Textile-Based and Composite Wound Dressing Materials: A Review

Yıl 2025, Cilt: 8 Sayı: 5, 2594 - 2616, 15.12.2025

Emel Ceyhun Sabır

https://doi.org/10.47495/okufbed.1473438

Öz

In this study, current wound dressing materials including textile and engineering materials; species have been extensively researched and compared for their performance in wound healing. It has been observed that the studies in the literature are generally on a certain artificial tissue, wound type or wound dressing. In this thesis study, current studies in the field of wound dressing and artificial tissue, which are widely covered in the literature, are given within the scope of textile surfaces. First of all, wounds due to loss of healthy epithelial tissue in the body and their types, wound healing were examined in order to evaluate the performance of defined wound dressings, and studies on wound dressing types, textile and composite based wound dressing materials, their properties and the performance expected from wound dressings were evaluated. In the continuation of the study, modern wound dressings and modern dressings were given according to the materials from which they are produced and the active ingredient content of natural and artificial dressings.

Anahtar Kelimeler

Wound dressings , textile , textile composites , Medical textiles

Tekstil Bazlı ve Kompozit Yapıda Yara Örtücü Malzemeler: Bir Derleme

Öz

Bu çalışmada, tekstil ve mühendislik malzemelerini içeren yara örtücü güncel malzemeler; türleri, yara iyileştirmedeki performanslarına yönelik geniş kapsamlı olarak araştırılmış ve karşılaştırılmıştır. Literatürdeki araştırmaların genellikle belirli bir yapay doku, yara çeşidi veya yara örtüsü üzerine olduğu görülmüştür. Çalışmada öncelikle, vücutta sağlıklı epitel doku kaybından dolayı oluşan yaralar ve çeşitleri tanımlanmış, yara örtücülerin performasını değerlendirebilmek için yaranın iyileşmesi incelenmiş, yara örtücü çeşitleri, tekstil ve kompozit bazlı yara örtücü malzemeleri, özellikleri ve yara örtücülerden beklenen performansa yönelik çalışmalar değerlendirilmiştir. Çalışmanın devamında, doğal ve yapay yara örtücü çeşitlerini üretildikleri malzemelere göre, etken madde içeriğine göre modern yara örtücüler şeklinde modern yara örtücüler verilmiştir.

