Araştırma Makalesi
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Solid meme kitlelerinin karakterize edilmesinde elastografinin rolü

Yıl 2019, Cilt: 11 Sayı: 2, 200 - 206, 01.06.2019
https://doi.org/10.21601/ortadogutipdergisi.435904

Öz

Amaç: Bu prospektif çalışmada ultrasonografide BI-RADS (Meme görüntüleme ve rapor sistemi) 3, BI-RADS 4, BI-RADS 5 olarak değerlendirilen lezyonlar nedeniyle eksizyonel biyopsiye yönlendirilen hastaların histopatolojik inceleme bulgularının elastografi elastikiyet indeksi değerleri ile korelasyonu, lezyonların malign-benign ayrımına yönelik olarak elastografinin etkinliğinin araştırılması ve elastikiyet indeksi cut-off değerinin belirlenmesi amaçlanmıştır.
Gereç ve Yöntem: 1 Kasım 2008 ile 28 Şubat 2009 tarihleri arasında Ankara Dr. Abdurrahman Yurtaslan Onkoloji Eğitim ve Araştırma Hastanesi Radyoloji Kliniği’ne yönlendirilen ve meme ultrasonografisinde solid kitle saptanan 70 kadın hasta incelendi. Meme kitlelerinin renk skoru ve elastikiyet indeksi değerleri değerlendirildi.
Bulgular: İstatistiksel olarak lezyonların malign-benign ayrımına yönelik elastikiyet indeksi cut-off değeri 4,05 olarak hesaplanmıştır. Ayrıca, aynı ayrıma yönelik olarak elastografinin sensitivitesi ve spesifitesi ayrı ayrı %90 ve %97 olarak hesaplanırken, pozitif prediktif değeri ve negatif prediktif değeri ise ayrı ayrı %90 ve %97,5 olarak belirlenmiştir.
Sonuç: Gerçek zamanlı elastografi şüpheli meme lezyonlarının benign malign ayırımında uygulanabilecek yüksek sensitiviteye ve spesifiteye sahip olduğu kadar, yüksek pozitif ve negatif prediktif değerlere sahip oldukça yararlı bir görüntüleme tekniğidir.

Kaynakça

  • Sariego J, Zrada S, Byrd M, Matsumoto T. Breast cancer in young patients. Am J Surg 1995; 170: 243-5.
  • Peer PG, Verbeek AL, Ravunac MM, ve ark. Prognosis of younger and older patients with early breast cancer. Br J Cancer 1996; 73: 382-5.
  • Costanza ME, Edmiston KL. Breast cancer screening: early recognition. Compr Ther 1997; 23: 7-12.
  • Stavros AT. Breast Ultrasound, Philadelphia, USA, Lippincott Williams, Wilkins, 2004.
  • Meyer JE, Kopans DB, Stomper PC, Lindfors KK. Occult breast abnormalities: percutaneous preoperative needle localization. Radiology 1984; 150: 335-7.
  • Haydaroğlu A, Dubova S, Özsaran Z, Bölükbaşı Y, Yılmaz R, Kapkaç M, Özdedeli E. Ege Üniversitesinde Meme Kanserleri. 3897 olgunun değerlendirilmesi. Meme Sağlığı Derg 2005; 1: 6-7.
  • Sadler RG, Ko CM, Cohn AJ, White M, Weldon R, Wu P. Breast cancer knowledge, attitudes, and screening behaviors among African American women: the Black cosmetologists promoting health program, BioMed Central Public Health 2007; 7: 57.
  • Ko CM, Sadler GR, Ryujin L, Dong A. Filipina American women’s breast cancer knowledge, attitudes, and screening behaviors, BioMed Central Public Health 2003; 3.
  • Insana MF, Pellot-Barakat C, Sridhar M, Lindfors KK. Viscoelastic imaging of breast tumor microenvironment with ultrasound. J Mammary Gland Biol Neoplasia 2004; 9: 393-404.
  • Hall TJ, Zhu Y, Spalding CS. In vivo real-time freehand palpation imaging. Ultrasound Med Biol 2003; 29: 427-35.
  • Garra BS, Cespedes EI, Ophir J, ve ark. Elastography of breast lesions: initial clinical results. Radiology 1997; 202: 79-86.
  • Krouskop TA, Wheeler TM, Kallel F, Garra BS, Hall T. Elastic moduli of breast and prostate tissues under compression. Ultrason Imaging 1998; 20: 260-74.
  • Tohno E, Ei Ueno Current improvements in breast ultrasound, with a special focus on elastography. Breast Cancer 2008; 15: 200-4. Doi 10.1007/s12282-008-0052-1.
  • Itoh A, Ei Ueno. Breast disease: clinical application of US elastography for diagnosis. Radiology 2006; 239: 341-50.
  • Zhi H, Ou B, Luo BM, ve ark. Comparison of ultrasound elastography, mammography, and sonography in the diagnosis of solid breast lesions. J Ultrasound Med 2007; 26: 807-15.

