SUCUL MODEL ORGANİZMALAR VE BİYOTEKNOLOJİDE KULLANIMI

Yıl 2013, Cilt: 28 Sayı: 2, 101 - 107, 27.05.2013

Filiz Kutluyer , Ercüment Aksakal

Öz

Model organizmalar; in vitro koşullarda üretilen ve üretiminin sürdürülmesi kolay olan, kısa jenerasyon aralığına sahip, deneysel avantajları olan ve biyolojik olayların araştırılmasında kullanılan canlılardır. İnsan genomu ile karşılaştırıldığında homolojisi oldukça yüksek ancak genom boyu küçük olan model organizmalar insan üzerinde çalışılması mümkün olmayan her türlü deneyde kullanılabilirler. Son yıllarda zebra balığı (Danio reiro), medaka balığı (Oryzias latipes) ve balon balığı (Fugu rubripes) gibi bazı sucul canlılar model organizma olarak kullanılmaktadır. Bu derlemede sucul model organizmalar ve biyoteknolojik çalışmalarda kullanım alanları hakkında bilgiler sunulmuştur.

Anahtar Kelimeler

Sucul model organizma, biyoteknoloji

SUCUL MODEL ORGANİZMALAR VE BİYOTEKNOLOJİDE KULLANIMI

Öz

Model organizmalar; in vitro koşullarda üretilen ve üretiminin sürdürülmesi kolay olan, kısa jenerasyon aralığına sahip, deneysel avantajları olan ve biyolojik olayların araştırılmasında kullanılan canlılardır. İnsan genomu ile karşılaştırıldığında homolojisi oldukça yüksek ancak genom boyu küçük olan model organizmalar insan üzerinde çalışılması mümkün olmayan her türlü deneyde kullanılabilirler. Son yıllarda zebra balığı (Danio reiro),, medaka balığı (Oryzias latipes) ve balon balığı (Fugu rubripes) gibi bazı sucul canlılar model organizma olarak kullanılmaktadır. Bu derlemede sucul model organizmalar ve biyoteknolojik çalışmalarda kullanım alanları hakkında bilgiler sunulmuştur.

AQUATIC MODEL ORGANISMS AND THEIR USE IN BIOTECHNOLOGY

Model organisms are preferable species to study biological phenomena due to their features that they can be produced in vitro easily and maintained continuously and they have short generation intervals and some experimental advantages. Compared to human genome, model organisms, which have very high homology and small genome size, can be used in experiments that have been impossible to study on human beings. In recent years, aquatic model organisms such as zebra fish (Danio reiro), medaka fish (Oryzias latipes) and puffer fish (Fugu rubripes) are used as model organism. In this review, information on aquatic model organisms and their utilitiy in biotechnological researches are presented.

Anahtar Kelimeler

Sucul model organizma, biyoteknoloji

Kaynakça

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