IMMUNOMODULATORY EFFECTS OF MORINGA OLEIFERA LEAF MEAL (MOLM) AGAINST NEWCASTLE DISEASE IN BROILERS

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ABSTRACT Moringa oleifera meal can serve as a natural antimicrobial agent and a feed supplement supplying nutrients for rural and commercial poultry. Recently Moringa have wide range of application as a medicine, protein supplement and as an antioxidant in poultry. Moringa mainly composed of carbohydrates (38%), 27%, protein (27%), moisture (6%) and fibre (18%). The present study was planned to check efficacy of Moringa oleifera leaf meal (MOLM) for immunomodulatory effects in Broilers whilst it has been established already that there isn’t any deleterious effect in M. oleifera which are found in chemical drugs. 144 birds were divided into 4 groups having 12 birds of each and subdivided into groups of 12. Such that treatment groups were D; receiving 0%, divided into replicates D1, D2, D3 while similar divisions of group A, B and C received 2, 4 and 6 % of MOLM infused in their feed as an additive supplement. The birds were slaughtered at 14th, 21th and 35th day and blood as well as serum was collected for the sake of hematological parameters and to check the antibody titre using HA/HI checking for effectiveness of immune system at producing antibodies against Newcastle Disease, which the birds were vaccinated against. Maximum weight gain was observed in broilers fed diet B while lowest weight gain was observed in birds fed diet D, which was a control group. Maximum feed intake was observed in broilers fed diet A while lowest feed intake was observed in birds fed diet D, which was a control group. Significantly, better feed conversion ratio was observed in birds fed diet B whereas the highest feed conversion ratio (FCR) was observed in broilers fed diet without Moringa oleifera supplementations. The highest antibody level was found in the birds of group B, while lowest level was found in the broilers of group D. Maximum spleen weight was observed in birds fed diet group C and D while lowest weight was observed in birds fed diet A. Maximum thymus weight was observed in birds fed diet B and C. Bursa weight was observed in birds fed diet A and D while lowest weight was observed in birds fed diet C. There was no significant difference (P>0.05) on hematological profile among groups. All the collected data was analyzed by statistical software Minitab Inc. 2010. Minitab Statistical Software (Release 17). State College, PA. The data thus, obtained was subjected to CRD for analysis of variance. It was concluded that Moringa infused in feed does enhance immune parameters of broilers, making them better at combating diseases, making Moringa a viable dietary supplement for commercial poultry. It was also found that the optimal dose of Moringa in MOLM is 4g/kg feed

Anahtar Kelimeler

• moringa oliefera
• broilers
• Newcastle disease
• immunity

Kaynakça

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