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The Relationship Between Daily Carbonhydrate and Fat Intake A long with Migraine

Yıl 2022, , 376 - 381, 14.03.2022
https://doi.org/10.20515/otd.996232

Öz

The pathophysiology of migraine is not fully understood. The trigeminovascular pathway activation, cortical spreading depression, vascular dysfunction, pro-inflammatory and oxidative states, and gut microbiota are investigated. In this study, we aimed to evaluate the relationship between diet and migraine disease characteristics of our patients. This study was conducted with episodic migraine without aura (n:30) and chronic migraine patients (n:30). Demographic data, body mass indexes (BMI), migraine characteristics were recorded from headache diaries. Food consumption were noted Daily from diet diaries. Total calorie intake and carbohydrate and fat amounts were calculated with an internet-based calorie calculator program.The mean age was 40.1±7.83 years in chronic migraine group ( group 1), and 39.1±6.09 years in group 2. The mean BMI of group 1 was significantly higher (respectively; 28.3±3.14, and 24.9±3.29). The mean duration of migraine was found longer in group 1. The mean headache attack duration was 29.9±21.85 hours in group 1, and 29.6±22.4 was in episodic migraine without aura group (group 2). There was no significant difference between both groups in terms of headache attack duration. Average Daily carbohydrate intake is 178.53±44.86 grams in group 1, and 171.42±50.67 grams in group 2. The mean Daily fat intake was 58.01±13.65 grams in group 1 and 56.62±7.51 grams in group 2. No significant difference was found between the groups in terms of Daily calorie, mean Daily fat and, average carbohydrate intake. In our study, we did not find difference in food intake between groups, but BMI of the chronic migraine group were higher. The role of diet on the migraine pathophysiology is still under investigation. An integrative approach to migraine patients by reviewing their diet will help to understand the pathophysiology of migraine, increase the quality of life of patients and prevent unnecessary drug usage.

