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Akciğer Kanseri Tanılı Hastalarda İrritable Barsak Sendromu Sıklığı

Yıl 2016, Cilt: 8 Sayı: 1, 36 - 39, 01.03.2016

Öz

Amaç: İrritable barsak sendromu IBS barsağın fonksiyonel bir hastalığıdır. Akciğer kanseri en sık görülen kanser türlerinden biridir. IBS sigara içiciliği arasındaki ilişki tartışmalıdır. Siagra içiciliği akciğer kanserlerinin %90’ından sorumludur. Biz bu çalışmamızda yeni tanı konmuş akciğer kanseri hastalarında IBS görülme sıklığını, sigara içimi ve patolojik alt tipleri ilişkili olup olmadığını ortaya koymayı amaçladık.Yöntem ve Gereçler: Sakarya Üniversitesi İç Hastalıkları Anabilim Dalı Tıbbi Onkoloji Kliniğine 1 Ocak-31 Aralık 2014 tarihleri arasında Akciğer kanseri tanısı ile ilk kez başvuran 111 hasta çalışmaya alındı. Hastalar Gastroenteroloji polikliniğine yönlendirildi. Burada İç Hastalıkları uzmanı tarafından hastalar değerlendirildi. Tüm hastalara Roma 3 tanı kriterlerine göre IBS anketi yapıldı. 8 Hastaya IBS tanısı kondu. Bulgular: 111 yeni tanı akciğer kanserli hastada yapılan değerlendirme sonucunda 8 hastada IBS tespit edildi %7,2 . IBS tespit edilen hastaların tamamı erkekti. Hastaların birinde diyare dominant, ikisinde mixt tip ve beşinde konstipasyon dominant tip IBS tespit edildi. IBS tanısı konan 6 hasta yassı hücreli, 1 hasta küçük hücreli, 1 hasta adeno kanserdi. IBS ile Diabetes Mellitus DM , Hipertansiyon HT , Koroner Arter Hastalığı KAH , Kronik Obstrüktif Akciğer Hastalığı KOAH ve alkol kullanımı arasında ilişki saptanmadı p>0,05 . IBS ile yalnızca sigara kullanımı arasında ilişki saptandı p: 0,02 .Sonuç:.Akciğer kanseri IBS için bir risk faktörü kabul edilebilir bunun altındaki temel nedende sigara içiciliğidir

