Araştırma Makalesi

Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8

Cilt: 48 Sayı: 6 22 Eylül 2026
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Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8

Öz

Patients increasingly consult conversational artificial intelligence about hand and wrist conditions, but the performance of proprietary large language models remains unclear. We compared the reliability, overall quality, and readability of patient-facing texts generated by GPT-5.5 and Claude Opus 4.8. Thirty hand surgery topics were selected from orthopedic education resources and the authors' outpatient practice. Each model received the same prompt and generated one response per topic (60 texts). Two fellowship-trained, certified hand surgeons independently evaluated source-masked outputs. DISCERN assessed reliability and treatment information, the Global Quality Score (GQS) overall quality, and the Flesch-Kincaid Grade Level (FKGL) and Flesch Reading Ease (FRE) readability. Platforms were compared with the Mann-Whitney U test and interrater agreement with the intraclass correlation coefficient (ICC). Median DISCERN scores were 66.5 for GPT-5.5 and 63.5 for Claude Opus 4.8 (p = 0.143); median GQS was 4.0 for both (p = 0.389). Claude Opus 4.8 had a lower median FKGL (8.75 vs 10.4; p < 0.001) and higher median FRE (50.35 vs 43.6; p = 0.009). ICCs (95% CIs) were 0.755 (0.589-0.853) for DISCERN and 0.676 (0.458-0.807) for GQS. Expert-rated reliability and overall quality did not differ significantly, whereas Claude Opus 4.8 produced more favorable formula-based readability scores; median FKGL for both models nevertheless remained above the recommended sixth-grade level. Because FKGL and FRE quantify surface linguistic complexity rather than understanding, these findings describe written outputs only; they do not establish better patient comprehension, clinical effectiveness, factual equivalence, or safety.

Anahtar Kelimeler

Destekleyen Kurum

The authors declared that this study received no financial support.

Proje Numarası

Yok

Etik Beyan

This study did not involve human participants, patient data, identifiable personal information, biological materials, animals, or any diagnostic or therapeutic intervention. Therefore, ethics committee approval and informed consent were not required. The study was conducted in accordance with research and publication ethics.

Teşekkür

None.

Kaynakça

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  2. 2. Daraz L, Morrow AS, Ponce OJ, et al. Readability of online health information: a meta-narrative systematic review. Am J Med Qual 2018;33(5):487-492.
  3. 3. Aydin S, Karabacak M, Vlachos V, Margetis K. Large language models in patient education: a scoping review of applications in medicine. Front Med (Lausanne) 2024;11:1477898.
  4. 4. Jagiella-Lodise O, Suh N, Zelenski NA. Can patients rely on ChatGPT to answer hand pathology-related medical questions? Hand (N Y) 2025;20(5):801-809.
  5. 5. Croen BJ, Abdullah MS, Berns E, et al. Evaluation of patient education materials from large-language artificial intelligence models on carpal tunnel release. Hand (N Y) 2025;20(6):893-899.
  6. 6. Parmar RP, Daulat SR, Shah R, Brady TT, Montague M, Roth C. Readability, accuracy, and lexical diversity of new ChatGPT models for common carpal tunnel syndrome questions. Hand (N Y). Published online February 8, 2026.
  7. 7. Pohl NB, Derector E, Rivlin M, et al. A quality and readability comparison of artificial intelligence and popular health website education materials for common hand surgery procedures. Hand Surg Rehabil 2024;43(3):101723.
  8. 8. Gorgos P, Ternell KH, Hammarstrand C, et al. ChatGPT and Claude in hand surgery: an explanatory evaluation of clinical decision support on common surgical cases. Hand Surg Rehabil 2025;44(6):102530.

Ayrıntılar

Birincil Dil

İngilizce

Konular

El Cerrahisi

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

22 Eylül 2026

Gönderilme Tarihi

28 Temmuz 2026

Kabul Tarihi

14 Ağustos 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 48 Sayı: 6

Kaynak Göster

APA
Adıgüzel, İ. F., & Ertem, H. (2026). Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8. Osmangazi Tıp Dergisi, 48(6), 1072-1078. https://doi.org/10.20515/otd.2004895
AMA
1.Adıgüzel İF, Ertem H. Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8. Osmangazi Tıp Dergisi. 2026;48(6):1072-1078. doi:10.20515/otd.2004895
Chicago
Adıgüzel, İbrahim Faruk, ve Hakan Ertem. 2026. “Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8”. Osmangazi Tıp Dergisi 48 (6): 1072-78. https://doi.org/10.20515/otd.2004895.
EndNote
Adıgüzel İF, Ertem H (01 Eylül 2026) Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8. Osmangazi Tıp Dergisi 48 6 1072–1078.
IEEE
[1]İ. F. Adıgüzel ve H. Ertem, “Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8”, Osmangazi Tıp Dergisi, c. 48, sy 6, ss. 1072–1078, Eyl. 2026, doi: 10.20515/otd.2004895.
ISNAD
Adıgüzel, İbrahim Faruk - Ertem, Hakan. “Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8”. Osmangazi Tıp Dergisi 48/6 (01 Eylül 2026): 1072-1078. https://doi.org/10.20515/otd.2004895.
JAMA
1.Adıgüzel İF, Ertem H. Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8. Osmangazi Tıp Dergisi. 2026;48:1072–1078.
MLA
Adıgüzel, İbrahim Faruk, ve Hakan Ertem. “Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8”. Osmangazi Tıp Dergisi, c. 48, sy 6, Eylül 2026, ss. 1072-8, doi:10.20515/otd.2004895.
Vancouver
1.İbrahim Faruk Adıgüzel, Hakan Ertem. Patient Education in Hand Surgery: A Blinded Comparison of GPT-5.5 and Claude Opus 4.8. Osmangazi Tıp Dergisi. 01 Eylül 2026;48(6):1072-8. doi:10.20515/otd.2004895


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