Kaynakça

  • Cámara-Lemarroy CR, Rodriguez-Gutierrez R, Monreal-Robles R, Marfil-Rivera A. Gastrointestinal disorders associated with migraine: A comprehensive review. World J Gastroenterol. 2016;22(36):8149-8160.
  • Razeghi Jahromi S, Ghorbani Z, Martelletti P, Lampl C, Togha M. School of Advanced Studies of the European Headache Federation (EHF-SAS). Association of diet and headache. J Headache Pain. 2019;20(1):106.
  • Di Lorenzo C, Coppola G, Sirianni G, Pierelli F. Short term improvement of migraine headaches during ketogenic diet: a prospective observational study in a dietician clinical setting. J Headache Pain. 2013;14(1):P219.
  • Evcili G, Utku U, Öğün MN, Özdemir G. Early and long period follow-up results of low glycemic index diet for migraine prophylaxis. Agrı. 2018;30(1):8–11.
  • Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211.
  • Deurenberg P, Weststrate JA, Seidell JC. Body mass index as a measure of body fatness: age- and sex-specific prediction formulas. Br J Nutr. 1991;65(2):105-114.
  • Scher A, Stewart W, Ricci J, Lipton R. Factors associated with the onset and remission of chronic daily headache in a population-based study. Pain. 2003;106(1–2):81–89.
  • Bigal ME, Liberman JN, Lipton RB. Obesity and migraine: a population study. Neurology. 2006;66(4):545–550.
  • Bigal ME, Tsang A, Loder E, Serrano D, Reed ML, Lipton RB. Body mass index and episodic headaches: a population-based study. Arch Intern Med. 2007;167(18):1964–1970.
  • Peterlin BL, Rosso AL, Rapoport AM, Scher AI. Obesity and migraine: the effect of age, gender and adipose tissue distribution. Headache. 2010;50(1):52–62.
  • Kristoffersen ES, Børte S, Hagen K, Zwart JA, Winsvold BS. Migraine, obesity and body fat distribution - a population-based study. J Headache Pain. 2020;21(1):97.
  • Goyal R, Faizy AF, Siddiqui SS, Singhai M. Evaluation of TNF-α and IL-6 levels in obese and non-obese diabetics: pre- and Postinsulin effects. N Am J Med Sci. 2012;4(4):180–184.
  • Popko K, Gorska E, Stelmaszczyk-Emmel A, Plywaczewski R, Stoklosa A, Gorecka D, et al. Proinflammatory cytokines Il-6 and TNF-α and the development of inflammation in obese subjects. Euro J Med Res. 2010;15(Suppl 2):120–122.
  • Sarchielli P, Alberti A, Baldi A, Coppola F, Rossi C, Pierguidi L, et al. Proinflammatory cytokines, adhesion molecules, and lymphocyte integrin expression in the internal jugular blood of migraine patients without aura assessed ictally. Headache. 2006;46(2):200–207.
  • Fidan I, Yuksel S, Ymir T, Irkec C, Aksakal FN. The importance of cytokines, chemokines and nitric oxide in pathophysiology of migraine. J Neuroimmunol. 2006;171(1–2):184–188.
  • Bond DS, Roth J, Nash JM, Wing RR. Migraine and obesity: epidemiology, possible mechanisms and the potential role of weight loss treatment. Obes Rev. 2011;12(5):e362–ee71.
  • Zelissen PM, Koppeschaar HP, Lips CJ, Hackeng WH. Calcitonin gene-related peptide in human obesity. Peptides. 1991;12(4):861–863. doi: 10.1016/0196-9781(91)90147-H.
  • Peterlin BL, Sacco S, Bernecker C, Scher AI. Adipokines and migraine: a systematic review. Headache. 2016;56(4):622–644.
  • Achari AE, Jain SK. Adiponectin, a therapeutic target for obesity, diabetes, and endothelial dysfunction. Int J Mol Sci. 2017;18(6):1321.
  • Ferrara L, Pacioni D, Di Fronzo V, Russo B, Speranza E, Carlino V et al. Low-lipid diet reduces frequency and severity of acute migraine attacks. Nutr Metab Cardiovasc Dis. 2015; 25(4):370–375
  • Bunner AE, Agarwal U, Gonzales JF, Valente F, Barnard ND. Nutrition intervention for migraine: a randomized crossover trial. J Headache Pain. 2014;15(1):69.
  • Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, Eshraghian MR et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69(6):371–378.
  • Di Lorenzo C, Coppola G, Sirianni G, Pierelli F. Short term improvement of migraine headaches during ketogenic diet: a prospective observational study in a dietician clinical setting. J Headache Pain.2013;14(1):P219.
  • Evans EW, Lipton RB, Peterlin BL, Raynor HA, Thomas JG, O'Leary KC, et al. Dietary intake patterns and diet quality in a nationally representative sample of women with and without severe headache or migraine. Headache. 2015;55(4):550-561.
  • Zhang M, Yang XJ. Effects of a high fat diet on intestinal microbiota and gastrointestinal diseases. World J Gastroenterol. 2016;22(40):8905-8909.
  • Agus, A, Planchais, J, Sokol, H. Gut microbiota regulation of tryptophan metabolism in health and disease. Cell Host Microbe. 2018;23(6):716-724
  • Gazerani P. Migraine and Diet. Nutrients. 2020;12(6):1658.