Anahtar Kelimeler

Yara örtücüler , Medikal tekstil , Teknik tekstil , Tekstil kompozitleri

Kaynakça

• Anonim. Medical textiles market size, share, and trends 2025 to 2034. https://www.precedenceresearch.com/medical-textiles-market, 2025. (Erişim 21 Nisan 2025)
• Abdelhady MM. Preparation and characterization of chitosan/zinc oxide nanoparticles for imparting antimicrobial and UV protection to cotton fabric. International Journal of Carbohydrate Chemistry 2012; 12.
• Abdel-Mohsen AM., Abdel-Rahman RM., Hrdina R., Imramovsky A., Burgert L., Aly AS. Antibacterial cotton fabrics treated with core-shell nanoparticles. International Journal of Biological Macromolecules 2012; 50(5): 1245-1253.
• Adhirajan N., Shanmugasundaram N., Shanmuganathan S., Babu M. Collagen-based wound dressing for doxycycline delivery: in-vivo evaluation in an infected excisional wound model in rats. Journal of Pharmacy and Pharmacology 2009; 61(12): 1617-1623.
• Aras O., Kazancı M. Kullanılan farklı çözücülerin ipek fibroin-pva kompozit süngerlerin yapısına olan etkisi. Tekstil ve Mühendis 2019; 26(115): 224-232.
• Arif D., Niazi MBK., Ul-Haq N., Anwar MN., Hashmi E. Preparation of antibacterial cotton fabric using chitosan-silver nanoparticles. Fibers and Polymers 2015; 16(7): 1519-1526.
• Ather and Harding. Wound management and dressing, Rajendran, S. (Ed.). Advanced textiles for wound care. The Textile Institute Book Series, Second Ed. 2019; Woodhead Publishing.
• Boateng JS., Matthews KH., Stevens HN., Eccleston GM. Wound healing dressings and drug delivery systems: a review. Journal of Pharmaceutical Sciences 2008; 97(8): 2892-2923.
• Bruin P., Jonkman MF., Meijer HJ., Pennings AJ. A new porous polyetherurethane wound covering. Journal of Biomedical Materials Research 1990; 24(2): 217-226.
• Bužarovska A., Selaru A., Serban M., Pircalabioru GG., Costache M., Cocca M., Gentile G., Averous L., Dinescu S. Biobased multiphase foams with ZnO for wound dressing applications. Journal of Materials Science 2023; 58(46): 17594-17609.
• Candan C. https://www.tekstilteknik.com.tr/koku-buyuk-problem/ (Erişim Nisan 2018).
• Chan KT., Song X., Shen L., Liu N., Zhou X., Cheng L., Chen J. Nisin and its application in oral diseases. Journal of Functional Foods 2023; 105: 105559.
• Chen XJ., LV AF., Gao J., Wang L. Moisture dressings: A new revolution in wound care, Proceedings of 2012 International Forum on Biomedical Textile Materials. June 8-9, 2012, Shanghai, China, 2012;243-246.
• Christgau M., Caffesse RG., Schmalz G., D'Souza RN. Extracellular matrix expression and periodontal wound‐healing dynamics following guided tissue regeneration therapy in canine furcation defects. Journal of Clinical Periodontology 2007; 34(8): 691-708.
• Chu HQ., Xiong H., Zhou XQ., Han F., Wu ZG., Zhang P., Huang XW., Cui YH. Aminoglycoside ototoxicity in three murine strains and effects on NKCC1 of striavascularis. Chinese Medical Journal 2006;119(12): 980-985.
• Clark M. Alginates in dressings and wound management. In Alginates and Their Biomedical Applications 2017; (pp. 213-22). Singapore: Springer Singapore.
• Das S., Baker AB. Biomaterials and nanotherapeutics for enhancing skin wound healing. Frontiers in Bioengineering and Biotechnology 2016; 4: 82.
• Ersoy Y., Duran M., Tayyar AE. Tıbbi tekstiller ve yara örtüsü. Düzce Üniversitesi Bilim ve Teknoloji Dergisi 2015; 3: 451-458.
• Ertekin G., Marmaralı A. The compression characteristic of weft knitted spacer fabrics. Journal of Textile & Apparel/Tekstil ve Konfeksiyon 2012; 22(4).
• Gouda M., Hebeish A. Preparation and evaluation of cuo/chitosan nanocomposite for antibacterial finishing cotton fabric. Journal of Industrial Textiles 2010; 39(3): 203-214.
