(3), 529 – 537. Fowler, BA., Chou, HSJ., Jones, RL., Sullivan, Jr DW., and Chen, CJ., (2015), Arsenic, Nordberg, GF., Fowler, BA., Nordberg, M., (edt.), Handbook on the Toxicology of Metals, (581-624), Europe, Academic Press.
  • Fujimori, E., Iwata, S., Minamoto, K., Lee, K., Itoh, A., Chiba, K., & Haraguchi, H., (2004), “Partitionings and kinetic behaviors of major-to-ultratrace elements between industrial waste incineration fly and bottom ashes as studied by ICP-AES and ICP-MS”, Analytical Sciences, 20(1), 189-194.
  • Gonzalez, CA., Kogevinas, M., Gadea, E., Huici, A., Bosch, A., Bleda, MJ., & Päpke, O., (2000), “Biomonitoring study of people living near or working at a municipal solid-waste incinerator before and after two years of operation”, Archives of Environmental Health, 55(4), 259-267.
  • Hours, M., Anzivino-Viricel, L., Maitre, A., Perdrix, A., Perrodin, Y., Charbotel, B., & Bergeret, A., (2003), “Morbidity among municipal waste incinerator workers: a cross-sectional study”, International Archives Occupational and Environmental Health, 76(6), 467-472.
  • Hrubá, F., Strömberg, U., Černá, M., Chen, C., Harari, F., Harari, R., Horvat, M., Koppová, K., Kos, A., Krsková, A., Krsnik, M., Laamech, J., Li, YF., Löfmark, L., Lundh, T., Lundström, NG., Lyoussi, B., Mazej, D., Osredkar, J., Pawlas, K., Pawlas, N., Prokopowicz, A., Rentschler, G., Spěváčková, V., Spiric, Z., Tratnik, J., & Bergdahl, IA., (2012), “Blood cadmium, mercury, and lead in children: an international comparison of cities in six European countries and China, Ecuador, and Morocco”, Environmental International, 41, 29 – 34.
  • International Agency for Research on Cancer (IARC), (1993), Mercury and mercury compounds, Beryllium, Cadmium, Mercury, and Exposures in the Glass Manufacturing Industry, (239-345), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2006a), IARC Monographs on the Evaluation of Carcinogenic Risks of Humans Inorganic and Organic Lead Compounds. Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2006b), Vanadium pentoxide, Cobalt in Hard Metals and Cobalt Sulfate, Gallium Arsenide, Indium Phosphide and Vanadium Pentoxide, (227-292), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012a), Arsenic and arsenic compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (41-93), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012b), Beryllium and beryllium compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (95-120), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012c), Cadmium and cadmium compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (121-146), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012d), Chromium (IV) compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (147-168), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012e), Nickel and nickel compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (169-218), Lyon, World Health Organization.
  • Järup, L., (2003), “Hazards of heavy metal contamination”, British Medical Bulletin, 68, 167-182.
  • Lello, R., & Nieri, A., (1998), “Urine mutagenicity and hematic lead evaluation of municipal waste incinerator plant workers”, Ig Mod, 109(3), 313-339.
  • Maître, A., Collot-Fertey, D., Anzivino, L., Marques, M., Hours, M., & Stoklov, M., (2003), “Municipal waste incinerators: air and biological monitoring of workers for exposure to particles, metals, and organic compounds”, Occupational and Environmental Medicine, 60(8), 563-569.
  • Malkin, R., Brandt-Rauf, P., Graziano, J., & Parides, M., (1992), “Blood lead levels in incinerator workers”, Environ-mental Research, 59(1), 265-270.
  • Manno, M., Viau, C., Cocker, J., Colosio, C., Lowry, L., Mutti, A., & Nordberg, M., (2010), “Biomonitoring for occupational health risk assessment (BOHRA)”, Toxicology Letters, 192(1), 3-16.
  • Mari, M., Schuhmacher, M., & Domingo, JL., (2009), “Levels of metals and organic substances in workers at a hazardous waste incinerator: a follow-up study”, International Archives Occupational and Environmental Health, 82(4), 519-528.
  • Morf, LS., Gloor, R., Haag, O., Haupt, M., Skutan, S., Di Lorenzo, F., & Böni, D., (2013), “Precious metals and rare earth elements in municipal solid waste –sources and fate in a Swiss incineration plant”, Waste Management, 33(3), 634-644.
  • Nordberg, GF., Nogawa, K., and Nordberg, M., (2015), Cadmium. Nordberg, GF., Fowler, BA., Nordberg, M., (edt.), Handbook on the Toxicology of Metals, (667-716), Europe, Academic Press.
  • Rajor, A., Xaxa, M., Mehta, R., & Kunal, A., (2012), “An overview on characterization, utilization and leachate analysis of biomedical waste incinerator ash”, Journal of Environmental Management, 108, 36-41.
  • Schuhmacher, M., Domingo, JL., Agramunt, MC., Bocio, A., & Muller, L., (2002), “Biological monitoring of metals and organic substances in hazardous-waste incineration workers”, International Archives Occupational and Environmental Health, 75(7), 500-506.
  • Smith, DR., and Nordberg, M., (2015), General Chemistry, Sampling, Analytical Methods, And Speciation, Nordberg, GF., Fowler, BA., Nordberg, M., (edt.), Handbook on the Toxicology of Metals, (15-44), Europe, Academic Press.
  • Sommar, JN., Svensson, MK., Björ, BM., Elmståhl, SI., Hallmans, G., Lundh, T., Schön, SM., Skerfving, S., & Bergdahl, IA., (2013), “End-stage renal disease and low level exposure to lead, cadmium and mercury; a population-based, pro-spective nested case-referent study in Sweden”, Environmental Health, 12(9), 1 – 10.
  • Tellez-Plaza, M., Navas-Acien, A., Menke, A., & Crainiceanu, CM., (2012), “Cadmium exposure and all-cause and cardiovascular mortality in the U.S. general population”, Environmental Health Perspectives, 120(7), 1017-1022.
  • Valerio, F., (2008), “Review on environmental impact of solid wastes produced by municipal urban waste incinerators”, Epidemiologia e Prevenzione, 32(4-5), 244-253.
  • Wrbitzky, R., Goen, T., Letzel, S., Frank, F., & Angerer, J., (1995), “Internal exposure of waste incineration workers to organic and inorganic substances”, International Archives Occupational and Environmental Health, 68(1), 13-21.
  • Wultsch, G., Misik, M., Nersesyan, A., & Knasmueller, S., (2011), “Genotoxic effects of occupational exposure measured in lymphocytes of waste-incinerator workers”, Mutation Research-Genetic Toxicology Environmental Mutagene-sis, 720, 3-7.
  • Zhao, L., Zhang, F., Wang, K., & Zhu, J., (2008), “Chemical properties of heavy metals in typical hospital waste incinerator ashes in China”, Waste Management, 29, 1114-1121.

