Comparison of Serum Nesfatin-1 and Visfatin Levels Between Patients with Rheumatoid Arthritis and Healthy Controls

Öz

Even though elevated nesfatin-1 levels were reported in patients with rheumatoid arthritis (RA) previously, the possible role of body mass index (BMI) was not excluded. The aim of the present study was to compare serum nesfatin-1 and visfatin levels between patients with RA and healthy controls who have normal BMI values (18.50.05). It seems that nesfatin-1 levels are significantly higher in RA patients compared to healthy peers. However, nesfatin-1 levels were not found related to disease activity.

Anahtar Kelimeler

• Adipokines
• arthritis
• body mass index

Romatoid Artritli Hastalar ile Sağlıklı Kontroller Arasında Serum Nesfatin-1 ve Visfatin Düzeylerinin Karşılaştırılması

Öz

Romatoid artritli (RA) hastalarda nesfatin-1 düzeylerinin yükseldiği daha önce bildirilmiş olmasına rağmen vücut kütle indeksinin (BMI) olası rolü dışlanmamıştır. Bu çalışmanın amacı BMI değerleri normal (18,50,05). RA hastalarında nesfatin-1 düzeylerinin sağlıklı yaşıtlarına göre anlamlı derecede yüksek olduğu görülmektedir. Ancak nesfatin-1 düzeylerinin hastalık aktivitesiyle ilişkisi saptanamadı.

Anahtar Kelimeler

• Adipokinler
• artrit
• vücut kütle indeksi

Kaynakça

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