İmmunsupresyon Tedavisi Alan Karaciğer Nakli Hastalarında Yaşam Kalitesi İle Algılanan Stres Arasındaki İlişkinin Değerlendirilmesi

Öz

Amaç: Bu çalışma immunsupresyon tedavisi alan karaciğer nakli hastalarında yaşam kalitesi ile algılanan stres arasındaki ilişkinin değerlendirilmesi amacıyla yapılmıştır. Materyal ve Metot: Bu çalışma, bir üniversite hastanesinin karaciğer nakli merkezinde yatan 124 karaciğer nakli hastasının katılımıyla gerçekleştirilmiş kesitsel bir çalışmadır. Bulgular: Katılımcıların algılanan stres ölçeği (ASÖ) ile SF-36 Yaşam Kalitesi Ölçeği (SF-36) alt ölçekleri arasındaki korelasyon analizi sonucu; fiziksel fonksiyon, fiziksel rol güçlüğü, emosyonel rol güçlüğü, enerji/canlılık/vitalite, sosyal işlevsellik, genel sağlık algısı, ağrı alt boyutları arasında negatif yönde, zayıf düzeyde anlamlı bir ilişki bulunmuştur (r=-0,209 ile -0,480). ASÖ ile ruhsal sağlık alt boyutu arasında ise negatif yönde, orta düzeyde ve anlamlı bir ilişki saptanmıştır (r=-0,563). Yapılan regresyon analizi sonucunda ASÖ toplam puan ortalamasının SF-36 alt boyutlarına etkisi bakılmış ve %31,7 oranı ile en fazla ve negatif yönlü olarak ruhsal sağlık alt boyutu üzerine etkisinin olduğu bulunmuştur (R2=0,317; B= -0,962; p<0,001). Sonuç: Çalışma sonucu, karaciğer transplantasyonu sonrası erken dönemde hastaların yaşam kalitesinin ciddi düzeyde düşük olduğunu ve stresin yaşam kalitesini olumsuz yönde etkilediğini ortaya koymuştur.

Anahtar Kelimeler

• İmmünsüpresif tedavi
• karaciğer nakli
• yaşam kalitesi
• stres

Determining the Relationship Between Quality of Life and Perceived Stress in Liver Transplant Patients Receiving Immunosuppression Therapy

Abstract

Objective: This study was conducted to evaluate the relationship between quality of life and perceived stress in liver transplant patients receiving immunosuppression therapy. Materials and Methods: This study is a cross-sectional study with the participation of 124 liver transplant patients hospitalized in the liver transplantation center of a university hospital. Results: The results of the correlation analysis between the perceived stress scale (PSS) and the 36-item Short Form Health Survey (SF-36) subscales of the participants: A negative and weak significant relationship was found between physical function, physical role difficulty, emotional role difficulty, energy/vitality, social functioning, general health perception, and pain sub-dimensions (r=-0.209 and -0.480). A negative, moderate and significant relationship was found between PSS and the mental health sub-dimension (r=-0.563). As a result of the regression analysis, the effect of the PSS total score average on SF-36 sub-dimensions was examined, and it was found that it had the highest and negative effect on the mental health sub-dimension with a rate of 31.7% (R2=.317; B=-1.962; p<0.001). Conclusions: Our study results revealed that patients' quality of life was low level in the early period after liver transplantation and that stress negatively affected their quality of life.

Keywords

• Immunosuppressive therapy
• liver transplantation
• quality of life
• stress

Kaynakça

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