Biomonitoring of Toxic Metals Observed in Incinerator Workers

Yıl 2021, Cilt: 4 Sayı: 2, 65 - 78, 31.08.2021
https://doi.org/10.38213/ohsacademy.977889

Öz

Abstract − Exposure to chemicals released throughout the disposal and cure of waste is progressively recognized as a potential occupational health problem. An incinerator emits a variety of toxic substances and therefore their exposure can be a concern for the health of the personnel involved. Therefore, exposure levels must be measured carefully. In these cases, biological monitoring can be an essential complementary tool for identifying the actual occupational exposure of staff and preventing related health effects. There is a growing interest among workers in the development and use of sensitive and specific biomarkers for health risk assessment at very low exposure levels. Although there are many articles in the literature on the biomonitoring of metal exposed personnel, the results are sometimes inconsistent in the articles used in waste treatment activities. This is the first systematic review of large studies investigating the levels of different toxic metals measured in the biological matrices of incinerator workers, according to the Preferred Reporting Elements for Systematic Reviews and Meta-Analysis (PRISMA) methodology. The outcomes indicate that metal levels measured in the staff of waste incinerators are usually low, with some remarkable exceptions for Cd and Pb. Subsequent studies must center on an approach that uses both biological and environmental monitoring. Special importance must be placed on the measurement of varied granulometric fractions of metal- including powders, namely respirable, thoracic, respirable and ultrafine fractions. In addition, an accurate definition of the characteristics and levels of work assignments and non-occupational exposure must all the time be ensured.

