Olgu Sunumu
BibTex RIS Kaynak Göster

Squamous Cell Carcinoma Associated with İll-Fitting Denture: A Case Report

Yıl 2020, , 158 - 162, 28.09.2020
https://doi.org/10.20515/otd.771972

Öz

Oral squamous cell carcinoma (OSCC) is the most common histopathologic type of oral cancer in adults. It is related to risk factors such as smoking and alcohol consumption. The issue of the chronic irritation of ill-fitting dentures playing a role in etiology is controversial. It occurs mostly in male individuals over 40 years of age. The most common sites for OSCC in oral cavity are the tongue and floor of mouth, while gingiva and buccal mucosa are less frequently involved. Prognosis is usually fair when OSCC is diagnosed early. A 70-year-old male patient presented to our clinic with a complaint of pain in the floor of the mouth due to an ill-fitting denture. Intraoral examination revealed an ulcerated, exophytic soft tissue growth on the floor of the mouth. The initial diagnosis of OSCC was considered based on the clinical features of the lesion and anamnesis of the patient. Histopathologic examination confirmed the diagnosis of OSCC. Dentists should be cautious, especially in elderly patients who use dentures because of the high risk of having oral cancers. Clinically, OSCC may be confused with denture-related traumatic ulcers, as it can often occur in the form of painless ulcer. Since early diagnosis is very important, lesions that do not heal within two weeks should be evaluated for malignancy.

Kaynakça

  • TC Sağlık Bakanlığı Kanserle Savaş Dairesi Başkanlığı, TS. Kanserle savaş politikası ve kanser verileri (1995-1999). Ankara:Bakanlık Yayın; 2002.
  • Boring CC, Squires TS, Tong T, Montgomery S. Cancer statistics, 1994. CA Cancer J Clin. 1994;44(1):7-26.
  • Howell RE, Wright BA, Dewar R. Trends in the incidence of oral cancer in Nova Scotia from 1983 to 1997. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(2):205-12.
  • Kumar M, Nanavati R, Modi TG, Dobariya C. Oral cancer: Etiology and risk factors: A review. J Cancer Res Ther. 2016;12(2):458.
  • Kayhan KB, Meral Ü. Oral cavity cancers and classification. Eur. Oral Res. 2011;45(1):55.
  • Cawson RA, Odell EW, Porter SR.Cawson’s essentialsoral pathology and oral medicine. 7thEd. Edinburgh: Churchill Livingstone; 2002.
  • Akkaya N, Yandımata Çokaktaş Z, editor. Oral radyoloji ilkeler ve yorumlama. Ankara: Palme Yayınevi; 2018.
  • Lam L, Logan RM, Luke C. Epidemiological analysis of tongue cancer in South Australia for the 24‐year period, 1977–2001. Aust dent j. 2006;51(1):16-22.
  • Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for oral cancer in newly diagnosed patients aged 45 years and younger: a case-control study in Southern England.J Oral Pathol Med. 2004;33(9):525-32.
  • McDowell JD. An overview of epidemiology and common risk factors for oral squamous cell carcinoma. Otolaryngol Clin North Am. 2006;39(2):277-94.
  • Özateş Z, Koç N, Ölmez D, Altun S, Doğan ÖB, İriağaç Ş. Oral skuamoz hücreli karsinoma: 5 olgu sunumu. Selcuk Dent J.6(4):112-8.
  • Gillison ML. Current topics in the epidemiology of oral cavity and oropharyngeal cancers. head & neck: Head neck-j sci spec.2007;29(8):779-92.
  • Manoharan S, Nagaraja V, Eslick GD. Ill-fitting dentures and oral cancer: a meta-analysis. Oral oncol. 2014;50(11):1058-61.
  • Marshall JR, Graham S, Haughey BP, Shedd D, O'Shea R, Brasure J, et al. Smoking, alcohol, dentition and diet in the epidemiology of oral cancer. Eur J Cancer B Oral Oncol. 1992;28(1):9-15.
  • Velly A, Franco E, Schlecht N, Pintos J, Kowalski LP, Oliveira BVd, et al. Relationship between dental factors and risk of upper aerodigestive tract cancer. Oral oncol. 1998;34(4):284-91.
  • Jainkittivong A, Aneksuk V, Langlais RP. Oral mucosal lesions in denture wearers. Gerodontology. 2010;27(1):26-32.
  • Akçiçek G, Akkaya N, Doğru HB. Hareketli protez kullanımına bağlı gelişen oral mukoza lezyonları: tanımlayıcı klinik araştırma. Acta Odontol Turc. 2017;34(2).
  • Patton LL, Agans R, Elter JR, Southerland JH, Strauss RP, Kalsbeek WD. Oral cancer knowledge and examination experiences among North Carolina adults. J Public Health Dent. 2004;64(3):173-80.
  • Scala M, Moresco L, Comandini D, Monteghirfo S, Tomei D. The role of the general practitioner and dentist in the early diagnosis of preneoplastic and neoplastic lesions of the oral cavity. Minerva stomatol. 1997;46(3):133-7.
  • Türker M, Yücetaş Ş. Ağız, diş, çene hastalıkları ve cerrahisi. Ankara: Atlas Kitapçılık;1997.
  • Scott S, Grunfeld E, Main J, McGurk M. Patient delay in oral cancer: a qualitative study of patients' experiences. Psycho‐Oncology: Journal of the Psychological, Social and Behavioral Dimensions of Cancer. 2006;15(6):474-85.
  • Lee DJ, Saponaro PC. Management of edentulous patients. Dent Clin North Am. 2019;63(2):249-61.
  • Marshall TA, Warren JJ, Hand JS, Xie X-J, Stumbo PJ. Oral health, nutrient intake and dietary quality in the very old. J Am Dent Assoc. 2002;133(10):1369-79.
  • Rotundo LDB, Toporcov TN, Biazevic GH, Carvalho MBd, Kowalski LP, Antunes JLF. Are recurrent denture-related sores associated with the risk of oral cancer? A case control study. Revista brasileira de epidemiologia. 2013;16:705-15.
  • Ogden GR. Alcohol and oral cancer. Alcohol. 2005;35(3):169-73.

