Past, Present, Future and Environmental Treatment of the Pesticide Triclosan
Yıl 2024,
Cilt: 14 Sayı: 2, 191 - 212, 31.12.2024
Elif Kağızman
,
Şeyda Fikirdesici Ergen
,
Burcu Taştan
Öz
Triclosan [5-chloro-2-(2,4-dichlorophenoxy) phenol] or with its trade name “Irgasan” is known as a broad-spectrum powerful antimicrobial agent. It is registered as a “pesticide” by the United States Environmental Protection Agency (USEPA). It is estimated that around 450 tonnes of triclosan are used each year in Europe. 85% of triclosan is widely used in personal care products, 5% in the textile industry, and 10% in the production of plastics and food contact materials. Due to its extensive use, accumulation of triclosan has been detected in humans and the environment. Triclosan is an environmentally toxic substance, studies are being conducted on its toxicity and its toxic effect mechanism is elucidated in different living groups. This article reviews data on triclosan's environmental fate, exposure in humans and other organisms, efficacy of antimicrobial activity, toxicity, and environmental treatment mechanisms.
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Triklosan Pestisitinin Dünü, Bugünü, Geleceği ve Çevresel Arıtımı
Yıl 2024,
Cilt: 14 Sayı: 2, 191 - 212, 31.12.2024
Elif Kağızman
,
Şeyda Fikirdesici Ergen
,
Burcu Taştan
Öz
Triklosan [5-chloro-2-(2,4-dichlorophenoxy) phenol] ya da ticari ismiyle “Irgasan” geniş spektrumlu güçlü bir antimikrobiyal ajan olarak bilinmektedir. Amerika Birleşik Devletleri Çevre Koruma Ajansı (USEPA) tarafından “pestisit” olarak tescillenmiştir. Avrupa’da her yıl yaklaşık 450 ton triklosanın kullanıldığı tahmin edilmektedir. Triklosanın % 85’i kişisel bakım ürünlerinde, % 5’i tekstil endüstrisinde ve % 10’u da plastik ve gıda ile temas eden maddelerin üretiminde yaygın olarak kullanılmaktadır. Kapsamlı kullanımı nedeniyle, insanlarda ve çevrede triklosan birikimi tespit edilmiştir. Triklosan çevresel açıdan toksik bir madde olup, toksisitesi ile çalışmalar yürütülmekte ve farklı canlı gruplarında toksik etki mekanizması aydınlatılmaktadır. Bu makale, triklosan’ın çevresel akıbeti, insan ve diğer canlı gruplarında maruziyeti, anti-mikrobiyal aktivitenin etkinliği, toksisitesi ve çevresel arıtım mekanizmaları hakkındaki verileri gözden geçirmektedir.
Etik Beyan
Bu makalenin yayınlanmasıyla ilgili herhangi bir etik sorun bulunmamaktadır.
Destekleyen Kurum
Bu çalışma 122Z742 nolu TÜBİTAK 1001 projesi kapsamında hazırlanmıştır.
Kaynakça
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