• Gunes OC., Ziylan Albayrak A. Antibacterial polypeptide nisin containing cotton modified hydrogel composite wound dressings. Polymer Bulletin 2021;78(11): 6409-6428.
• Gupta B., Agarwal R., Alam MS. Textile-based smart wound dressing, Indian Journal of Fibre & Textile Research 2010; 35: 174-187.
• Hanna JR., Giacopelli JA. A review of wound healing and wound dressing products. The Journal of Foot and Ankle Surgery 1997; 36(1): 2-14.
• Horch RE., Bleiziffer O., Kneser U. Physiology and wound healing. Plastic and Reconstructive Surgery 2010; (pp. 3-10), London: Springer London.
• Hargis A., Yaghi M., Bermudez NM., Gefen A. Foam dressings for wound healing. Current Dermatology Reports 2024; 13(1): 28-35.
• Hu J., Xiao ZB., Zhou RJ., Ma SS., Li Z., Wang MX. Comparison of compounded fragrance and chitosan nanoparticles loaded with fragrance applied in cotton fabrics. Textile Research Journal 2011; 81(19): 2056-2064.
• Islam S., Arnold L., Padhye R. Application of chitosan on wool-viscose nonwoven for wound dressing, Journal of Biobased Materials and Bioenergy 2013; 7(4): 439-443.
• Jayakumar R., Prabaharan M., Kumar PS., Nair SV., Tamura HJBA. Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnology Advances 2011; 29(3): 322–337.
• Jiang S., Deng J., Jin, Y., Qian B., Lv W., Zhou Q., Mei E., Neisiany RE., Liu Y., You Z., Pan J. Breathable, antifreezing, mechanically skin-like hydrogel textile wound dressings with dual antibacterial mechanisms. Bioactive Materials 2023; 21: 313-323.
• Joshi M., Purwar R. Composite dressings for wound care, In Advanced Textiles for Wound Care, Woodhead Publishing Series in Textiles 2019; 313-327.
• Khan R., Haider S., Wahit MU., Rahman SU., Hameed S., Haider A., Aqif M., Bukhari IA., Abd Razak SI. Preparation of amine-functionalized polyacrylonitrile-TiO2-chitosan multilayer nanofibers as a potential wound dressing: Characterization and investigation of in vitro cell viability, proliferation and antibacterial study. International Journal of Biological Macromolecules 2025; 141006.
• Kim JO., Choi JY., Park JK., Kim JH., Jin SG., Chang SW. Development clindamycin-loadedwound dressing with polyvinylalcohol and sodiumalginate. Biological and Pharmaceutical Bulletin 2008; 31(12): 2277-2282.
• Kumar TRS., Bai MV., Krishnan LK. A freeze-dried fibrin disc as a biodegradable drug release matrix. Biologicals 2004; 32(1): 49-55.
• Kuram E. Natural fiber-based polymer composites for biomedical applications. Journal of Biomaterials 2024; 1-58.
• Kurtoğlu AH., Karataş A. Yara tedavisinde güncel yaklaşımlar: modern yara örtüleri. Ankara Eczacılık Fakültesi Dergisi 2009; 38(3): 211-232.
• Lazovic G., Colic M., Grubor M., Jovanovic M. The application of collagen sheet in open wound healing, Ann. Burns Fire Disasters 2005; 18: 151-158.
• Lee SM., Park IK., Kim YS., Kim HJ., Moon H., Mueller S., Jeong YI. Physical, morphological, and wound healing properties of a polyurethane foam-film dressing. Biomaterials Research 2016; 20(1): 15.
• Luo Y., Kirker KR., Prestwich GD. Crosslinked hyaluronic acid hydrogel films: New biomaterials for drug delivery. Journal of Controlled Release 2000; 69: 169-184.
• Lyu Y., Yu L., Qi L., Meng J., Wang Y., Liu Y., Xue T., Zhi C. Construction of 3D-fabric-based triple-decker agar/sodium alginate/Ca2+ dual-network composite for wound dressing. International Journal of Biological Macromolecules 2025; 304: 140883.
• Mai LM., Lin CY., Chen CY., Tsai YC. Synergistic effect of bismuth subgallate and borneol, the major components of Sulbogin® on the healing of skin wound. Biomaterials 2003; 24(18): 3005-3012.