Uyumsuz Protezle İlişkili Skuamöz Hücreli Karsinom: Olgu Sunumu

Yıl 2020, , 158 - 162, 28.09.2020
https://doi.org/10.20515/otd.771972

Öz

Oral skuamöz hücreli karsinom (OSHK) yetişkinlerde oral kanserlerin en sık görülen histopatolojik tipidir. Sigara ve alkol tüketimi gibi risk faktörleri ile ilişkilidir. Doku uyumu bozuk protezlerin oluşturduğu kronik irritasyonun, etiyolojide rol oynayıp oynamadığı konusu tartışmalıdır. Çoğunlukla 40 yaşın üzerindeki erkek bireylerde görülür. Ağız boşluğunda OSHK’nin en sık görüldüğü bölgeler, dil ve ağız tabanıdır, dişeti ve bukkal mukozada daha az sıklıkta etkilenir. OSHK erken teşhis edildiğinde, prognozu oldukça iyidir. 70 yaşında erkek hasta, uyumsuz protezinin sebep olduğu ağız tabanındaki ağrı şikayeti ile kliniğimize başvurdu. İntraoral muayenede ağız tabanında ülsere, ekzofitik yumuşak doku büyümesi saptandı. Lezyonun klinik özellikleri ve hastanın öyküsüne dayanarak ön tanıda OSHK düşünüldü. Histopatolojik inceleme OSHK tanısını doğruladı. Diş hekimleri, özellikle protez kullanan yaşlı hastalarda ağız kanserlerinin görülme riskinin yüksek olması nedeniyle dikkatli olmalıdır. Klinik olarak OSHK, sıklıkla ağrısız ülser şeklinde görülebileceğinden, proteze bağlı travmatik ülserlerle karıştırılabilir. Erken teşhis çok önemli olduğu için iki hafta içinde iyileşmeyen lezyonlar malignite yönünden değerlendirilmelidir.