Kaynakça

  • Hu LY, Ku FC, Lu T, Shen CC, Hu YW, Yeh CM et al. Risk of cancer in patients with irritable bowel syndrome: a nationwide population-based study. Ann Epidemiol. 2015 Dec;25(12):924-8.
  • Ruiz-López MC, Coss-Adame E. Quality of life in patients with different constipation subtypes based on the Rome III criteria. Rev Gastroenterol Mex. 2015 Jan-Mar;80(1):13-20.
  • Karaman N, Türkay C, Yönem Ö. Irritable bowel syndrome prevalen- ce in city center of Sivas. Turk j Gastroenterol. 2003;14(2): 128-31.
  • Özden A, Köksal AŞ,Oğuz D, et al.The frequency of irritabl bowel syndrome in primer care centers of Turkey.Akademik Gastroente- roloji Dergisi 2006;5(1):4-15
  • Fujiwara Y, Kubo M, Kohata Y, Machida H, Okazaki H, Yamagami H et al. Cigarette smoking and its association with overlapping gast- roesophageal reflux disease, functional dyspepsia, or irritable bowel syndrome. Intern Med. 2011;50(21):2443-7. Epub 2011 Nov 1.
  • Kerryn W. Reding, Kevin C. Cain, Monica E. Jarrett, Margaret D. Eugenio, and Margaret M. Heitkemper. Relationship between Patterns of Alcohol Consumption and Gastrointestinal Symptoms among Patients with Irritable Bowel Syndrome Am J Gastroente- rol. 2013 February ; 108(2): 270–276
  • Holmes EC,Livingston R. Neoplasms of the thorax. Holand JF, Eds. Cancer Medicine, Philadelphia:Lea and Febiger, 1993; 1285.
  • Pişikpaşa N., Pişikpaşa M.E. Polis Hastalarda Sigara İçme Alış- kanlığı ile İrritabl Barsak Sendromu İlişkisi. Balıkesir Health Sciences Journal. 4(1): 24-26
  • Scott AM, Kellow SE, Shuter B, et al. Effects of cigarette smoking on solid and liquid intragastric distribution and gastrik emptying. Gastroenterology 1993; 104(2):410-6.
  • Biedermann L., Zeitz J., Mwinyi J., Minder ES, Rehman A., Ott S.J.,et al. Smoking Cessation Induces Profound Changes in the Composition of the Intestinal Microbiota in Humans.PLoS ONE, 2013; 8 (3): e59260
  • Yilmaz, Ş., Dursun, M., Ertem, M., Canoruc, F., & Turhanoğlu, A. (2005). The epidemiological aspects of irritable bowel syndrome in Southeastern Anatolia: a stratified randomised community‐ba- sed study. International journal of clinical practice, 59(3), 361-369.
  • Celebi, S., Acik, Y., Deveci, S. E., Bahcecioglu, I. H., Ayar, A., Demir, A., & Durukan, P. (2004). Epidemiological features of irri- table bowel syndrome in a Turkish urban society. Journal of gast- roenterology and hepatology, 19(7), 738-743.
  • Sadik, R., Björnsson, E., & Simrén, M. (2010). The relationship between symptoms, body mass index, gastrointestinal transit and stool frequency in patients with irritable bowel syndrome. Europe- an journal of gastroenterology & hepatology, 22(1), 102-108
  • Schneck, A. S., Anty, R., Tran, A., Hastier, A., Amor, I. B., Gugen- heim, J., ... & Piche, T. (2015). Increased Prevalence of Irritable Bowel Syndrome in a Cohort of French Morbidly Obese Patients Candidate for Bariatric Surgery.Obesity surgery, 1-6.
  • Rajendra S, Alahuddin S. Prevalance of irritable bowel syndrome in a multi-ethnic Asian population. Aliment Pharmacol Ther 2004; 19: 704-6.
  • Thompson WG, Heaton KW, Smyth GT, et al. Irritable bowel syndrome in general practice: prevalance, characteristics, and re- ferral. Gut 2000: 46: 78-82.
  • Hu, L. Y., Ku, F. C., Lu, T., Shen, C. C., Hu, Y. W., Yeh, C. M. et al. Risk of cancer in patients with irritable bowel syndrome: a nationwide population-based study. Annals of epidemiology, 2015 25(12), 924-928..

Prevalence of Irritable Bowel Syndrome in The Patients With Lung Cancer

Yıl 2016, Cilt: 8 Sayı: 1, 36 - 39, 01.03.2016

Öz

Aim:Irritable bowel syndrome IBS is a functional disorder of bowel. Lung cancer is one of the most common types of cancer. The relationship between IBS and smoking is controversial. Smoking is responsible for about 90% of all lung cancer. In this study, we aimed to determine the prevalence of IBS in newly diagnosed lung cancer patients and the association IBS with pathologic subtypes and smoking. Methods: A total of 111 patients with newly diagnosed lung cancer that refered to medical Oncology Clinic of Sakarya University for first time were included the study. Patients were referred to the gastroenterology clinic. The patients were assessed by an internal medicine specialist here. IBS questionnaire based on Roma III criterias were made to all patients and 8 patients diagnosed with IBS.Results: 8 patients diagnosed with IBS 7,2% . after evaluation of 111 patients with newly diagnosed lung cancer. All patients with IBS were men. One of the patients were diagnosed as diarrhea dominant IBS; two of the patients were diagnosed as mixed type IBS and five of the patients were diagnosed as constipation dominant IBS. 6 patients were squamos cell ca, 1 patient was adeno ca and 1 patient was small cell ca. All patients diagnosed as IBS were smoking but the mean smoking duration is lower than the overall group. The relationship was not find between IBS and diabetes mellitus DM , hypertension HT , Coronary Artery Disease CAD , Chronic Obstructive Pulmonary Disease COPD p>0,05 . IBS was associated only with the use of smoking p = 0.02 .Conclusion:. Lung cancer can be considered a risk factor for IBS. Smokins is the main reason under this

