Post Covid-19 Hiponatremi Olgusu ve Literatürün Gözden Geçirilmesi

Yıl 2022, Cilt: 44 Sayı: 2, 284 - 289, 28.02.2022

Selin Meşeli Pinar Yıldız

https://doi.org/10.20515/otd.968842

Öz

2019 yılı aralık ayında başlayan Covid 19 enfeksiyonu, dünya genelindeki yaygınlığı, akut ve kronik dönem etkileri, artmış morbidite ve mortalitesi nedeniyle günümüzde de önemini korumaktadır. Seyri sırasında klinikte en sık gözlenen elektrolit bozukluğu olarak hiponatremi dikkat çekmektedir. Literatürde hiponatreminin Covid 19 enfeksiyonunda kötü prognostik sonuçlarla ilişkisi tartışılmaktadır. Biz de kliniğimizde Covid 19 enfeksiyonu sonrası erken dönemde şikayetleri devam eden, yapılan tetkiklerinde hiponatremi saptanan, adrenal yetmezlik ve hipofizer makroadenom tanısına ulaşılan bir olguyu sunmak istedik. Bu olguyla birlikte Covid 19 ve hiponatremi ilişkisi de tartışılmaya çalışılacaktır.

Anahtar Kelimeler

Covid 19 enfeksiyonu, Hiponatremi, Uygunsuz ADH sendromu

A Case of Post Covid-19 Hyponatremia and Review of the Literature

Öz

Covid 19 infection, which started in December 2019, maintains its importance today due to its worldwide prevalence, acute and chronic effects, increased morbidity and mortality. During its course, hyponatremia is the most common electrolyte disorder observed in the clinic. The relationship between hyponatremia and poor prognostic outcomes in Covid 19 infection is discussed in the literature. We present a case in the clinic, in the case of Covid 19, whose clinical examinations are still ongoing and hyponatremia macroadenoma was diagnosed in the examinations. With this case, the relationship between Covid 19 and hyponatremia will also be discussed.

Anahtar Kelimeler

Covid 19 infection, Hyponatremia, Inappropriate Antidiüretik syndrome

Kaynakça

• Kaynaklar: 1) https://covid19.saglik.gov.tr/Eklenti/39551/0/covid19rehberigenelbilgilerepidemiyolojivetanipdf.pdf
• 2) World Health Organization. Coronavirus disease (COVID-19) pandemic. Online Erişim: https://www.who.int/ emergencies/diseases/novel-coronavirus-2019.
• 3) COVID-19 rapid guideline: managing the long-term effects of COVID-19. NICE guideline, 2020. https://www.nice.org.uk/guidance/ng188.
• 4) https://blogs.bmj.com/bmj/2020/12/09/confronting-the-pathophysiology-of-long-covid/
• 5) https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects.html
• 6) Gheorghe G., Ilie M., Bungau S., Stoian AMP., Bacalbasa N., Diaconu CC. Is There a Relationship between COVID-19 and Hyponatremia? Medicina (Kaunas). 2021; 57(1): 55.
• 7) A. Berni, D. Malandrino, G. Parenti, M. Maggi, L. Poggesi, A. Per. Hyponatremia, IL-6, and SARS-CoV-2 (COVID-19) infection: may all fit together? Journal of Endocrinological Investigation. 2020; volume 43, 1137–1139.
• 8) https://turkjnephrol.org/Content/files/sayilar/335/115-131.pdf. 9) Butt I., Sawlani V., Geberhiwot T. Prolonged confusional state as first manifestation of COVID-19. Ann Clin Transl Neurol. 2020;7(8):1450-1452.
• 10) Yousaf Z., Al-Shokri SD., Al-soub H., F. H. Mohamed M. COVID-19-associated SIADH: a clue in the times of pandemic. Am J Physiol Endocrinol Metab. 2020;1: 318(6): E882–885.
• 11) Ho K.S., Narasimhan B., Kumar A., Flynn E., Salonia J., El-Hachem K., Mathew J.P. Syndrome of inappropriate antidiuretic hormone as the initial presentation of COVID-19: A novel case report. Nefrologia. 2020
• 12) De Carvalho H., Letellier T. , Karakachoff M., Desvaux G., Caillon H., Papuchon E., et al. Hyponatremia is associated with poor outcome in Covid 19. J Nephrol 2021; 7:1-8.
• 13) De La Flor Merino JC, Mola Reyes L, Linares Gravalos T, Roel Conde A, Rodeles Del Pozo M. An usual case of severe acute hyponatremia in patient with Covid 19 infection. Nefrologia (Engl Ed). 2020;40(3):356-358.