Günlük Karbonhidrat ve Yağ Alımı ile Migren Arasındaki İlişki Diyet & Migren

Yıl 2022, , 376 - 381, 14.03.2022
https://doi.org/10.20515/otd.996232

Öz

Migren patofizyolojisi hala tam anlaşılamamıştır. Trigeminovasküler yolak aktivasyonu, kortikal yayılan depresyon, vasküler disfonksiyon yanında proinflamatuar ve oksidatif durum,ve barsak mikrobiatası incelenmektedir. Bu çalışmada diyet özellikleriyle, migrenin hastalık karakteristikleri arasında bir ilişki olup olmadığını araştırmayı amaçladık. Bu çalışma kronik migren (grup 1) (n:30) ve epizodik aurasız migren ( grup 2) (n:30) hastalarıyla yürütüldü. Demografik bilgiler, vücut kitle indeksi (VKİ), migren hastalık özellikleri baş ağrısı günlüklerinden kaydedildi. Hastalar bir ay boyunca tükettikleri gıdaların günlüğünü tuttular. Alınan günlük ortalama kalori, karbonhidrat ve yağ miktarları internet temelli bir kalori hesaplama programıyla hesaplandı. Yaş ortalaması grup 1’de 40.1±7.83 ve grup 2’ de 39.1±6.09 yıldı. Ortalama VKİ grup 1’de daha yüksekti (sırasıyla; 28.3±3.14, and 24.9±3.29). Ortalama migren hastalık süresi grup 1’ de daha uzundu. Ortalama başağrısı atağının süresi grup 1’de 29.9±21.85, grup 2’ de 29.6±22.4 saatti. Başağrısı atağının süresi açısından gruplar arasında anlamlı fark yoktu. Günlük ortalama karbonhidrat alımı grup 1’de 178.53±44.86, grup 2’ de 171.42±50.67 gramdı. Günlük ortalama yağ alımı grup 1’de 58.01±13.65, grup 2’ de 56.62±7.51 gramdı. Günlük kalori, yağ ve karbonhidrat alımı açısından gruplar arasında anlamlı fark yoktu. Çalışmamızda gıda alımları açısından gruplar arasında fark bulmadık fakat VKİ kronik migren grubunda daha yüksekti. Diyetin migren patofizyolojisindeki rolü hala araştırılmaktadır. Migren hastalarındaki diyetlerinin de gözden geçirilerek bütüncül bir yaklaşım, migren patofizyolojisinin anlaşılmasına, hastaların yaşam kalitesinin arttırılmasına ve gereksiz ilaç kullanılmasının önlenmesine yardımcı olacaktır.