Kaynakça

  • Hu LY, Ku FC, Lu T, Shen CC, Hu YW, Yeh CM et al. Risk of cancer in patients with irritable bowel syndrome: a nationwide population-based study. Ann Epidemiol. 2015 Dec;25(12):924-8.
  • Ruiz-López MC, Coss-Adame E. Quality of life in patients with different constipation subtypes based on the Rome III criteria. Rev Gastroenterol Mex. 2015 Jan-Mar;80(1):13-20.
  • Karaman N, Türkay C, Yönem Ö. Irritable bowel syndrome prevalen- ce in city center of Sivas. Turk j Gastroenterol. 2003;14(2): 128-31.
  • Özden A, Köksal AŞ,Oğuz D, et al.The frequency of irritabl bowel syndrome in primer care centers of Turkey.Akademik Gastroente- roloji Dergisi 2006;5(1):4-15
  • Fujiwara Y, Kubo M, Kohata Y, Machida H, Okazaki H, Yamagami H et al. Cigarette smoking and its association with overlapping gast- roesophageal reflux disease, functional dyspepsia, or irritable bowel syndrome. Intern Med. 2011;50(21):2443-7. Epub 2011 Nov 1.
  • Kerryn W. Reding, Kevin C. Cain, Monica E. Jarrett, Margaret D. Eugenio, and Margaret M. Heitkemper. Relationship between Patterns of Alcohol Consumption and Gastrointestinal Symptoms among Patients with Irritable Bowel Syndrome Am J Gastroente- rol. 2013 February ; 108(2): 270–276
  • Holmes EC,Livingston R. Neoplasms of the thorax. Holand JF, Eds. Cancer Medicine, Philadelphia:Lea and Febiger, 1993; 1285.
  • Pişikpaşa N., Pişikpaşa M.E. Polis Hastalarda Sigara İçme Alış- kanlığı ile İrritabl Barsak Sendromu İlişkisi. Balıkesir Health Sciences Journal. 4(1): 24-26
  • Scott AM, Kellow SE, Shuter B, et al. Effects of cigarette smoking on solid and liquid intragastric distribution and gastrik emptying. Gastroenterology 1993; 104(2):410-6.
  • Biedermann L., Zeitz J., Mwinyi J., Minder ES, Rehman A., Ott S.J.,et al. Smoking Cessation Induces Profound Changes in the Composition of the Intestinal Microbiota in Humans.PLoS ONE, 2013; 8 (3): e59260
  • Yilmaz, Ş., Dursun, M., Ertem, M., Canoruc, F., & Turhanoğlu, A. (2005). The epidemiological aspects of irritable bowel syndrome in Southeastern Anatolia: a stratified randomised community‐ba- sed study. International journal of clinical practice, 59(3), 361-369.
  • Celebi, S., Acik, Y., Deveci, S. E., Bahcecioglu, I. H., Ayar, A., Demir, A., & Durukan, P. (2004). Epidemiological features of irri- table bowel syndrome in a Turkish urban society. Journal of gast- roenterology and hepatology, 19(7), 738-743.
  • Sadik, R., Björnsson, E., & Simrén, M. (2010). The relationship between symptoms, body mass index, gastrointestinal transit and stool frequency in patients with irritable bowel syndrome. Europe- an journal of gastroenterology & hepatology, 22(1), 102-108
  • Schneck, A. S., Anty, R., Tran, A., Hastier, A., Amor, I. B., Gugen- heim, J., ... & Piche, T. (2015). Increased Prevalence of Irritable Bowel Syndrome in a Cohort of French Morbidly Obese Patients Candidate for Bariatric Surgery.Obesity surgery, 1-6.
  • Rajendra S, Alahuddin S. Prevalance of irritable bowel syndrome in a multi-ethnic Asian population. Aliment Pharmacol Ther 2004; 19: 704-6.
  • Thompson WG, Heaton KW, Smyth GT, et al. Irritable bowel syndrome in general practice: prevalance, characteristics, and re- ferral. Gut 2000: 46: 78-82.
  • Hu, L. Y., Ku, F. C., Lu, T., Shen, C. C., Hu, Y. W., Yeh, C. M. et al. Risk of cancer in patients with irritable bowel syndrome: a nationwide population-based study. Annals of epidemiology, 2015 25(12), 924-928..
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Research Article
Yazarlar

Ceyhun Varım Bu kişi benim

Tezcan Kaya Bu kişi benim

İbrahim Vedat Bayoğlu Bu kişi benim

Cengiz Karacaer Bu kişi benim

Ahmet Nalbant Bu kişi benim

Mustafa Altınbaş Bu kişi benim

Ali Tamer Bu kişi benim

Yayımlanma Tarihi 1 Mart 2016
Yayımlandığı Sayı Yıl 2016 Cilt: 8 Sayı: 1

Kaynak Göster

Vancouver Varım C, Kaya T, Bayoğlu İV, Karacaer C, Nalbant A, Altınbaş M, Tamer A. Akciğer Kanseri Tanılı Hastalarda İrritable Barsak Sendromu Sıklığı. otd. 2016;8(1):36-9.

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