Proje Numarası

FYL-2020-3180

Kaynakça

  • Agramunt, MC., Domingo, A., Domingo, JL., & Corbella, J., (2003), “Monitoring internal exposure to metals and organ-ic substances in workers at a hazardous waste incinerator after 3 years of operation”, Toxicology Letters, 146(1), 83-91.
  • Akerstrom, M., Barregard, L., Lundh, T., & Sallsten, G., (2012), “Variability of urinary cadmium excretion in spot urine samples, first morning voids, and 24 h urine in a healthy non-smoking population: implications for study design”, Journal of Exposure Science & Environmental Epidemiology, 24(2), 171-179.
  • Bresnitz, EA., Roseman, J., Becker, D., & Gracely, E., (1992), “Morbidity among municipal waste incinerator workers”, American Journal of Industrial Medicine, 22(3), 363-378. Chao, CL., & Hwang, KC., (2005), “Arsenic burden survey among refuse incinerator workers”, Journal of Postgraduate Medicine, 51(2), 98-103.
  • Chen, Y., Graziano, JH., Liu, M., Slavkovich, V., Kalra, T., Argos, M., Islam, T., Ahmed, A., Rakibuz-Zaman, M., Ha-san, R., Sarwar, G., Levy, D., Van Geen, A., & Ahsan, H., (2011), “Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort study”, BMJ, 342, 1 – 11.
  • Chung, CJ., Huang, YL., Huang, YK., Wu, MM., Chen, SY., Hsueh, YM., Chen, CJ., (2013), “Urinary arsenic profiles, and the risks of cancer mortality: a population-based 20-year follow-up study in arseniasis-endemic areas in Taiwan”, Environmental Research, 122, 25 – 30.
  • Domingo, JL., Schuhmacher, M., Agramunt, MC., Muller, L., & Neugebauer, F., (2001), “Levels of metals and organic substances in blood and urine of workers at a new hazardous waste incinerator”, International Archives Occupational and Environmental Health, 74(4), 263-269.
  • Fletcher, AM., & Gelberg, KH.. (2013), “An analysis of mercury exposures among the adult population in New York State”, Journal of Community Health, 38(3), 529 – 537. Fowler, BA., Chou, HSJ., Jones, RL., Sullivan, Jr DW., and Chen, CJ., (2015), Arsenic, Nordberg, GF., Fowler, BA., Nordberg, M., (edt.), Handbook on the Toxicology of Metals, (581-624), Europe, Academic Press.
  • Fujimori, E., Iwata, S., Minamoto, K., Lee, K., Itoh, A., Chiba, K., & Haraguchi, H., (2004), “Partitionings and kinetic behaviors of major-to-ultratrace elements between industrial waste incineration fly and bottom ashes as studied by ICP-AES and ICP-MS”, Analytical Sciences, 20(1), 189-194.
  • Gonzalez, CA., Kogevinas, M., Gadea, E., Huici, A., Bosch, A., Bleda, MJ., & Päpke, O., (2000), “Biomonitoring study of people living near or working at a municipal solid-waste incinerator before and after two years of operation”, Archives of Environmental Health, 55(4), 259-267.
  • Hours, M., Anzivino-Viricel, L., Maitre, A., Perdrix, A., Perrodin, Y., Charbotel, B., & Bergeret, A., (2003), “Morbidity among municipal waste incinerator workers: a cross-sectional study”, International Archives Occupational and Environmental Health, 76(6), 467-472.
  • Hrubá, F., Strömberg, U., Černá, M., Chen, C., Harari, F., Harari, R., Horvat, M., Koppová, K., Kos, A., Krsková, A., Krsnik, M., Laamech, J., Li, YF., Löfmark, L., Lundh, T., Lundström, NG., Lyoussi, B., Mazej, D., Osredkar, J., Pawlas, K., Pawlas, N., Prokopowicz, A., Rentschler, G., Spěváčková, V., Spiric, Z., Tratnik, J., & Bergdahl, IA., (2012), “Blood cadmium, mercury, and lead in children: an international comparison of cities in six European countries and China, Ecuador, and Morocco”, Environmental International, 41, 29 – 34.
  • International Agency for Research on Cancer (IARC), (1993), Mercury and mercury compounds, Beryllium, Cadmium, Mercury, and Exposures in the Glass Manufacturing Industry, (239-345), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2006a), IARC Monographs on the Evaluation of Carcinogenic Risks of Humans Inorganic and Organic Lead Compounds. Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2006b), Vanadium pentoxide, Cobalt in Hard Metals and Cobalt Sulfate, Gallium Arsenide, Indium Phosphide and Vanadium Pentoxide, (227-292), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012a), Arsenic and arsenic compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (41-93), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012b), Beryllium and beryllium compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (95-120), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012c), Cadmium and cadmium compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (121-146), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012d), Chromium (IV) compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (147-168), Lyon, World Health Organization.
