The Relationship Between Daily Carbonhydrate and Fat Intake A long with Migraine

Öz

The pathophysiology of migraine is not fully understood. The trigeminovascular pathway activation, cortical spreading depression, vascular dysfunction, pro-inflammatory and oxidative states, and gut microbiota are investigated. In this study, we aimed to evaluate the relationship between diet and migraine disease characteristics of our patients. This study was conducted with episodic migraine without aura (n:30) and chronic migraine patients (n:30). Demographic data, body mass indexes (BMI), migraine characteristics were recorded from headache diaries. Food consumption were noted Daily from diet diaries. Total calorie intake and carbohydrate and fat amounts were calculated with an internet-based calorie calculator program.The mean age was 40.1±7.83 years in chronic migraine group ( group 1), and 39.1±6.09 years in group 2. The mean BMI of group 1 was significantly higher (respectively; 28.3±3.14, and 24.9±3.29). The mean duration of migraine was found longer in group 1. The mean headache attack duration was 29.9±21.85 hours in group 1, and 29.6±22.4 was in episodic migraine without aura group (group 2). There was no significant difference between both groups in terms of headache attack duration. Average Daily carbohydrate intake is 178.53±44.86 grams in group 1, and 171.42±50.67 grams in group 2. The mean Daily fat intake was 58.01±13.65 grams in group 1 and 56.62±7.51 grams in group 2. No significant difference was found between the groups in terms of Daily calorie, mean Daily fat and, average carbohydrate intake. In our study, we did not find difference in food intake between groups, but BMI of the chronic migraine group were higher. The role of diet on the migraine pathophysiology is still under investigation. An integrative approach to migraine patients by reviewing their diet will help to understand the pathophysiology of migraine, increase the quality of life of patients and prevent unnecessary drug usage.

Anahtar Kelimeler

• Episodic migraine
• chronic migraine
• body mass index
• calorie intake
• carbohydrate intake
• fat intake

Günlük Karbonhidrat ve Yağ Alımı ile Migren Arasındaki İlişki Diyet & Migren

Öz

Migren patofizyolojisi hala tam anlaşılamamıştır. Trigeminovasküler yolak aktivasyonu, kortikal yayılan depresyon, vasküler disfonksiyon yanında proinflamatuar ve oksidatif durum,ve barsak mikrobiatası incelenmektedir. Bu çalışmada diyet özellikleriyle, migrenin hastalık karakteristikleri arasında bir ilişki olup olmadığını araştırmayı amaçladık. Bu çalışma kronik migren (grup 1) (n:30) ve epizodik aurasız migren ( grup 2) (n:30) hastalarıyla yürütüldü. Demografik bilgiler, vücut kitle indeksi (VKİ), migren hastalık özellikleri baş ağrısı günlüklerinden kaydedildi. Hastalar bir ay boyunca tükettikleri gıdaların günlüğünü tuttular. Alınan günlük ortalama kalori, karbonhidrat ve yağ miktarları internet temelli bir kalori hesaplama programıyla hesaplandı. Yaş ortalaması grup 1’de 40.1±7.83 ve grup 2’ de 39.1±6.09 yıldı. Ortalama VKİ grup 1’de daha yüksekti (sırasıyla; 28.3±3.14, and 24.9±3.29). Ortalama migren hastalık süresi grup 1’ de daha uzundu. Ortalama başağrısı atağının süresi grup 1’de 29.9±21.85, grup 2’ de 29.6±22.4 saatti. Başağrısı atağının süresi açısından gruplar arasında anlamlı fark yoktu. Günlük ortalama karbonhidrat alımı grup 1’de 178.53±44.86, grup 2’ de 171.42±50.67 gramdı. Günlük ortalama yağ alımı grup 1’de 58.01±13.65, grup 2’ de 56.62±7.51 gramdı. Günlük kalori, yağ ve karbonhidrat alımı açısından gruplar arasında anlamlı fark yoktu. Çalışmamızda gıda alımları açısından gruplar arasında fark bulmadık fakat VKİ kronik migren grubunda daha yüksekti. Diyetin migren patofizyolojisindeki rolü hala araştırılmaktadır. Migren hastalarındaki diyetlerinin de gözden geçirilerek bütüncül bir yaklaşım, migren patofizyolojisinin anlaşılmasına, hastaların yaşam kalitesinin arttırılmasına ve gereksiz ilaç kullanılmasının önlenmesine yardımcı olacaktır.

Anahtar Kelimeler

• Epizodik migren
• kronik migren
• vücut kitle indeksi
• kalori alımı
• karbonhidrat alımı
• yağ alımı

Kaynakça

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