Balloon Cervical Catheter for Second-Trimester Pregnancy Termination: A Single-Center Retrospective Study

Bu makalenin ilk hali 11 Şubat 2026 tarihinde yayımlandı. https://dergipark.org.tr/tr/pub/otd/article/1791896

Öz

To compare the effectiveness and safety of vaginal misoprostol alone versus misoprostol combined with a double-balloon catheter (DBC) for pregnancy termination at 12–22 weeks. Methods: Retrospective review of cases with perinatology board approval between January–September 2019. Primary outcome was induction‑to‑abortion interval; secondary outcomes were completion within 24 hours, bleeding (1 pad=40 mL), and complications. Results: Of 75 cases, 25 were excluded; 50 were analyzed (25/25). Induction‑to‑abortion interval was shorter with misoprostol (14.5 h [IQR 8.8–17.8]) than with misoprostol+DBC (24.3 h [17.2–45.5]) (p=0.0015). Completion ≤24 h: 92.0% vs 48.0% (p=0.0015; OR=0.08; 95% CI 0.02–0.42). Median bleeding was similar (20 mL vs 20 mL; p=0.944). Complications were rare and comparable in both groups (uterine rupture, post‑procedure curettage, transfusion: n=1 each per group). Conclusion: Misoprostol alone was associated with shorter time‑to‑abortion and higher 24‑hour completion without increased bleeding; adding a DBC did not provide a time advantage.

Anahtar Kelimeler

• misoprostol
• double balloon catheter
• second trimester
• pregnancy termination
• induction

İkinci Trimester Gebelik Terminasyonunda Vajinal Misoprostol ile Misoprostol+Çift Balon Servikal Kateter Kombinasyonunun Karşılaştırılması: Tek Merkezli Retrospektif Çalışma

Bu makalenin ilk hali 11 Şubat 2026 tarihinde yayımlandı. https://dergipark.org.tr/tr/pub/otd/article/1791896

Düzeltme Notu

Destek ve Teşekkür Beyanı: Çalışmamız Eskişehir Osmangazi Üniversitesi Bilimsel Araştırma Projeleri Birimi tarafından desteklenmiştir. Proje kodu: 201911A214.

Öz

12–22. gebelik haftalarında terminasyon uygulanan olgularda, yalnız misoprostol ile misoprostol+çift balon kateter (ÇBK) protokollerinin etkinlik ve güvenliğini karşılaştırmak. Gereç ve Yöntem: Ocak–Eylül 2019 arasında tek merkezde yürütülen retrospektif kohortta olgular iki kola ayrıldı: yalnız misoprostol ve misoprostol+ÇBK. Birincil sonlanım indüksiyon‑abortus süresi (saat), ikincil sonlanımlar ilk 24 saatte terminasyon, kanama (40 mL/ped) ve komplikasyonlardı. Bulgular: Toplam 75 olgunun 25’i dışlama ölçütleri nedeniyle çıkarıldı; 50 olgu analize dâhil edildi (misoprostol n=25; misoprostol+ÇBK n=25). İndüksiyon‑abortus süresi medyanı misoprostolde 14,5 saat [ÇAA 8,8–17,8], misoprostol+ÇBK’de 24,3 saat [17,2–45,5] idi (p=0,0015). İlk 24 saatte terminasyon, misoprostolde %92,0 (23/25), misoprostol+ÇBK’de %48,0 (12/25) bulundu (p=0,0015; OR=0,08; %95 GA 0,02–0,42). Kanama medyanı her iki kolda 20 mL idi (p=0,944). Komplikasyonlar her iki kolda nadirdi (uterin rüptür, küretaj, transfüzyon: her kolda n=1). Sonuç: Yalnız misoprostol, ÇBK eklenmesine göre daha kısa süre ve daha yüksek 24 saat içinde tamamlama ile ilişkilidir; kanama benzer görünmektedir.

Anahtar Kelimeler

• misoprostol
• çift balon kateter
• ikinci trimester
• gebelik termiansyonu
• indüksiyon

Kaynakça

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