Tip 1 Diyabetes Mellitus Tanılı Pediatrik Nekrobiyozis Lipoidika Olgusu

Öz

Nekrobiyozis lipoidika, etyolojisi ve patogenezi henüz net olarak bilinmeyen granülomatöz bir deri hastalığıdır. Diyabetes mellitus ve nekrobiyozis lipoidika komorbiditesi literatürde sıkça tartışılmakta olup mikroanjiyopatinin bu komorbiditede önemli bir role sahip olduğu düşünülmektedir. Nekrobiyozis lipoidika, diyabetes mellitus ile eş zamanlı ortaya çıkabilmekle beraber diyabetes mellitus tanısından önce veya sonra da ortaya çıkabilmektedir. Nekrobiyozis lipoidikanın kanıtlanmış etkin bir tedavisi bulunmamaktadır. Köbnerizasyon nedeniyle cerrahi tedavi önerilmemektedir. Burada yaklaşık 2 yıldır her iki alt ekstremitede multiple lezyonları olan ve yapılan punch biyopsi ile histopatolojik olarak nekrobiyozis lipoidika tanısı konulan 15 yaşında kız hasta sunuldu. Olgumuz ile nekrobiyozis lipoidika etyolojisi, kliniği ve tedavisi literatür ışığında değerlendirildi.

Anahtar Kelimeler

• Nekrobiyozis Lipoidika
• Diyabetes Mellitus
• Pediatrik
• Deri

A Case of Pediatric Necrobiosis Lipoidica with Type 1 Diabetes Mellitus

Öz

Necrobiosis lipoidica is a granulomatous skin disease of unknown etiology and pathogenesis. The comorbidity of diabetes mellitus and necrobiosis lipoidica is frequently discussed in the literature and it is thought that microangiopathy has an important role in this comorbidity. Although necrobiosis lipoidica may occur at the same time as diabetes mellitus, it may occur before or after the diagnosis of diabetes mellitus. There is no proven effective treatment for necrobiosis lipoidica. Surgical treatment is not recommended due to koebnerization. Here, we present a 15-year-old female patient who had multiple lesions in both lower extremities for about 2 years and was diagnosed histopathologically with necrobiosis lipoidica by punch biopsy. In this case report, the etiology, clinic and treatment of necrobiosis lipoidica were evaluated in the light of the literature.

Anahtar Kelimeler

• Necrobiosis lipoidica;
• Diyabetes mellitus
• Pediatric
• Skin

Kaynakça

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