• Mo M., Wu C., Chen Y. Bacterial cellulose-based superabsorbent hydrogel for wet wound dressing. Molecules 2025; 30(3): 737.
• Montaser A., Rehan M., El-Senousy WM., Zaghloul S. Designing strategy for coating cotton gauze fabrics and its application in wound healing. Carbohydrate Polymers 2020; 244: 116479.
• Oh EJ., Park KT., Kim KS., Kim JS., Yang JA., Kong JH. Target specific and long-acting delivery of protein, peptide and nucleotide therapeutics using hyaluronic acid derivatives. Journal of Controlled Release 2010; 141(1): 2-12.
• Paul W., Sharma C. Chitosan and alginate wound dressings: a short review. Trends Biomaterials Artificial Organs 2004; 18(1): 18-23.
• Pinho E., Soares G. Functionalization of cotton cellulose for improved wound healing. Journal of Materials Chemistry B 2018; 6: 1887-1898.
• Pinho E., Soares G., Henriques M., Grootveld M. Antibacterial activity of textiles for wound treatment. AATCC Journal of Research 2015; 2(5): 1-7.
• Patil PP., Reagan MR., Bohara RA. Silk fibroin and silk-based biomaterial derivatives for ideal wound dressings. International Journal of Biological Macromolecules 2020; 164: 4613-4627.
• Punjataewakupt A., Aramwit P. Wound dressing adherence: A review, Journal of Wound Care 2022; 31(5): 406-423.
• Purna SK., Babu M. Collagen based dressings - A review. Burns 2000; 26(1): 54–62.
• Qin Y. The characterization of alginate wound dressings with different fiber and textile structures. Journal of Applied Polymer Science 2006; 100: 2516-2520.
• Rao BR. Kumar R., Haque S, Kumar JM., Rao TN, Kothapalli RV., Patra CR. Ag2[Fe(CN)5NO]-fabricated hydrophobic cotton as a potential wound healing dressing: An in vivo approach. ACS Applied Materials Interfaces 2021; 13(9): 10689-10704.
• Resmi G., Amsamani S. Antibacterial and wound healing efficacy of Chromolaena odorata treated dressings. Indian Journal of Fibre Textile Research 2022; 47(1): 78-86.
• Rodeigues M., Thilagavati, G. Development and study of textile–based hydrogel wound dressing material, Industria Textila 2022; 73(1): 40-47.
• Ruszczak Z., Friess W. Collagen as a carrier for on-site antibacterial drugs. Advanced Drug Delivery Reviews 2003; 55(12), 1679-1698.
• Sağlam M., Baran Ş. Tekstil sektörünün geleceği: Mevcut durum değerlendirmesi ve gelecek öngörüleri 2025; MÜSİAD Teknik Rapor, ss.1-88, MÜSİAD Tekstil, Deri ve Hazır Giyim Sektör Kurulu Raporu, URL:https://avesis.ticaret.edu.tr/yayin/baa489af-dc6d-4119-9187-abfafe32fe79/tekstil-sektorunun-gelecegi-mevcut-durum-degerlendirmesi-ve-gelecek-ongoruleri (Erişim 13 Mayıs 2025).
• Sabır EC., Taş M., Küçükgülmez A. Karides atıklarından Elde Edilen Kitosan Biyopolimerinin Yünlü Kumaşların Antibakteriyel Özellikleri Üzerine Etkisi. Çukurova Üniversitesi Mühendislik-Mimarlık Fakültesi Dergisi 2017; 32(3): 47-54.
• Schultz GS., Sibbald RG., Falanga V., Ayello EA., Dowsett C., Harding K., Romanelli M., Stacey MC., Teot L., Vanscheidt W. Wound bed preparation: A systematic approach to wound management. Wound Repair and Regeneration 2003; 11(1): 1-28.
• Sinno H., Prakash S. Complements and the wound healing cascade: an updated review. Plastic Surgery International 2013; 1: 146764.
• Sorourian G., Pourmadadi M., Yazdian F., Rashedi H., Nigjeh MN., Sorourian M., Pandey S. Preparation of antibacterial nanofiber nanocomposites based on bacterial cellulose. BioNanoScience 2025; 15(2): 238.
• Söğüt R., Sabır EC. Yara örtücü malzemeler. 9. Uluslararası Mühendislik ve Teknoloji Kongresi, 16-17 Nisan 2023, İstanbul.
• Söğüt R. Yara örtücü ve yapay doku alanlarında tekstil kompozitlerinin kullanımı ve performans araştırması. Çukurova Üniversitesi, Fen Bilimleri Enstitüsü, Tekstil Mühendisliği Anabilim Dalı, Yüksek Lisans Tezi 2021; (Ulusal Tez Merkezi Tez No: 672623).119 sayfa. Adana/Türkiye.