  • International Agency for Research on Cancer (IARC), (2012e), Nickel and nickel compounds, Arsenic, Metals, Fibres, and Dusts. A Review of Human Carcinogens, (169-218), Lyon, World Health Organization.
  • Järup, L., (2003), “Hazards of heavy metal contamination”, British Medical Bulletin, 68, 167-182.
  • Lello, R., & Nieri, A., (1998), “Urine mutagenicity and hematic lead evaluation of municipal waste incinerator plant workers”, Ig Mod, 109(3), 313-339.
  • Maître, A., Collot-Fertey, D., Anzivino, L., Marques, M., Hours, M., & Stoklov, M., (2003), “Municipal waste incinerators: air and biological monitoring of workers for exposure to particles, metals, and organic compounds”, Occupational and Environmental Medicine, 60(8), 563-569.
  • Malkin, R., Brandt-Rauf, P., Graziano, J., & Parides, M., (1992), “Blood lead levels in incinerator workers”, Environ-mental Research, 59(1), 265-270.
  • Manno, M., Viau, C., Cocker, J., Colosio, C., Lowry, L., Mutti, A., & Nordberg, M., (2010), “Biomonitoring for occupational health risk assessment (BOHRA)”, Toxicology Letters, 192(1), 3-16.
  • Mari, M., Schuhmacher, M., & Domingo, JL., (2009), “Levels of metals and organic substances in workers at a hazardous waste incinerator: a follow-up study”, International Archives Occupational and Environmental Health, 82(4), 519-528.
  • Morf, LS., Gloor, R., Haag, O., Haupt, M., Skutan, S., Di Lorenzo, F., & Böni, D., (2013), “Precious metals and rare earth elements in municipal solid waste –sources and fate in a Swiss incineration plant”, Waste Management, 33(3), 634-644.
  • Nordberg, GF., Nogawa, K., and Nordberg, M., (2015), Cadmium. Nordberg, GF., Fowler, BA., Nordberg, M., (edt.), Handbook on the Toxicology of Metals, (667-716), Europe, Academic Press.
  • Rajor, A., Xaxa, M., Mehta, R., & Kunal, A., (2012), “An overview on characterization, utilization and leachate analysis of biomedical waste incinerator ash”, Journal of Environmental Management, 108, 36-41.
  • Schuhmacher, M., Domingo, JL., Agramunt, MC., Bocio, A., & Muller, L., (2002), “Biological monitoring of metals and organic substances in hazardous-waste incineration workers”, International Archives Occupational and Environmental Health, 75(7), 500-506.
  • Smith, DR., and Nordberg, M., (2015), General Chemistry, Sampling, Analytical Methods, And Speciation, Nordberg, GF., Fowler, BA., Nordberg, M., (edt.), Handbook on the Toxicology of Metals, (15-44), Europe, Academic Press.
  • Sommar, JN., Svensson, MK., Björ, BM., Elmståhl, SI., Hallmans, G., Lundh, T., Schön, SM., Skerfving, S., & Bergdahl, IA., (2013), “End-stage renal disease and low level exposure to lead, cadmium and mercury; a population-based, pro-spective nested case-referent study in Sweden”, Environmental Health, 12(9), 1 – 10.
  • Tellez-Plaza, M., Navas-Acien, A., Menke, A., & Crainiceanu, CM., (2012), “Cadmium exposure and all-cause and cardiovascular mortality in the U.S. general population”, Environmental Health Perspectives, 120(7), 1017-1022.
  • Valerio, F., (2008), “Review on environmental impact of solid wastes produced by municipal urban waste incinerators”, Epidemiologia e Prevenzione, 32(4-5), 244-253.
  • Wrbitzky, R., Goen, T., Letzel, S., Frank, F., & Angerer, J., (1995), “Internal exposure of waste incineration workers to organic and inorganic substances”, International Archives Occupational and Environmental Health, 68(1), 13-21.
  • Wultsch, G., Misik, M., Nersesyan, A., & Knasmueller, S., (2011), “Genotoxic effects of occupational exposure measured in lymphocytes of waste-incinerator workers”, Mutation Research-Genetic Toxicology Environmental Mutagene-sis, 720, 3-7.
  • Zhao, L., Zhang, F., Wang, K., & Zhu, J., (2008), “Chemical properties of heavy metals in typical hospital waste incinerator ashes in China”, Waste Management, 29, 1114-1121.
Toplam 36 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Derleme Makale
Yazarlar

Orkun Dalyan 0000-0003-4791-9084

Hatice Dalyan 0000-0002-3012-742X

Mehmet Pişkin 0000-0002-4572-4905

Proje Numarası FYL-2020-3180
Yayımlanma Tarihi 31 Ağustos 2021
Kabul Tarihi 29 Ağustos 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 4 Sayı: 2

Kaynak Göster

APA Dalyan, O., Dalyan, H., & Pişkin, M. (2021). Atık Yakma Fırını Çalışanlarında Gözlemlenen Toksik Metallerin Biyoizlenmesi. OHS ACADEMY, 4(2), 65-78. https://doi.org/10.38213/ohsacademy.977889