Kaynakça

  • Cámara-Lemarroy CR, Rodriguez-Gutierrez R, Monreal-Robles R, Marfil-Rivera A. Gastrointestinal disorders associated with migraine: A comprehensive review. World J Gastroenterol. 2016;22(36):8149-8160.
  • Razeghi Jahromi S, Ghorbani Z, Martelletti P, Lampl C, Togha M. School of Advanced Studies of the European Headache Federation (EHF-SAS). Association of diet and headache. J Headache Pain. 2019;20(1):106.
  • Di Lorenzo C, Coppola G, Sirianni G, Pierelli F. Short term improvement of migraine headaches during ketogenic diet: a prospective observational study in a dietician clinical setting. J Headache Pain. 2013;14(1):P219.
  • Evcili G, Utku U, Öğün MN, Özdemir G. Early and long period follow-up results of low glycemic index diet for migraine prophylaxis. Agrı. 2018;30(1):8–11.
  • Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211.
  • Deurenberg P, Weststrate JA, Seidell JC. Body mass index as a measure of body fatness: age- and sex-specific prediction formulas. Br J Nutr. 1991;65(2):105-114.
  • Scher A, Stewart W, Ricci J, Lipton R. Factors associated with the onset and remission of chronic daily headache in a population-based study. Pain. 2003;106(1–2):81–89.
  • Bigal ME, Liberman JN, Lipton RB. Obesity and migraine: a population study. Neurology. 2006;66(4):545–550.
  • Bigal ME, Tsang A, Loder E, Serrano D, Reed ML, Lipton RB. Body mass index and episodic headaches: a population-based study. Arch Intern Med. 2007;167(18):1964–1970.
  • Peterlin BL, Rosso AL, Rapoport AM, Scher AI. Obesity and migraine: the effect of age, gender and adipose tissue distribution. Headache. 2010;50(1):52–62.
  • Kristoffersen ES, Børte S, Hagen K, Zwart JA, Winsvold BS. Migraine, obesity and body fat distribution - a population-based study. J Headache Pain. 2020;21(1):97.
  • Goyal R, Faizy AF, Siddiqui SS, Singhai M. Evaluation of TNF-α and IL-6 levels in obese and non-obese diabetics: pre- and Postinsulin effects. N Am J Med Sci. 2012;4(4):180–184.
  • Popko K, Gorska E, Stelmaszczyk-Emmel A, Plywaczewski R, Stoklosa A, Gorecka D, et al. Proinflammatory cytokines Il-6 and TNF-α and the development of inflammation in obese subjects. Euro J Med Res. 2010;15(Suppl 2):120–122.
  • Sarchielli P, Alberti A, Baldi A, Coppola F, Rossi C, Pierguidi L, et al. Proinflammatory cytokines, adhesion molecules, and lymphocyte integrin expression in the internal jugular blood of migraine patients without aura assessed ictally. Headache. 2006;46(2):200–207.
  • Fidan I, Yuksel S, Ymir T, Irkec C, Aksakal FN. The importance of cytokines, chemokines and nitric oxide in pathophysiology of migraine. J Neuroimmunol. 2006;171(1–2):184–188.
  • Bond DS, Roth J, Nash JM, Wing RR. Migraine and obesity: epidemiology, possible mechanisms and the potential role of weight loss treatment. Obes Rev. 2011;12(5):e362–ee71.
  • Zelissen PM, Koppeschaar HP, Lips CJ, Hackeng WH. Calcitonin gene-related peptide in human obesity. Peptides. 1991;12(4):861–863. doi: 10.1016/0196-9781(91)90147-H.
  • Peterlin BL, Sacco S, Bernecker C, Scher AI. Adipokines and migraine: a systematic review. Headache. 2016;56(4):622–644.
  • Achari AE, Jain SK. Adiponectin, a therapeutic target for obesity, diabetes, and endothelial dysfunction. Int J Mol Sci. 2017;18(6):1321.
  • Ferrara L, Pacioni D, Di Fronzo V, Russo B, Speranza E, Carlino V et al. Low-lipid diet reduces frequency and severity of acute migraine attacks. Nutr Metab Cardiovasc Dis. 2015; 25(4):370–375
  • Bunner AE, Agarwal U, Gonzales JF, Valente F, Barnard ND. Nutrition intervention for migraine: a randomized crossover trial. J Headache Pain. 2014;15(1):69.
  • Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, Eshraghian MR et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69(6):371–378.
  • Di Lorenzo C, Coppola G, Sirianni G, Pierelli F. Short term improvement of migraine headaches during ketogenic diet: a prospective observational study in a dietician clinical setting. J Headache Pain.2013;14(1):P219.
  • Evans EW, Lipton RB, Peterlin BL, Raynor HA, Thomas JG, O'Leary KC, et al. Dietary intake patterns and diet quality in a nationally representative sample of women with and without severe headache or migraine. Headache. 2015;55(4):550-561.
  • Zhang M, Yang XJ. Effects of a high fat diet on intestinal microbiota and gastrointestinal diseases. World J Gastroenterol. 2016;22(40):8905-8909.
  • Agus, A, Planchais, J, Sokol, H. Gut microbiota regulation of tryptophan metabolism in health and disease. Cell Host Microbe. 2018;23(6):716-724
  • Gazerani P. Migraine and Diet. Nutrients. 2020;12(6):1658.
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm ORİJİNAL MAKALELER / ORIGINAL ARTICLES
Yazarlar

Ceyla Ataç Uçar 0000-0002-3810-2526

Neslihan Eşkut 0000-0003-1882-8992

Hasan Armağan Uysal 0000-0002-4867-304X

Yayımlanma Tarihi 14 Mart 2022
Yayımlandığı Sayı Yıl 2022

Kaynak Göster

Vancouver Ataç Uçar C, Eşkut N, Uysal HA. The Relationship Between Daily Carbonhydrate and Fat Intake A long with Migraine. Osmangazi Tıp Dergisi. 2022;44(3):376-81.


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