• Speakman JB., Chamberlain NH. The production of rayon from alginic acid. Journal of the Society of Dyers and Colourists 1944; 60(10): 264-272.
• Steenfos HH. Growth factors and wound healing. Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 1994; 28(2): 95-105.
• Suarato G., Bertorelli R., and Athanassiou A. Borrowing from nature: Biopolymers and biocomposites as smart wound care materials. Front Bioeng Biotechnol 2018; 6 (Oct): 1–11.
• Sun XZ., Wu JZ., Wang HD., Guan C. Thermosensitive Cotton textile loaded with cyclodextrin-complexed curcumin as a wound dressing. Fibers and Polymers 2021; 22(9): 2475–2482.
• Tassw DF., Birlie B., Mamaye T. Nanotechnologies past, present and future applications in enhancing functionality of medical textiles: a review. The Journal of The Textile Institute 2024; 1-21.
• Thomas V, Bajpai M, Bajpai SK. In situ formation of silver nanoparticles within chitosan-attached cotton fabric for antibacterial property. Journal of Industrial Textiles 2011; 40(3): 229-45.
• Thomason HA., Lovett JM., Spina CJ., Stephenson C., Mcbain AJ., Hardman MJ. Silver oxysalts promote cutaneous wound healing independent of infection. Wound Repair Regen 2018; 26: 144–152. doi: 10.1111/wrr.12627
• Tyrone JW., Mogford JE., Chandler LA., Ma C., Xia Y., Pierce GF., Mustoe TA. Collagen-embedded platelet-derived growth factor DNA plasmid promotes wound healing in a dermal ulcer model. Journal of Surgical Research 2000; 93(2): 230-236.
• Ueno H., Yamada H., Tanaka I., Kaba N., Matsuura M., Okumura M., Kadosawa T., Fujinaga T. Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs. Biomaterials 1999; 20: 1407-1414.
• Üreyen ME., Çavdar A., Koparall AS., Doğan A. Yeni geliştirilen gümüş katkılı antimikrobiyal tekstil kimyasalı ve bu kimyasal ile işlem görmüş kumaşların antibakteriyel performansları. Tekstil ve Mühendis 2008; 15(69): 25-31.
• Wang XD., Russel SJ. Antimicrobial textile materials in healthcare and medical wound dressings, Proceedings of 2009 International Textile Science and Technology Forum 2010; 10-17.
• Xu D., Feng Y., Song M., Zhong X., Li J., Zhu Z., Wang J. Smart and bioactive electrospun dressing for accelerating wound healing. Chemical Engineering Journal 2024; 496: 153748.
• Yang Y., Hu H. Spacer fabric-based exuding wound dressing–Part II: Comparison with commercial wound dressings. Textile Research Journal 2017; 87(12): 1481-1493.
• Yang Y., Bechtold T., Redl B., Caven B., Hu H. A novel silver-containing absorbent wound dressing based on spacer fabric. Journal of Materials Chemistry B 2017; 5(33): 6786-6793.
• Yıldırım N., Küçük İ. Sarı kantaron (Hypericum perforatum) katkılı kitosan ve jelatin esaslı yara örtücü filmlerinin üretimi ve karakterizasyonu (Preparing and characterization of St.John’s Wort (Hypericum perforatum) incorporated wound dressing films based on chitosan and gelatin), Journal of the Faculty of Engineering and Architecture of Gazi University 2020; 35(1): 127-135
• Yuan N., Shao K., Huang S., Chen C. Chitosan, alginate, hyaluronic acid and other novel multifunctional hydrogel dressings for wound healing: A review, International Journal of Biological Macromolecules 2023; 240: 124321.
• Zheng L., Li S. Luo J., Wnag X. Latest advances on bacterial cellulose-based antibacterial materials as wound dressings. Frontiers in Bioengineering and Biotechnology 2020; 8: 593768.
• Zong S., Zhang H., Ma Z., Xin Q., Lu Y., Shi P. Qin M., Li J., Sing C. Recent advancements in wound management: Tailoring super wettable bio-interfaces. Frontiers in Bioengineering and Biotechnology 2022; 10: 1106267.