A Case of Primary Breast Angiosarcoma in a Male Patient with Literature Review

Öz

Primary breast angiosarcomas are rare malignities of breast. They are extremely rare in male patients. Breast angiosarcomas can occur as primary or secondary angiosarcomas. In angiosarcomas, clinicopathological factors such as tumour size, surgical margin status have been reported to be important in prognosis. In this article, breast angiosarcoma in a male patient will be presented in the light of the literature.

Anahtar Kelimeler

• anjiosarcom
• breast
• male

Erkek bir Hastada Literatür Taraması ile Birlikte Primer Meme Anjiosarkom Olgusu Sunumu

Öz

Primer meme anjiosarkomları memenin nadir görülen maligniteleridir. Erkek hastalarda son derece nadir görülür. Meme anjiosarkomları primer ve sekonder anjiosarkomlar olarak ortaya çıkabilir. Anjiosarkomlarda tümör boyutu, cerrahi sınır durumu gibi klinikopatolojik faktörlerin prognozda önemli olduğu rapor edilmiştir. Bu makalede erkek bir hastada görülen meme anjiosarkomu literatür verileri ışığında sunulacaktır.

Anahtar Kelimeler

• anjiosarkom
• meme
• erkek

Kaynakça

1. 1. Adem C, Reynolds C, Ingle JN, et al. Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature. Br J Cancer. 2004; 91(2):237-41.
2. 2. Tavassoli FA. Tavassoli FA. Vascular lesions. İn: Tavassoli FA. Pathology of the Breast 2nd ed. Hong Kong, China: Appleton and Lange; 1999: 633-673. 1999. 633-673 s.
3. 3. Rosen PP, Kimmel M, Ernsberger D. Mammary angiosarcoma: the prognostic significance of tumor differentiation. Cancer. 1988; 62(10):2145-51.
4. 4. Glazebrook KN, Magut MJ, Reynolds C. Angiosarcoma of the breast. Am J Roentgenol. 2008;190(2):533-8.
5. 5. Nascimento AF, Raut CP, Fletcher CD. Primary angiosarcoma of the breast: clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic. Am J Surg Pathol. 2008;32(12):1896-904.
6. 6. Granier G, Lemoine MC, Mares P, et al. Primary angiosarcoma of the male breast. İçinde: Annales de Pathologie. 2005. s. 235-9.
7. 7. Wang ZS, Zhan N, Xiong CL, et al. Primary epithelioid angiosarcoma of the male breast: report of a case. Surg Today. 2007;37:782-6.
8. 8. Rosen PP, Hoda SA, Brogi E, et al. Rosen’S Breast Pathology. 4th. Philadelphia, Pa, USA: Lippincott Williams & Wilkins; 2014.

9. 9. Mansouri H, Jalil A, Chouhou L, et al. A rare case of angiosarcoma of the breast in a man: case report. Eur J Gynaecol Oncol. 2000;21(6):603-4.
10. 10. Kamat L, Rosa M, Weinfurtner R, et al. Primary breast angiosarcoma in a male. Breast J. 2015;21(5):545-8.
11. 11. Da Silva BB, Eulálio Filho WMN, Costa PVL, et al. A rare case of primary breast angiosarcoma in a male: a case report. BMC Cancer. 16.10.2018;18(1):978.
12. 12. By Awan LB, Bhandarkar G, Kim J. et al. Primary mammary angiosarcoma in a male. Applied Radiology https :// applied.radiology.com/articles/primary-mammary- angiosarcoma-in-a-male. access 13.07. 2023.
13. 13. Bousquet, G., Confavreux, C., Magné, N. Et al. Outcome and prognostic factors in breast sarcoma: a multicenter study from the rare cancer network. Radiotherapy and Oncology, 2007 85(3), 355-361.
14. 14. Shet, T., Malaviya, A., Nadkarni, M., et al. Primary angiosarcoma of the breast: observations in Asian Indian women. Journal of surgical oncology.2006; 94(5): 368-374.
15. 15. Koerner F. Sarcoma. In: Hoda S, Brogi E, Koerner F, Rosen PP, eds. Rosen’s Breast Pathology, 4th edn. Philadelphia, PA: LWW, Wolters Klumer, 2014. 1118-26 s.
16. 16. Branton PA, Lininger R, Tavassoli FA. Papillary endothelial hyperplasia of the breast: the great impostor for angiosarcoma: a clinicopathologic review of 17 cases. Int J Surg Pathol. 2003;11(2):83-7.
17. 17. Wagner, M. J., Othus, M., Patel, et al. Multicenter phase II trial (SWOG S1609, cohort 51) of ipilimumab and nivolumab in metastatic or unresectable angiosarcoma: a substudy of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART). Journal for immunotherapy of cancer, 2021; 9(8).
18. 18. Van Der Graaf, W. T., Blay, J. Y., et al Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet, 2012; 379(9829), 1879-1886.
19. 19. Jones, R. L., Ravi, V., Brohl, A. S., Chawla, S.,et al. Efficacy and safety of TRC105 plus pazopanib vs pazopanib alone for treatment of patients with advanced angiosarcoma: A randomized clinical trial. JAMA oncology, 2022; 8(5), 740-747.
20. 20. Maki, R. G., D'Adamo, D. R., Keohan, et al . Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. Journal of Clinical Oncology, 2009; 27(19): 3133.
21. 21. George, S., Merriam, P., Maki, R. G., et al. Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas. Journal of Clinical Oncology, 2009; 27(19): 3154.