The role of elastography in the characterization of solid breast masses

Yıl 2019, Cilt: 11 Sayı: 2, 200 - 206, 01.06.2019
https://doi.org/10.21601/ortadogutipdergisi.435904

Öz

Purpose: In this prospective study, it is aimed to correlate the histopathological evaluation findings of the patients having lesions referred for excisional biopsy due to BI-RADS (Breast Imaging Reporting and Data System) 3, BI-RADS 4, BI-RADS 5 lesions detected by ultrasonography, with their elastography elasticity index values, to investigate the role of elastography and to determine elastography elasticity index cut-off value for the malignant benign differentiation of these lesions.
Material and Method: In 1 November 2008-28 February 2009, seventy female patients referred to the Department of Radiology in Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, who were found to have solid breast lesions by ultrasonography, were evaluated. The colour score and elasticity index values of the masses were assessed.
Results: Statistically, elasticity index cut-off value for the malignant-differentiation of the lesions was calculated as 4.05. Also for the same differentiation, the sensitivity and specificity of elastography were calculated as 90% and 97%, respectively, whereas positive predictive value and negative predictive value were determined as 90% and 97.5%, respectively.
Conclusion: Real-time elastography is a quite useful imaging technique, that is useful for benign malignant differentiation of suspicious breast lesions with high sensitivity and specificity as well as high positive and negative predictive values.

Kaynakça

  • Sariego J, Zrada S, Byrd M, Matsumoto T. Breast cancer in young patients. Am J Surg 1995; 170: 243-5.
  • Peer PG, Verbeek AL, Ravunac MM, ve ark. Prognosis of younger and older patients with early breast cancer. Br J Cancer 1996; 73: 382-5.
  • Costanza ME, Edmiston KL. Breast cancer screening: early recognition. Compr Ther 1997; 23: 7-12.
  • Stavros AT. Breast Ultrasound, Philadelphia, USA, Lippincott Williams, Wilkins, 2004.
  • Meyer JE, Kopans DB, Stomper PC, Lindfors KK. Occult breast abnormalities: percutaneous preoperative needle localization. Radiology 1984; 150: 335-7.
  • Haydaroğlu A, Dubova S, Özsaran Z, Bölükbaşı Y, Yılmaz R, Kapkaç M, Özdedeli E. Ege Üniversitesinde Meme Kanserleri. 3897 olgunun değerlendirilmesi. Meme Sağlığı Derg 2005; 1: 6-7.
  • Sadler RG, Ko CM, Cohn AJ, White M, Weldon R, Wu P. Breast cancer knowledge, attitudes, and screening behaviors among African American women: the Black cosmetologists promoting health program, BioMed Central Public Health 2007; 7: 57.
  • Ko CM, Sadler GR, Ryujin L, Dong A. Filipina American women’s breast cancer knowledge, attitudes, and screening behaviors, BioMed Central Public Health 2003; 3.
  • Insana MF, Pellot-Barakat C, Sridhar M, Lindfors KK. Viscoelastic imaging of breast tumor microenvironment with ultrasound. J Mammary Gland Biol Neoplasia 2004; 9: 393-404.
  • Hall TJ, Zhu Y, Spalding CS. In vivo real-time freehand palpation imaging. Ultrasound Med Biol 2003; 29: 427-35.
  • Garra BS, Cespedes EI, Ophir J, ve ark. Elastography of breast lesions: initial clinical results. Radiology 1997; 202: 79-86.
  • Krouskop TA, Wheeler TM, Kallel F, Garra BS, Hall T. Elastic moduli of breast and prostate tissues under compression. Ultrason Imaging 1998; 20: 260-74.
  • Tohno E, Ei Ueno Current improvements in breast ultrasound, with a special focus on elastography. Breast Cancer 2008; 15: 200-4. Doi 10.1007/s12282-008-0052-1.
  • Itoh A, Ei Ueno. Breast disease: clinical application of US elastography for diagnosis. Radiology 2006; 239: 341-50.
  • Zhi H, Ou B, Luo BM, ve ark. Comparison of ultrasound elastography, mammography, and sonography in the diagnosis of solid breast lesions. J Ultrasound Med 2007; 26: 807-15.
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma makaleleri
Yazarlar

Rasime Pelin Kavak 0000-0001-9782-0029

Nazan Çiledağ Bu kişi benim

Kemal Niyazi Arda 0000-0002-2502-0513

Elif Aktaş Bu kişi benim

Füsun Ardıç Bu kişi benim 0000-0002-3342-3443

Yayımlanma Tarihi 1 Haziran 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 11 Sayı: 2

Kaynak Göster

Vancouver Kavak RP, Çiledağ N, Arda KN, Aktaş E, Ardıç F. Solid meme kitlelerinin karakterize edilmesinde elastografinin rolü. otd. 2019;11(2):200-6.

e-ISSN: 2548-0251

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