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Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques

Cilt: 9 Sayı: 1 29 Haziran 2024
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Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques

Öz

Estimating blood sugar levels is a critical task in effective diabetes management. This study focuses on leveraging the power of machine learning models such as CatBoost, XGBoost, and Extra Trees Regressor, along with explainable AI techniques like SHAP values and confusion matrices, to predict blood sugar levels using Photoplethysmography (PPG) signals. The dataset used in this research is carefully selected for glucose prediction from PPG signals and consists of data from 217 individuals. Information for each individual includes laboratory glucose measurements and approximately one minute of recorded finger PPG signals. Among the various machine learning models tested, CatBoost emerged as the best-performing model in predicting blood sugar levels. The CatBoost model demonstrated its efficiency and accuracy in glucose level predictions by achieving an impressive coefficient of determination (R2) of 0.7191 and a mean absolute error (MAE) of 25.21. Feature importance analysis highlighted the significance of specific features like median deviation and kurtosis in the predictive model built with CatBoost, emphasizing their critical role in determining blood sugar levels. The inclusion of explainable AI techniques enhanced the interpretability and transparency of predictive models. In conclusion, this research underscores the potential of machine learning-based approaches in predicting blood sugar levels from PPG signals. By leveraging advanced models like CatBoost and utilizing explainable AI methods, this study paves the way for improved diabetes management through accurate, non-invasive, and data-driven predictive methodologies.

Anahtar Kelimeler

Blood Sugar Prediction, Photoplethysmography, Machine Learning, SHAP, XAI

Kaynakça

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  4. American Diabetes Association. Diagnosis and classification of diabetes mellitus, Diabetes Care, 32 (1), 62–67, 2009.
  5. O. Sevli. Diyabet hastalığının farklı sınıflandırıcılar kullanılarak teşhisi, Journal of the Faculty of Engineering and Architecture of Gazi University, 38:2 (2023) 989-1001
  6. American Diabetes Association. (2023). Standards of Medical Care in Diabetes—2023. Diabetes Care, 46(Suppl. 1): S1-S291.
  7. Lam, B. Q., Srivastava, R., Morvant, J., Shankar, S., Srivastava, R. K. 2021. Association of DM and Alcohol Abuse with Cancer: Molecular Mechanisms and Clinical Significance. Cells 2021, Vol. 10, 10(11):, 3077. https://doi.org/10.3390/CELLS10113077
  8. Quinones, S., Robert Roberts, C. C., David Cistola, C.-C., Narayan, M., Crites, S. L. 2021. Non-invasive in-vitro glucose monitoring using an optical sensor and machine searning techniques for diabetes applications, Texas.
  9. Beck, R. W., Riddlesworth, T., Ruedy, K., & Kollman, C. (2018). Continuous glucose monitoring versus usual care in patients with type 2 diabetes receiving multiple daily insulin injections: a randomized trial. Annals of Internal Medicine, 169(6), 379-387.
  10. Karon, B. S. (2016). Why is there still no international standard for glucose in blood? Clinical Chemistry and Laboratory Medicine (CCLM), 54(6), 975-977.

Kaynak Göster

APA
Adigüzel, G., Şentürk, Ü., & Polat, K. (2024). Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques. Open Journal of Nano, 9(1), 45-62. https://doi.org/10.56171/ojn.1473276
AMA
1.Adigüzel G, Şentürk Ü, Polat K. Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques. Open J. Nano. 2024;9(1):45-62. doi:10.56171/ojn.1473276
Chicago
Adigüzel, Gökhan, Ümit Şentürk, ve Kemal Polat. 2024. “Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques”. Open Journal of Nano 9 (1): 45-62. https://doi.org/10.56171/ojn.1473276.
EndNote
Adigüzel G, Şentürk Ü, Polat K (01 Haziran 2024) Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques. Open Journal of Nano 9 1 45–62.
IEEE
[1]G. Adigüzel, Ü. Şentürk, ve K. Polat, “Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques”, Open J. Nano, c. 9, sy 1, ss. 45–62, Haz. 2024, doi: 10.56171/ojn.1473276.
ISNAD
Adigüzel, Gökhan - Şentürk, Ümit - Polat, Kemal. “Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques”. Open Journal of Nano 9/1 (01 Haziran 2024): 45-62. https://doi.org/10.56171/ojn.1473276.
JAMA
1.Adigüzel G, Şentürk Ü, Polat K. Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques. Open J. Nano. 2024;9:45–62.
MLA
Adigüzel, Gökhan, vd. “Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques”. Open Journal of Nano, c. 9, sy 1, Haziran 2024, ss. 45-62, doi:10.56171/ojn.1473276.
Vancouver
1.Gökhan Adigüzel, Ümit Şentürk, Kemal Polat. Blood Glucose Level Estimation Using Photoplethysmography (PPG) Signals with Explainable Artificial Intelligence Techniques. Open J. Nano. 01 Haziran 2024;9(1):45-62. doi:10.56171/ojn.1473276