Kaynakça

  • TC Sağlık Bakanlığı Kanserle Savaş Dairesi Başkanlığı, TS. Kanserle savaş politikası ve kanser verileri (1995-1999). Ankara:Bakanlık Yayın; 2002.
  • Boring CC, Squires TS, Tong T, Montgomery S. Cancer statistics, 1994. CA Cancer J Clin. 1994;44(1):7-26.
  • Howell RE, Wright BA, Dewar R. Trends in the incidence of oral cancer in Nova Scotia from 1983 to 1997. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(2):205-12.
  • Kumar M, Nanavati R, Modi TG, Dobariya C. Oral cancer: Etiology and risk factors: A review. J Cancer Res Ther. 2016;12(2):458.
  • Kayhan KB, Meral Ü. Oral cavity cancers and classification. Eur. Oral Res. 2011;45(1):55.
  • Cawson RA, Odell EW, Porter SR.Cawson’s essentialsoral pathology and oral medicine. 7thEd. Edinburgh: Churchill Livingstone; 2002.
  • Akkaya N, Yandımata Çokaktaş Z, editor. Oral radyoloji ilkeler ve yorumlama. Ankara: Palme Yayınevi; 2018.
  • Lam L, Logan RM, Luke C. Epidemiological analysis of tongue cancer in South Australia for the 24‐year period, 1977–2001. Aust dent j. 2006;51(1):16-22.
  • Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for oral cancer in newly diagnosed patients aged 45 years and younger: a case-control study in Southern England.J Oral Pathol Med. 2004;33(9):525-32.
  • McDowell JD. An overview of epidemiology and common risk factors for oral squamous cell carcinoma. Otolaryngol Clin North Am. 2006;39(2):277-94.
  • Özateş Z, Koç N, Ölmez D, Altun S, Doğan ÖB, İriağaç Ş. Oral skuamoz hücreli karsinoma: 5 olgu sunumu. Selcuk Dent J.6(4):112-8.
  • Gillison ML. Current topics in the epidemiology of oral cavity and oropharyngeal cancers. head & neck: Head neck-j sci spec.2007;29(8):779-92.
  • Manoharan S, Nagaraja V, Eslick GD. Ill-fitting dentures and oral cancer: a meta-analysis. Oral oncol. 2014;50(11):1058-61.
  • Marshall JR, Graham S, Haughey BP, Shedd D, O'Shea R, Brasure J, et al. Smoking, alcohol, dentition and diet in the epidemiology of oral cancer. Eur J Cancer B Oral Oncol. 1992;28(1):9-15.
  • Velly A, Franco E, Schlecht N, Pintos J, Kowalski LP, Oliveira BVd, et al. Relationship between dental factors and risk of upper aerodigestive tract cancer. Oral oncol. 1998;34(4):284-91.
  • Jainkittivong A, Aneksuk V, Langlais RP. Oral mucosal lesions in denture wearers. Gerodontology. 2010;27(1):26-32.
  • Akçiçek G, Akkaya N, Doğru HB. Hareketli protez kullanımına bağlı gelişen oral mukoza lezyonları: tanımlayıcı klinik araştırma. Acta Odontol Turc. 2017;34(2).
  • Patton LL, Agans R, Elter JR, Southerland JH, Strauss RP, Kalsbeek WD. Oral cancer knowledge and examination experiences among North Carolina adults. J Public Health Dent. 2004;64(3):173-80.
  • Scala M, Moresco L, Comandini D, Monteghirfo S, Tomei D. The role of the general practitioner and dentist in the early diagnosis of preneoplastic and neoplastic lesions of the oral cavity. Minerva stomatol. 1997;46(3):133-7.
  • Türker M, Yücetaş Ş. Ağız, diş, çene hastalıkları ve cerrahisi. Ankara: Atlas Kitapçılık;1997.
  • Scott S, Grunfeld E, Main J, McGurk M. Patient delay in oral cancer: a qualitative study of patients' experiences. Psycho‐Oncology: Journal of the Psychological, Social and Behavioral Dimensions of Cancer. 2006;15(6):474-85.
  • Lee DJ, Saponaro PC. Management of edentulous patients. Dent Clin North Am. 2019;63(2):249-61.
  • Marshall TA, Warren JJ, Hand JS, Xie X-J, Stumbo PJ. Oral health, nutrient intake and dietary quality in the very old. J Am Dent Assoc. 2002;133(10):1369-79.
  • Rotundo LDB, Toporcov TN, Biazevic GH, Carvalho MBd, Kowalski LP, Antunes JLF. Are recurrent denture-related sores associated with the risk of oral cancer? A case control study. Revista brasileira de epidemiologia. 2013;16:705-15.
  • Ogden GR. Alcohol and oral cancer. Alcohol. 2005;35(3):169-73.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm OLGU SUNUMLARI / CASE REPORTS
Yazarlar

Özlem Büşra Doğan 0000-0001-5510-549X

Şeyda İriağaç Bu kişi benim 0000-0001-7827-7446

Hatice Boyacıoğlu Bu kişi benim 0000-0001-7654-5988

Yayımlanma Tarihi 28 Eylül 2020
Yayımlandığı Sayı Yıl 2020

Kaynak Göster

Vancouver Doğan ÖB, İriağaç Ş, Boyacıoğlu H. Uyumsuz Protezle İlişkili Skuamöz Hücreli Karsinom: Olgu Sunumu. Osmangazi Tıp Dergisi. 2020;42(5):158-62.


13299        13308       13306       13305    13307  1330126978