The Evaluation of Benign Prostate Hyperplasia and Chronic Prostatitis Symptoms with Obstructive Sleep Apnea Syndrome Patients

Öz

Obstructive Sleep Apnea Syndrome (OSAS) is a chronic disorder that increases in prevalence with increasing age. Oxidative stress (OS) and inflammation resulting from OSAS are responsible for the etiopathogenesis of many diseases. OS and inflammation have been found to play a role in the etiopathogenesis of benign prostate hyperplasia (BPH) and chronic prostatitis (CP). The present study aims to compare the prevalence of BPH and CP between patients diagnosed with OSAS and non-OSAS volunteers. Included in the study were 102 patients with OSAS and 110 non-OSAS volunteers, all of whom were assessed with the Berlin Questionnaire, the Epworth Sleepiness Scale, the International Prostate Symptom Score (IPSS) and the Chronic Prostatitis Symptom Index (CPSI). No significant difference was found in the age (p=0.267) and body mass index (BMI) (p=0.995) values of the OSAS patients and non-OSAS volunteers. Berlin Questionnaire (p<0.001) and Epworth Sleepiness Scale (p<0.001) positivity was more common among the OSAS patients than in the control group. The IPSS (p<0.001), CPSI pain score (p<0.001) and CPSI urination symptoms (p=0.002) values were higher in the OSAS patients than in the controls. OSAS patients had more BPH and CP symptoms than the controls. The effective treatment of OSAS is important for the prevention of such chronic diseases as BPH and CP that may develop at later stages of life and that can impair the quality of life of the patient.

Anahtar Kelimeler

• Obstructive Sleep Apnea Syndrome
• Chronic Prostatitis
• Benign Prostate Hyperplasia

Obstrüktif Uyku Apne Sendromlu Hastalarda Benign Prostat Hiperplazisi ve Kronik Prostatit Semptomlarının Değerlendirilmesi

Öz

Obstrüktif uyku apnesi sendromu (OSAS), yaşla birlikte görülme sıklığı artan kronik bir hastalıktır. OSAS sonucu meydana gelen oksidatif stres (OS) ve inflamasyon, birçok hastalığın etyopatogenezinden sorumlu tutulmaktadır. OS ve inflamasyon, benign prostat hiperplazisi (BPH) ve kronik prostatit (CP) etyopatogenezinde yer almaktadır. Çalışmamız OSAS tanılı hastalarda BPH ve CP görülme sıklığının OSAS olmayanlarla karşılaştırılmasını amaçlamaktadır. Çalışmaya 102 OSAS tanılı hasta ve 110 OSAS olmayan gönüllü dahil edildi. Katılımcılara Berlin Anketi, Epworth Uykululuk Anketi, Interantional Prostate Symtom Score (IPSS) ve Chronic Prostatitis Symptom Index (CPSI) anketi uygulandı. OSAS ve OSAS olmayanlar arasında yaş (p=0.267), vücut kitle indeksi(BMI)(p=0.995) açısından farklılık olmadığı görüldü. OSAS grubunda, kontrol grubuna kıyasla Berlin Anketi (p<0.001) ve Epworth Uykululuk Ölçeği (p<0.001) pozitifliğinin daha fazla olduğu görüldü. OSAS grubunda, kontrol grubuna göre IPSS (p<0.001), CPSI ağrı skoru (p<0.001) ve CPSI işeme semptomları (p=0.002) değerlerinin daha yüksek olduğu görüldü. OSAS’lı hastalarda kontrol grubuna göre BPH ve CP semptomlarının daha fazla olduğu gözlendi. OSAS’ın etkin şekilde tedavi edilmesi ilerleyen dönemlerde hastalarda gelişebilecek BPH ve CP gibi yaşam kalitesini olumsuz etkileyen kronik hastalıkların önlenmesi açısından önem arz etmektedir.

Anahtar Kelimeler

• Obstrüktif Uyku Apne Sendromu
• Kronik Prostatit
• Benign Prostat Hiperplazisi

Kaynakça

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